Synthesis, structures, and characterization of copper(II), nickel(II), and cobalt(III) metal complexes derived from an asymmetric bidentate Schiff-base ligand

2008 ◽  
Vol 61 (8) ◽  
pp. 1212-1220 ◽  
Author(s):  
Yanhong Song ◽  
Zhanwei Xu ◽  
Qingjin Sun ◽  
Biyun Su ◽  
Quanchang Gao ◽  
...  
2019 ◽  
Vol 1181 ◽  
pp. 536-545 ◽  
Author(s):  
Rania H. Taha ◽  
Zienab A. El-Shafiey ◽  
Aida A. Salman ◽  
Esmail M. El-Fakharany ◽  
Mai M. Mansour

2021 ◽  
Vol 11 (1) ◽  
pp. 3249-3260

Herein, we describe the synthesis and characterization of a Schiff base ligand (E)-N'-(2-hydroxybenzylidene)-4-methoxybenzohydrazide (HBMB) and its Mn(II), Ni(II), and Cu(II) metal complexes (C1-C3) respectively. The ligand HBMB was synthesized by reacting condensation of salicylaldehyde and 4-methoxy benzohydrazide in a 1:1 molar ratio. The structure of HBMB and its metal complexes (C1-C3) were evaluated by using UV-Vis, FT-IR, 1H-NMR, mass spectroscopy as well as on the basis of elemental analysis, conductivity measurements, and thermogravimetric techniques (TGA). The synthesized molecules' tumoricidal properties were performed against human breast cancer (MCF-7) and colon cancer (HT 29) cell lines. The biological results indicated that the ligand, HBMB, and metal complexes possess dose-dependent selective cytotoxicity against the tested carcinoma cells. The synthesized compounds were further evaluated for their in vitro antimicrobial activities against Gram-positive bacteria (Staphylococcus aureus), Gram-negative bacteria (Escherichia coli), and fungal strains (Aspergillus niger).


2020 ◽  
Vol 74 (11) ◽  
pp. 3825-3837
Author(s):  
Imène Bougossa ◽  
Djouhra Aggoun ◽  
Ali Ourari ◽  
Raúl Berenguer ◽  
Sofiane Bouacida ◽  
...  

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