Abstract
Captan, folpet, and Difolatan® are structurally related fungicides. Major metabolites derived from these compounds are the imides: tetrahydrophthalimide and phthalimide. The epoxides of captan and Difolatan are possible alteration products which may form under conditions of weathering or degradative metabolism. A TLC method has been developed which differentiates between captan, folpet, Difolatan, tetrahydrophthalimide, phthalimide, captan epoxide, Difolatan epoxide, and tetrahydrophthalimide epoxide. The method is based upon chromatography on silica gel with 1% methanol in chloroform as solvent for development, followed by sequential color development of the resulting spots. N,NDimethyl - p - phenylenediamine, potassium permanganate, and chromic acid were the chromogenic sprays used. Lower limits of detection for these compounds were determined in the named TLC system. The GLC behavior of this group of compounds was also studied, utilizing both a 10% DC-200 on Gas Chrom Q (80—100 mesh) column and a mixed column of 10% DC-200:15% QF-1 (1:1) each on 100-120 mesh Gas Chrom Q. GLC retention times and response data were determined with an electron capture detector
Oxidative cleavage of alcohols by cerium (IV) and chromic acid
