Adaptor Protein Cerebral Cavernous Malformation 3 (CCM3) Mediates Phosphorylation of the Cytoskeletal Proteins Ezrin/Radixin/Moesin by Mammalian Ste20-4 to Protect Cells from Oxidative Stress

KRIT1 loss-of-function induces a sustained Nrf2-mediated adaptive homeostasis that sensitizes cells to oxidative stress: implication for Cerebral Cavernous Malformation disease

10.1016/j.freeradbiomed.2018.04.425 ◽

2018 ◽

Vol 120 ◽

pp. S129

Author(s):

Andrea Perrelli ◽

Eliana Trapani ◽

Cinzia Antognelli ◽

Simona Delle Monache ◽

Claudia Fornelli ◽

...

Keyword(s):

Oxidative Stress ◽

Cavernous Malformation ◽

Loss Of Function

Role of cytoskeletal proteins in cerebral cavernous malformation signaling pathways: a proteomic analysis

Molecular BioSystems ◽

10.1039/c3mb70199a ◽

2014 ◽

Vol 10 (7) ◽

pp. 1881-1889 ◽

Cited By ~ 10

Author(s):

Sarah Schwartz Baxter ◽

Christopher F. Dibble ◽

Warren C. Byrd ◽

Jim Carlson ◽

Charles Russell Mack ◽

...

Keyword(s):

Systems Biology ◽

Signaling Pathways ◽

Proteomic Analysis ◽

Cavernous Malformation ◽

Cytoskeletal Proteins ◽

Anin vitroproteomics and systems biology of cerebral cavernous malformation.

Altered redox signaling and oxidative stress: the emerging faces of Cerebral Cavernous Malformation (CCM) pathogenesis

10.1016/j.freeradbiomed.2016.04.143 ◽

2016 ◽

Vol 96 ◽

pp. S66

Author(s):

Saverio Francesco Retta

Keyword(s):

Oxidative Stress ◽

Cavernous Malformation ◽

Redox Signaling ◽

And Oxidative Stress

Oxidative Stress and inflammation in cerebral cavernous malformation disease pathogenesis: Toward a unifying mechanistic and therapeutic landscape

10.1016/j.freeradbiomed.2018.04.053 ◽

2018 ◽

Vol 120 ◽

pp. S12

Author(s):

Saverio Francesco Retta

Keyword(s):

Oxidative Stress ◽

Cavernous Malformation ◽

Disease Pathogenesis ◽

Therapeutic Landscape

Crystal structure of human programmed cell death 10 complexed with inositol-(1,3,4,5)-tetrakisphosphate: A novel adaptor protein involved in human cerebral cavernous malformation

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2010.07.119 ◽

2010 ◽

Vol 399 (4) ◽

pp. 587-592 ◽

Cited By ~ 11

Author(s):

Jingjin Ding ◽

Xiaoyan Wang ◽

De-Feng Li ◽

Yonglin Hu ◽

Ying Zhang ◽

...

Keyword(s):

Crystal Structure ◽

Cell Death ◽

Programmed Cell Death ◽

Cavernous Malformation ◽

Adaptor Protein ◽

Novel CCM1 (KRIT1) Mutation Detection in Brazilian Familial Cerebral Cavernous Malformation: Different Genetic Variants in Inflammation, Oxidative Stress, and Drug Metabolism Genes Affect Disease Aggressiveness

World Neurosurgery ◽

10.1016/j.wneu.2020.02.119 ◽

2020 ◽

Vol 138 ◽

pp. 535-540.e8 ◽

Cited By ~ 1

Author(s):

Fabrícia Lima Fontes-Dantas ◽

Gustavo da Fontoura Galvão ◽

Elielson Veloso da Silva ◽

Soniza Alves-Leon ◽

Cláudia Cecília da Silva Rêgo ◽

...

Keyword(s):

Oxidative Stress ◽

Drug Metabolism ◽

Genetic Variants ◽

Mutation Detection ◽

Cavernous Malformation ◽

Familial Cerebral Cavernous Malformation

Oxidative stress and inflammation in cerebral cavernous malformation disease pathogenesis: Two sides of the same coin

The International Journal of Biochemistry & Cell Biology ◽

10.1016/j.biocel.2016.09.011 ◽

2016 ◽

Vol 81 ◽

pp. 254-270 ◽

Cited By ~ 43

Author(s):

Saverio Francesco Retta ◽

Angela J. Glading

Keyword(s):

Oxidative Stress ◽

Cavernous Malformation ◽

Disease Pathogenesis ◽

Two Sides

KRIT1 loss-of-function induces a chronic Nrf2-mediated adaptive homeostasis that sensitizes cells to oxidative stress: Implication for Cerebral Cavernous Malformation disease

10.1016/j.freeradbiomed.2017.11.014 ◽

2018 ◽

Vol 115 ◽

pp. 202-218 ◽

Cited By ~ 29

Author(s):

Cinzia Antognelli ◽

Eliana Trapani ◽

Simona Delle Monache ◽

Andrea Perrelli ◽

Martina Daga ◽

...

Keyword(s):

Oxidative Stress ◽

Cavernous Malformation ◽

Loss Of Function

The Role of Oxidative Stress in Cerebral Cavernous Malformation (CCM) Pathogenesis: From Disease Mechanisms toward Therapeutic Approaches

10.1016/j.freeradbiomed.2015.10.147 ◽

2015 ◽

Vol 87 ◽

pp. S56

Author(s):

Eliana Trapani ◽

Saverio Marchi ◽

Helene Choquet ◽

Luca Goitre ◽

Andrea Moglia ◽

...

Keyword(s):

Oxidative Stress ◽

Cavernous Malformation ◽

Therapeutic Approaches ◽

Disease Mechanisms

Polymorphisms in genes related to oxidative stress and inflammation: Emerging links with the pathogenesis and severity of Cerebral Cavernous Malformation disease

10.1016/j.freeradbiomed.2021.06.021 ◽

2021 ◽

Author(s):

Andrea Perrelli ◽

Saverio Francesco Retta

Keyword(s):

Oxidative Stress ◽

Cavernous Malformation ◽