Chiral heterocyclic ligands. XVII. Pyridine–amino acid hybrid ligands: synthesis and crystal structures of metal complexes of a chelating ligand derived from L-alanine

Abstract N,N-Dimethyl-C-phenylglycinemethylester reacts with Pd(OAc)2 in acetic acid to give the orthopalladated, acetato bridged complex 1. Treatment of 1 with sodium halide affords the chloro, bromo, and iodo bridged compounds [Me2NC(H)(CO2Me)C6H4PdX]2 (2a -c) (X = halide). From 2a and 1,1′-bis(diphenylphosphino)ferrocene the phosphine bridged trinuclear complex 3 is obtained. Substitution of the amine ligand of 2a by the phosphino group is observed for the reaction of 2a with Ph2PC(Me)C(Me)PPh2. Insertion of 2,6-dimethyl-phenylisocyanide, CO, alkyl-vinyl-ketones, and diphenylacetylene into the Pd-C bond o f 2a -c provides the orthosubstituted organic and organometallic derivatives of phenylglycine 6a -c, 7, 8a -b and 9a -c. The crystal structures of 1, 4a, 6a, 7 and 9a were determined by X-ray diffraction.

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3H-1,3-Azaphospholo[4,5-b]pyridines – novel heterocyclic P,N-bridging or hybrid ligands: synthesis and first d8-transition metal complexes

Dalton Transactions ◽

10.1039/c5dt04073f ◽

2016 ◽

Vol 45 (5) ◽

pp. 2261-2272 ◽

Cited By ~ 1

Author(s):

Mohamed Shaker S. Adam ◽

Markus K. Kindermann ◽

Peter G. Jones ◽

Joachim W. Heinicke

Keyword(s):

Transition Metal ◽

Metal Complexes ◽

Transition Metal Complexes ◽

Heterocyclic Ligands ◽

Hybrid Ligands

Novel bicyclic P,N-heterocyclic ligands and the first P- and P,N-coordinated LM(0)(CO)5, LRh(COD)Cl, (LPd(All)Cl)2PdCl2 and (LPdCl2)2 transition metal complexes thereof are presented.

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Synthesis, Characterization and Biological Activity of Nitrogen Oxygen-Sulfur (NOS) Transition Metal Complexes Derived from Novel S-2,4-dichlorobenzyldithiocarbazate with 5-fluoroisatin

Scientific Research Journal ◽

10.24191/srj.v7i2.9420 ◽

2010 ◽

Vol 7 (2) ◽

pp. 67

Author(s):

Mohd Abdul Fatah Abdul Manan ◽

Hadariah Bahron ◽

Karimah Kassim ◽

Mohd Asrul Hafaz Mohamad ◽

Syed Nazmi Sayed Mohamad

Keyword(s):

Bacillus Subtilis ◽

Schiff Base ◽

Metal Complexes ◽

Condensation Reaction ◽

Schiff Base Complex ◽

Inhibition Zone ◽

Azomethine Nitrogen ◽

Strong Activity ◽

Chelating Ligand ◽

Physico Chemical

A novel Schiff base containing nitrogen-oxygen-sulfur (NOS) donor atoms formed from the condensation reaction of S-2,4-dichlorobenzyldithiocarbazate (S-2,4BDTC) with 5-fluroisatin has been synthesized. Complexes of cobalt(II), nickel(II), copper(II), zinc(II) and cadmium(II) with this Schiff base have been prepared and characterized using elemental analysis and various physico-chemical techniques. In the cobalt(II) and nickel(II) complexes the Schiff base behaves as a uninegatively charged tridentate nitrogen-oxygen-sulfur (NOS) chelating ligand, bonding through the azomethine nitrogen, thiolate sulfur and carbonylic oxygen of the isatin moiety. However, in the copper(II), zinc(II) and cadmium(II) complexes the Schiff base behaves as a nitrogen-sulfur (NS) bidentate chelating ligand, bonding through the azomethine nitrogen and thiolate sulfur. The Schiff base and the metal complexes were evaluated with respect to antimicrobial activity, which was performed in relation to two selected pathogenic microbials (Bacillus subtilis and Pseudomonas aeruginosa). It was observed that only the zinc Schiff base complex exhibited strong activity against the Bacillus subtilis bacteria with an inhibition zone of 25 mm.

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Synthesis, Characterization and Biological Activity of NitrogenOxygen-Sulfur (NOS) Transition Metal Complexes Derived from Novel S-2,4-dichlorobenzyldithiocarbazate with 5-fluoroisatin

Scientific Research Journal ◽

10.24191/srj.v7i2.5027 ◽

2010 ◽

Vol 7 (2) ◽

pp. 67

Author(s):

Mohd Abdul Fatah Abdul Manan ◽

Hadariah Bahron ◽

Karimah Kassim ◽

Mohd Asrul Hafiz Muhamad ◽

Syed Nazmi Sayed Mohamad

Keyword(s):

Bacillus Subtilis ◽

Schiff Base ◽

Metal Complexes ◽

Transition Metal Complexes ◽

Condensation Reaction ◽

Inhibition Zone ◽

Azomethine Nitrogen ◽

Strong Activity ◽

Chelating Ligand ◽

Physico Chemical

A novel Schiff base containing nitrogen-oxygen-sulfur (NOS) donor atoms formed from the condensation reaction of S-2,4- dichlorobenzyldithiocarbazate (S-2.4BDTC) with 5-fluroisatin has been synthesized. Complexes of cobalt(ll), nickel(ll), copper(ll), zinc(ll) and cadmium(ll) with this Schiff base have been prepared and characterized using elemental analysis and various physico-chemical techniques. In the cobalt(ll) and nickel(II) complexes the SchifJbase behaves as a uninegatively charged tridentate nitrogen-oxygen-sulfur (NOS) chelating ligand, bonding through the azomethine nitrogen, thiolate sulfur and carbonylic oxygen of the isatin moiety. However. in the copper(ll), zinc(II) and cadmium(II) complexes the Schiff base behaves as a nitrogen-sulfur (NS) bidentate chelating ligand, bonding through the azomethine nitrogen and thiolate sulfur. The Schiff base and the metal complexes were evaluated with respect to antimicrobial activity, which was performed in reallion to two selected pathogenic microbials (Bacillus subtilis and Pseudomonas aeruginosa). It was observed that only the zinc Schiffbase complex exhibited strong activity against the Bacillus subtilis bacteria with an inhibition zone of25 mm.

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Terpyridine–tetrathiafulvalene hybrid ligands and their electroactive metal complexes

New Journal of Chemistry ◽

10.1039/c3nj00041a ◽

2013 ◽

Vol 37 (5) ◽

pp. 1427 ◽

Cited By ~ 15

Author(s):

Esmah Belhadj ◽

Abdelkrim El-Ghayoury ◽

Emilie Ripaud ◽

Leokadiya Zorina ◽

Magali Allain ◽

...

Keyword(s):

Metal Complexes ◽

Hybrid Ligands

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Functionalised Terpyridines and Their Metal Complexes—Solid-State Interactions

Chemistry ◽

10.3390/chemistry3010016 ◽

2021 ◽

Vol 3 (1) ◽

pp. 199-227

Author(s):

Young Hoon Lee ◽

Jee Young Kim ◽

Sotaro Kusumoto ◽

Hitomi Ohmagari ◽

Miki Hasegawa ◽

...

Keyword(s):

Solid State ◽

Metal Complexes ◽

Crystal Structures ◽

Weak Interactions ◽

Dispersion Interactions ◽

Derivatives Of

Analysis of the weak interactions within the crystal structures of 33 complexes of various 4′-aromatic derivatives of 2,2′:6′,2″-terpyridine (tpy) shows that interactions that exceed dispersion are dominated, as expected, by cation⋯anion contacts but are associated with both ligand–ligand and ligand–solvent contacts, sometimes multicentred, in generally complicated arrays, probably largely determined by dispersion interactions between stacked aromatic units. With V(V) as the coordinating cation, there is evidence that the polarisation of the ligand results in an interaction exceeding dispersion at a carbon bound to nitrogen with oxygen or fluorine, an interaction unseen in the structures of M(II) (M = Fe, Co, Ni, Cu, Zn, Ru and Cd) complexes, except when 1,2,3-trimethoxyphenyl substituents are present in the 4′-tpy.

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