scholarly journals Insight into the Human DNA Primase Interaction with Template-Primer

2015 ◽  
Vol 291 (9) ◽  
pp. 4793-4802 ◽  
Author(s):  
Andrey G. Baranovskiy ◽  
Yinbo Zhang ◽  
Yoshiaki Suwa ◽  
Jianyou Gu ◽  
Nigar D. Babayeva ◽  
...  
Keyword(s):  
Genomics ◽  
1997 ◽  
Vol 44 (2) ◽  
pp. 251-252
Author(s):  
Akiko Shiratori ◽  
Katsuzumi Okumura ◽  
Masahiro Nogami ◽  
Hiroshi Taguchi ◽  
Tokiro Onozaki ◽  
...  

Genomics ◽  
1995 ◽  
Vol 28 (2) ◽  
pp. 350-353 ◽  
Author(s):  
Akiko Shiratori ◽  
Katsuzumi Okumura ◽  
Masahiro Nogami ◽  
Hiroshi Taguchi ◽  
Tokiro Onozaki ◽  
...  

Molecules ◽  
2020 ◽  
Vol 25 (24) ◽  
pp. 5847
Author(s):  
Satheesh Gujarathi ◽  
Maroof Khan Zafar ◽  
Xingui Liu ◽  
Robert L. Eoff ◽  
Guangrong Zheng

Garcinoic acid has been identified as an inhibitor of DNA polymerase β (pol β). However, no structure-activity relationship (SAR) studies of garcinoic acid as a pol β inhibitor have been conducted, in part due to the lack of an efficient synthetic method for this natural product and its analogs. We developed an efficient semi-synthetic method for garcinoic acid and its analogs by starting from natural product δ-tocotrienol. Our preliminary SAR studies provided a valuable insight into future discovery of garcinoic acid-based pol β inhibitors.


2019 ◽  
Vol 88 (1) ◽  
pp. 41-56 ◽  
Author(s):  
Győző L. Kaján ◽  
Andor Doszpoly ◽  
Zoltán László Tarján ◽  
Márton Z. Vidovszky ◽  
Tibor Papp

Abstract Viruses have been infecting their host cells since the dawn of life, and this extremely long-term coevolution gave rise to some surprising consequences for the entire tree of life. It is hypothesised that viruses might have contributed to the formation of the first cellular life form, or that even the eukaryotic cell nucleus originates from an infection by a coated virus. The continuous struggle between viruses and their hosts to maintain at least a constant fitness level led to the development of an unceasing arms race, where weapons are often shuttled between the participants. In this literature review we try to give a short insight into some general consequences or traits of virus–host coevolution, and after this we zoom in to the viral clades of adenoviruses, herpesviruses, nucleo-cytoplasmic large DNA viruses, polyomaviruses and, finally, circoviruses.


Science ◽  
2017 ◽  
Vol 357 (6348) ◽  
pp. eaan2762 ◽  
Author(s):  
Elizabeth O’Brien ◽  
Marilyn E. Holt ◽  
Matthew K. Thompson ◽  
Lauren E. Salay ◽  
Aaron C. Ehlinger ◽  
...  

PLoS ONE ◽  
2018 ◽  
Vol 13 (12) ◽  
pp. e0209345 ◽  
Author(s):  
Marilyn E. Holt ◽  
Lauren E. Salay ◽  
Elizabeth O’Brien ◽  
Jacqueline K. Barton ◽  
Walter J. Chazin

Biochemistry ◽  
2002 ◽  
Vol 41 (47) ◽  
pp. 14066-14075 ◽  
Author(s):  
Chad L. Moore ◽  
Molly Chiaramonte ◽  
Tamara Higgins ◽  
Robert D. Kuchta

Biochemistry ◽  
2002 ◽  
Vol 41 (15) ◽  
pp. 4891-4900 ◽  
Author(s):  
Laura K. Zerbe ◽  
Robert D. Kuchta
Keyword(s):  

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