The Development of Group Psychotherapy in a Clinical Research Setting

1959 ◽  
Vol 9 (4) ◽  
pp. 504-509
Author(s):  
Harold A. Rashkis
Keyword(s):  
Clinical Research ◽  
Group Psychotherapy ◽  
Research Setting

scholarly journals Validation of a commercial human ELISA to measure hyaluronic acid concentration in feline plasma

2021 ◽  
pp. 104063872110447
Author(s):  
Kaela E. Shaw ◽  
Alexa M. Bersenas ◽  
Shane W. Bateman ◽  
Shauna L. Blois ◽  
R. Darren Wood
Keyword(s):  
Hyaluronic Acid ◽  
Clinical Research ◽  
Critically Ill ◽  
Acid Concentration ◽  
Extraction Efficiency ◽  
Analytical Performance ◽  
Research Setting ◽  
Assay Validation ◽  
Validation Methods ◽  
Precision Study

Our goal was to validate a human hyaluronic acid (HA) ELISA (Hyaluronic acid plus ELISA; TECOmedical Group) for use in feline plasma. Plasma from 5 healthy cats and 5 critically ill cats was used for validation of the assay. Validation methods performed included intra- and inter-assay variability, spike-and-recovery, and dilutional linearity. All measurements were performed in duplicate. The precision study revealed good intra-assay CV of 7.4–8.9%; inter-assay CV was 3.4–4.2%. Extraction efficiency via spiking tests yielded mean recovery of 89.6%. The assay met criteria for acceptable linearity using 3 serial dilutions. Our results demonstrate that this commercial HA ELISA had acceptable analytical performance using feline plasma and could be a useful tool in the veterinary clinical research setting.

scholarly journals Adherence Patterns and Adherence-Related DNA Sequences in Escherichia coli Isolates from Children with and without Diarrhea in São Paulo City, Brazil

1998 ◽  
Vol 36 (12) ◽  
pp. 3609-3613 ◽  
Author(s):  
Tânia A. T. Gomes ◽  
Mônica A. M. Vieira ◽  
Cecilia M. Abe ◽  
Daleth Rodrigues ◽  
Patricia M. Griffin ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Clinical Research ◽  
Dna Sequences ◽  
Acute Diarrhea ◽  
Dna Probes ◽  
Research Setting ◽  
E Coli ◽  
Aggregative Adherence

The correlation between various adherence patterns and adherence-related DNA sequences in Escherichia coliisolates from 1- to 4-year-old children with and without diarrhea in São Paulo, Brazil, was evaluated. A total of 1,801 isolates obtained from 200 patients and 200 age-matched controls were studied. The adherence patterns found were classified as diffuse, aggregative, aggregative in a 6-h assay, aggregative predominantly in coverslips, localized, localized-like, and noncharacteristic. In general, the DNA sequences used as probes showed excellent specificities (>93%), but their sensitivities varied. Thus, the results of bioassays and assays with DNA probes normally used to search for adherent E. coli did not correlate well, and the best method for the identification of these organisms in the clinical research setting remains controversial. Isolates presenting diffuse adherence or hybridizing with the related daaC probe, or both, were by far the most frequent in patients (31.5, 26.0, and 23.0%, respectively), followed by isolates presenting aggregative adherence or hybridizing with the related EAEC probe, or both (21.5, 13.0, and 10.5%, respectively). None of the different combinations of adherence patterns and adherence-related DNA sequences found were associated with acute diarrhea.

Real-life Clinical Implementation of PAD Rehabilitation in Rural Minnesota vs. the Clinical Research Setting: Sicker, Slower, and More Symptomatic

2018 ◽  
Vol 36 (2) ◽  
pp. 103
Author(s):  
Rebecca Brown ◽  
Laurissa Stigen ◽  
Alanna Gerard ◽  
Kristin Erickson ◽  
Diane Treat-Jacobson ◽  
...  
Keyword(s):  
Clinical Research ◽  
Real Life ◽  
Clinical Implementation ◽  
Research Setting

scholarly journals Endometrial scratching can be offered outside clinical research setting: let us show you why

2021 ◽  
Vol 36 (5) ◽  
pp. 1447-1449 ◽  
Author(s):  
Amerigo Vitagliano ◽  
Attilio Di Spiezio Sardo ◽  
Marco Noventa ◽  
Jose Carugno ◽  
Ettore Cicinelli ◽  
...  
Keyword(s):  
Clinical Research ◽  
Research Setting ◽  
Endometrial Scratching

scholarly journals Orthopaedic clinical research: building a team that lasts

2021 ◽  
Vol 6 (4) ◽  
pp. 245-251
Author(s):  
Laura Stiegel ◽  
Alison K. Klika ◽  
Carlos A. Higuera ◽  
Wael K.Barsoum ◽  
Nicolas S. Piuzzi
Keyword(s):  
Clinical Research ◽  
Time Management ◽  
Orthopaedic Surgery ◽  
Research Team ◽  
Team Building ◽  
Research Programme ◽  
Research Setting ◽  
Quality Research ◽  
Medical Progress

Medical progress, including in the orthopaedic surgery field, depends on the interaction and collaboration between: physicians, with their expertise on the clinical setting; scientists, with their expertise on the research setting; and professionals who are skilled in both settings (clinical scientists). This leads to the need to develop research approaches which involves people who are committed and support the process, strategic planning, and a cohesive team that can execute the tasks. All these interactions must be supported financially in order to maintain the long-term viability of such team. Time management is crucial for the clinical research team. To ensure success, the research team must be flexible in order to adapt to dynamic clinical and surgical schedules. It is especially important that surgeons have regular, dedicated quality research time to maintain a consistent interaction with the team. Building a successful and productive orthopaedic clinical research programme involves many challenges in creating proper leadership, obtaining funding, setting proper resources, establishing necessary training, and providing guidance and insight around the importance of each role that every member plays on the team. Cite this article: EFORT Open Rev 2021;6:245-251. DOI: 10.1302/2058-5241.6.200058

Sign in / Sign up

Export Citation Format

Share Document