Experimentally Induced Motion Sickness in Fish: Possible Role of the Otolith Organs

2003 ◽  
Vol 123 (4) ◽  
pp. 488-492 ◽  
Author(s):  
Kai Helling ◽  
Stefan Hausmann ◽  
Andrew Clarke ◽  
Hans Scherer



2015 ◽  
Vol 40 (3) ◽  
pp. 163-172 ◽  
Author(s):  
Bjoern Horing ◽  
Katja Weimer ◽  
Eric R. Muth ◽  
Paul Enck


1964 ◽  
Vol 42 (6) ◽  
pp. 793-801 ◽  
Author(s):  
K. E. Money ◽  
J. Friedberg

The discrete surgical inactivation of all six semicircular canals was found to be equivalent to bilateral labyrinthectomy in eliminating motion sickness in dogs, even though the otolith organs remained functional. Inactivation of fewer than six of the canals reduced the susceptibility of dogs to motion sickness, but to a lesser degree than did inactivation of all six canals. These findings are consistent with the theory that stimulation of the semicircular canals causes motion sickness.Rotatory tests of the horizontal and vertical semicircular canals and tests of an otolith reflex, preoperatively and postoperatively, yielded information about the basic functions of the semicircular canals and confirmed that the surgical procedures had accomplished their objectives without unintended damage to other vestibular receptors.





1957 ◽  
Vol 190 (3) ◽  
pp. 578-580 ◽  
Author(s):  
S. C. Wang ◽  
H. I. Chinn ◽  
A. A. Renzi

Motion sickness was experimentally induced in dogs by means of a standardized swinging procedure. Subsequently, 21 susceptible dogs were chosen in this series for abdominal sympathectomy and/or abdominal vagotomy. Over a period of about 6 months, these operated animals were retested several times, and it was found that the majority of them (67%) showed increased resistance to swing sickness to a greater or lesser degree. However, because of the relatively high percentage of the remaining dogs which showed no alteration of their swing sensitivity, it is concluded that the visceral afferents from the gastrointestinal tract play no paramount role in experimental motion sickness.



PLoS ONE ◽  
2021 ◽  
Vol 16 (1) ◽  
pp. e0245295
Author(s):  
Suzanne A. E. Nooij ◽  
Christopher J. Bockisch ◽  
Heinrich H. Bülthoff ◽  
Dominik Straumann

Illusory self-motion often provokes motion sickness, which is commonly explained in terms of an inter-sensory conflict that is not in accordance with previous experience. Here we address the influence of cognition in motion sickness and show that such a conflict is not provocative when the observer believes that the motion illusion is indeed actually occurring. Illusory self-motion and motion sickness were elicited in healthy human participants who were seated on a stationary rotary chair inside a rotating optokinetic drum. Participants knew that both chair and drum could rotate but were unaware of the actual motion stimulus. Results showed that motion sickness was correlated with the discrepancy between participants’ perceived self-motion and participants’ beliefs about the actual motion. Together with the general motion sickness susceptibility, this discrepancy accounted for 51% of the variance in motion sickness intensity. This finding sheds a new light on the causes of visually induced motion sickness and suggests that it is not governed by an inter-sensory conflict per se, but by beliefs concerning the actual self-motion. This cognitive influence provides a promising tool for the development of new countermeasures.







Author(s):  
Behrang Keshavarz ◽  
Alison C. Novak ◽  
Lawrence J. Hettinger ◽  
Thomas A. Stoffregen ◽  
Jennifer L. Campos


Author(s):  
A. Kawaoi

Numbers of immunological approach have been made to the amyloidosis through the variety of predisposing human diseases and the experimentally induced animals by the greater number of agents. The results suggest an important role of impaired immunity involving both humoral and cell-mediated aspects.Recently the author has succeeded in producing amyloidosis in the rabbits and mice by the injections of immune complex of heat denatured DNA.The aim of this report is to demonstrate the details of the ultrastructure of the amyloidosis induced by heterologous insoluble immune complex. Eleven of twelve mice, dd strain, subcutaneously injected twice a week with Freund's complete adjuvant and four of seven animals intraperitonially injected developed systemic amyloidosis two months later from the initial injections. The spleens were electron microscopically observed.



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