Comprehensive biological evaluation (DNA-binding, cleavage, and antimicrobial activity) of β-diketimine Schiff base ligands and their Cu(II) and Zn(II) complexes

Three Cu(ii) complexes (C1–C3) were designed and synthesized.C3, in particular, having a ligand derived from benzocaine, exhibited greater selectivity toward HeLa cells, arrested cell cycles, and promoted tumor cell apoptosis.

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DNA binding, BSA interaction and SOD activity of two new nickel(II) complexes with glutamine Schiff base ligands

Journal of Photochemistry and Photobiology B Biology ◽

10.1016/j.jphotobiol.2016.03.053 ◽

2016 ◽

Vol 161 ◽

pp. 355-367 ◽

Cited By ~ 39

Author(s):

Qiang Wei ◽

Jianfang Dong ◽

Peiran Zhao ◽

Manman Li ◽

Fengling Cheng ◽

...

Keyword(s):

Schiff Base ◽

Dna Binding ◽

Schiff Base Ligands ◽

Sod Activity ◽

Bsa Interaction

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Synthesis, characterization, DNA binding, photo-induced DNA cleavage, and antimicrobial activity of metal complexes of a Schiff base derived from bis(3-aminophenyl)malonamide

Journal of Coordination Chemistry ◽

10.1080/00958970903288294 ◽

2009 ◽

Vol 62 (24) ◽

pp. 3969-3985 ◽

Cited By ~ 15

Author(s):

N. Raman ◽

A. Sakthivel ◽

R. Jeyamurugan

Keyword(s):

Antimicrobial Activity ◽

Schiff Base ◽

Dna Binding ◽

Metal Complexes ◽

Dna Cleavage

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Polydentate Schiff Base Ligands and Their La(III) Complexes: Synthesis, Characterization, Antibacterial, Thermal, and Electrochemical Properties

International Journal of Inorganic Chemistry ◽

10.1155/2012/791219 ◽

2012 ◽

Vol 2012 ◽

pp. 1-11 ◽

Cited By ~ 6

Author(s):

Ali E. Şabik ◽

Muharrem Karabörk ◽

Gökhan Ceyhan ◽

Mehmet Tümer ◽

Metin Dığrak

Keyword(s):

Antimicrobial Activity ◽

Schiff Base ◽

Electrochemical Properties ◽

Antimicrobial Activities ◽

Nitrogen Atmosphere ◽

Spectroscopic Methods ◽

Schiff Base Ligands ◽

One Step ◽

The One ◽

Reversible Transfer

We synthesized the Schiff base ligands H2L1–H2L4 and their La(III) complexes and characterized them by the analytical and spectroscopic methods. We investigated their electrochemical and antimicrobial activity properties. The electrochemical properties of the ligands H2L1–H2L4 and their La(III) complexes were studied at the different scan rates (100 and 200 mV), different pH ranges (), and in the different solvents. The electrooxidation of the Schiff base ligands involves a reversible transfer of two electrons and two protons in solutions of pH up to 5.5, in agreement with the one-step two-electron mechanism. In solutions of pH higher than 5.5, the process of electrooxidation reaction of the Schiff base ligands and their La(III) complexes follows an ECi mechanism. The antimicrobial activities of the ligands and their complexes were studied. The thermal properties of the metal complexes were studied under nitrogen atmosphere in the range of temperature 20–1000°C.

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