Effects of Second Intracellular Loop Mutations on Signal Transduction and Internalization of the Gonadotropin-releasing Hormone Receptor

Intracellular Loop ◽

Releasing Hormone ◽

The Third Intracellular Loop of the Rat Gonadotropin-Releasing Hormone Receptor Couples the Receptor to Gs- and Gq/11-Mediated Signal Transduction Pathways: Evidence from Loop Fragment Transfection in GGH3 Cells*

Endocrinology ◽

10.1210/endo.139.5.6022 ◽

1998 ◽

Vol 139 (5) ◽

pp. 2472-2478 ◽

Cited By ~ 17

Author(s):

Alfredo Ulloa-Aguirre ◽

Dinesh Stanislaus ◽

Vivek Arora ◽

Jeffrey Väänänen ◽

Shaun Brothers ◽

...

Keyword(s):

Signal Transduction ◽

Hormone Receptor ◽

Signal Transduction Pathways ◽

Intracellular Loop ◽

Releasing Hormone ◽

The Third ◽

Third Intracellular Loop ◽

Effects of Asn318 and Asp87Asn318 mutations on signal transduction by the gonadotropin-releasing hormone receptor and receptor regulation.

Endocrinology ◽

10.1210/endo.137.2.8593815 ◽

1996 ◽

Vol 137 (2) ◽

pp. 655-662 ◽

Cited By ~ 8

Author(s):

W M Awara ◽

C H Guo ◽

P M Conn

Keyword(s):

Signal Transduction ◽

Hormone Receptor ◽

Receptor Regulation ◽

Releasing Hormone ◽

Mediation of Cyclic AMP Signaling by the First Intracellular Loop of the Gonadotropin-releasing Hormone Receptor

Journal of Biological Chemistry ◽

10.1074/jbc.273.40.25581 ◽

1998 ◽

Vol 273 (40) ◽

pp. 25581-25586 ◽

Cited By ~ 63

Author(s):

Krishan K. Arora ◽

Lazar Z. Krsmanovic ◽

Nadia Mores ◽

Heather O’Farrell ◽

Kevin J. Catt

Keyword(s):

Cyclic Amp ◽

Hormone Receptor ◽

Intracellular Loop ◽

Releasing Hormone ◽

Gonadotropin Releasing Hormone Receptor ◽

Cyclic Amp Signaling

Mutations at the Consensus Phosphorylation Sites in the Third Intracellular Loop of the Rat Gonadotropin-Releasing Hormone Receptor: Effects on Receptor Ligand Binding and Signal Transduction1

Biology of Reproduction ◽

10.1095/biolreprod59.6.1470 ◽

1998 ◽

Vol 59 (6) ◽

pp. 1470-1476 ◽

Cited By ~ 7

Author(s):

Xinwei Lin ◽

Jo Ann Janovick ◽

P. Michael Conn

Keyword(s):

Ligand Binding ◽

Hormone Receptor ◽

Phosphorylation Sites ◽

Intracellular Loop ◽

Receptor Ligand ◽

Releasing Hormone ◽

The Third ◽

Third Intracellular Loop ◽

Expression and Function of the Gonadotropin-releasing Hormone Receptor Are Dependent on a Conserved Apolar Amino Acid in the Third Intracellular Loop

Journal of Biological Chemistry ◽

10.1074/jbc.274.50.35756 ◽

1999 ◽

Vol 274 (50) ◽

pp. 35756-35762 ◽

Cited By ~ 12

Author(s):

Hye-Ok Chung ◽

Qing Yang ◽

Kevin J. Catt ◽

Krishan K. Arora

Keyword(s):

Amino Acid ◽

Hormone Receptor ◽

Intracellular Loop ◽

Releasing Hormone ◽

The Third ◽

Third Intracellular Loop ◽

And Function ◽

Membrane-Proximal Region of the Carboxyl Terminus of the Gonadotropin-Releasing Hormone Receptor (GnRHR) Confers Differential Signal Transduction between Mammalian and Nonmammalian GnRHRs

Molecular Endocrinology ◽

10.1210/me.2004-0220 ◽

2005 ◽

Vol 19 (3) ◽

pp. 722-731 ◽

Cited By ~ 26

Author(s):

Da Young Oh ◽

Jung Ah Song ◽

Jung Sun Moon ◽

Mi Jin Moon ◽

Jae Il Kim ◽

...

Keyword(s):

Signal Transduction ◽

Hormone Receptor ◽

Proximal Region ◽

Carboxyl Terminus ◽

Differential Signal ◽

Releasing Hormone ◽

Membrane Proximal Region ◽

Mutations of the Conserved DRS Motif in the Second Intracellular Loop of the Gonadotropin-Releasing Hormone Receptor Affect Expression, Activation, and Internalization

Molecular Endocrinology ◽

10.1210/mend.11.9.9968 ◽

1997 ◽

Vol 11 (9) ◽

pp. 1203-1212 ◽

Cited By ~ 37

Author(s):

Krishan K. Arora ◽

Zhengyi Cheng ◽

Kevin J. Catt

Keyword(s):

Hormone Receptor ◽

Intracellular Loop ◽

Releasing Hormone ◽

Affect Expression ◽

Roles of Pyk2 in signal transduction after gonadotropin‐releasing hormone receptor stimulation

Journal of Cellular Physiology ◽

10.1002/jcp.30077 ◽

2020 ◽

Author(s):

Shiho Okitsu‐Sakurayama ◽

Sayomi Higa‐Nakamine ◽

Hidetsugu Torihara ◽

Shigeki Higashiyama ◽

Hideyuki Yamamoto

Keyword(s):

Signal Transduction ◽

Hormone Receptor ◽

Receptor Stimulation ◽

Releasing Hormone ◽

Faculty Opinions recommendation of Suppression of serum luteinizing hormone in postmenopausal women by an orally administered nonpeptide antagonist of the gonadotropin-releasing hormone receptor (NBI-42902).

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1069755.522680 ◽

2007 ◽

Author(s):

Fernando Reis

Keyword(s):

Luteinizing Hormone ◽

Postmenopausal Women ◽

Hormone Receptor ◽

Releasing Hormone ◽

Serum Luteinizing Hormone ◽

Androgen Receptor Positively Regulates Gonadotropin-releasing Hormone Receptor in Pituitary Gonadotropes

Molecular and Cellular Endocrinology ◽

10.1016/j.mce.2021.111286 ◽

2021 ◽

pp. 111286

Author(s):

Genevieve E. Ryan ◽

Stephanie C. Bohaczuk ◽

Jessica Cassin ◽

Emily A. Witham ◽

Shadi Shojaei ◽

...

Keyword(s):

Androgen Receptor ◽

Hormone Receptor ◽

Releasing Hormone ◽