The Crystal Structure of Phosphoglucose Isomerase/Autocrine Motility Factor/Neuroleukin Complexed with Its Carbohydrate Phosphate Inhibitors Suggests Its Substrate/Receptor Recognition

Motility Factor ◽

Receptor Recognition ◽

Phosphate Inhibitors

The crystal structure of a multifunctional protein: Phosphoglucose isomerase/autocrine motility factor/neuroleukin

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.96.10.5412 ◽

1999 ◽

Vol 96 (10) ◽

pp. 5412-5417 ◽

Cited By ~ 78

Author(s):

Y.-J. Sun ◽

C.-C. Chou ◽

W.-S. Chen ◽

R.-T. Wu ◽

M. Meng ◽

...

Keyword(s):

Crystal Structure ◽

Multifunctional Protein ◽

Crystal Structure of Rabbit Phosphoglucose Isomerase, a Glycolytic Enzyme That Moonlights as Neuroleukin, Autocrine Motility Factor, and Differentiation Mediator†,‡

Biochemistry ◽

10.1021/bi991604m ◽

2000 ◽

Vol 39 (5) ◽

pp. 955-964 ◽

Cited By ~ 110

Author(s):

Constance J. Jeffery ◽

Brian J. Bahnson ◽

Wade Chien ◽

Dagmar Ringe ◽

Gregory A. Petsko

Keyword(s):

Crystal Structure ◽

Glycolytic Enzyme ◽

Down-regulation of Phosphoglucose Isomerase/Autocrine Motility Factor Enhances Gensenoside Rh2 Pharmacological Action on Leukemia KG1α Cells

Asian Pacific Journal of Cancer Prevention ◽

10.7314/apjcp.2014.15.3.1099 ◽

2014 ◽

Vol 15 (3) ◽

pp. 1099-1104 ◽

Cited By ~ 10

Author(s):

Zhi-Mei You ◽

Liang Zhao ◽

Jing Xia ◽

Qiang Wei ◽

Yu-Min Liu ◽

...

Keyword(s):

Pharmacological Action ◽

Down Regulation ◽

A novel binding of GTP stabilizes the structure and modulates the activities of human phosphoglucose isomerase/autocrine motility factor

Biochemistry and Biophysics Reports ◽

10.1016/j.bbrep.2015.04.003 ◽

2015 ◽

Vol 2 ◽

pp. 14-22 ◽

Cited By ~ 2

Author(s):

Hua-Yang Lin ◽

Jyung-Hurng Liu ◽

Ka-Lik Cheng ◽

Jia-Yun Lin ◽

Ni-Rung Liu ◽

...

Keyword(s):

The complex biology of autocrine motility factor/phosphoglucose isomerase (AMF/PGI) and its receptor, the gp78/AMFR E3 ubiquitin ligase

Molecular BioSystems ◽

10.1039/b820820b ◽

2009 ◽

Vol 5 (8) ◽

pp. 793 ◽

Cited By ~ 57

Author(s):

Maria Fairbank ◽

Pascal St-Pierre ◽

Ivan R. Nabi

Keyword(s):

Ubiquitin Ligase ◽

E3 Ubiquitin Ligase ◽

Autocrine motility factor/phosphoglucose isomerase regulates ER stress and cell death through control of ER calcium release

Cell Death and Differentiation ◽

10.1038/cdd.2010.181 ◽

2011 ◽

Vol 18 (6) ◽

pp. 1057-1070 ◽

Cited By ~ 28

Author(s):

M Fu ◽

L Li ◽

T Albrecht ◽

J D Johnson ◽

L D Kojic ◽

...

Keyword(s):

Cell Death ◽

Er Stress ◽

Calcium Release ◽

Motility Factor ◽

Er Calcium

Phosphoglucose Isomerase/Autocrine Motility Factor Mediates Epithelial-Mesenchymal Transition Regulated by miR-200 in Breast Cancer Cells

Cancer Research ◽

10.1158/0008-5472.can-10-0965 ◽

2011 ◽

Vol 71 (9) ◽

pp. 3400-3409 ◽

Cited By ~ 122

Author(s):

Aamir Ahmad ◽

Amro Aboukameel ◽

Dejuan Kong ◽

Zhiwei Wang ◽

Seema Sethi ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Breast Cancer Cells ◽

Epithelial Mesenchymal Transition ◽

Mesenchymal Transition ◽

Inhibition Mechanism of Cytokine Activity of Human Autocrine Motility Factor Examined by Crystal Structure Analyses and Site-directed Mutagenesis Studies

Journal of Molecular Biology ◽

10.1016/s0022-2836(02)00186-9 ◽

2002 ◽

Vol 318 (4) ◽

pp. 985-997 ◽

Cited By ~ 22

Author(s):

Nobutada Tanaka ◽

Arayo Haga ◽

Hiroshi Uemura ◽

Hiroko Akiyama ◽

Tatsuyoshi Funasaka ◽

...

Keyword(s):

Crystal Structure ◽

Site Directed Mutagenesis ◽

Inhibition Mechanism ◽

Directed Mutagenesis ◽

Phosphoglucose Isomerase/Autocrine Motility Factor Mediates Epithelial and Mesenchymal Phenotype Conversions in Breast Cancer

Cancer Research ◽

10.1158/0008-5472.can-09-0488 ◽

2009 ◽

Vol 69 (13) ◽

pp. 5349-5356 ◽

Cited By ~ 45

Author(s):

Tatsuyoshi Funasaka ◽

Victor Hogan ◽

Avraham Raz

Keyword(s):

Breast Cancer ◽

Mesenchymal Phenotype ◽

Differential Regulation of Phosphoglucose Isomerase/Autocrine Motility Factor Activities by Protein Kinase CK2 Phosphorylation

Journal of Biological Chemistry ◽

10.1074/jbc.m409457200 ◽

2005 ◽

Vol 280 (11) ◽

pp. 10419-10426 ◽

Cited By ~ 27

Author(s):

Takashi Yanagawa ◽

Tatsuyoshi Funasaka ◽

Soichi Tsutsumi ◽

Tirza Raz ◽

Nobutada Tanaka ◽

...

Keyword(s):

Protein Kinase ◽

Protein Kinase Ck2 ◽

Differential Regulation ◽

Motility Factor ◽

Kinase Ck2