A Review of “Multidetector Computed Tomography in Cerebrovascular Disease; CT Perfusion Imaging”

2009 ◽  
Vol 33 (4) ◽  
pp. 214-215
Author(s):  
Lotfi Hacein-Bey
2007 ◽  
Vol 48 (5) ◽  
pp. 539-539
Author(s):  
Till Schellhorn

Multidetector Computed Tomography in Cerebrovascular Disease: CT Perfusion Imaging. Edited by K. Miles, J. D. Eastwood & M. König. Abingdon, UK: Informa Healthcare Ltd., 2007. ISBN: 9781842143155; ISBN-10: 1842143158. 192 pages. Price hardcover: $129.95


2015 ◽  
Vol 5 (8) ◽  
pp. 1931-1935
Author(s):  
Z. Q. Sun ◽  
X. H. Li ◽  
Z. Wang ◽  
W. Cai ◽  
L. Chen ◽  
...  

Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
Richard T George ◽  
Omair Yousuf ◽  
Kakuya Kitagawa ◽  
Hyuk-Jae Chang ◽  
David A Bluemke ◽  
...  

Introduction: The advent of 256x0.5 mm high resolution multidetector computed tomography (MDCT) created the potential to quantify subendocardial myocardial blood flow (MBF) reduction, the hallmark of ischemia. The purpose of this study was to test the hypothesis that adenosine stress / rest 256x0.5mm MDCT can detect ischemia by measuring differences in subendo-cardial versus subepicardial MBF. Methods: Nineteen patients with abnormal SPECT perfusion studies underwent adenosine (140μg/kg/min) stress 256x0.5mm MDCT perfusion imaging (CTP): 120kV, 100mAs, 3 gantry rotations at 0.5 secs, followed by rest 256x0.5mm MDCT angiography (CTA): 120kV, 175mAs, 3 gantry rotations at 0.5 secs. CT perfusion images were reconstructed in the short axis with a 3 mm slice thickness. Endocardial and epicardial borders were defined, myocardium was sectored according to the standard 17 segment model, and divided circumferentially into endocardial and epicardial layers. The transmural perfusion ratio (TPR) was calculated by dividing the endocardial attenuation density (AD) by the epicardial AD in each sector. Ischemia was defined as TPR <0.8 in more than one sector. The TPR results were compared to the presence or absence of stenoses ≥50% on CTA and perfusion deficits on SPECT. Results: Mean TPR in abnormal and normal sectors was 0.71±0.05 and 1.01±0.06, respectively (p<0.01). Mean number of abnormal sectors for patients with no stenoses, 1-vessel, and multi-vessel disease were 1.6, 2.5, and 6.3; respectively (p<0.05). The sensitivity and specificity of TPR for detecting a stenosis ≥50% severity was 62% and 86% compared with 62% and 71% for SPECT (NS). When defining territorial ischemia as a SPECT perfusion abnormality plus a stenosis ≥50%, the sensitivity, specificity, positive and negative predictive values were 75%, 95%, 75%, and 95% for combined CTA/CTP imaging, respectively. Conclusions: The transmural perfusion ratio measured from 256x0.5mm MDCT perfusion images can detect the presence of obstructive atherosclerosis with similar accuracy compared with SPECT imaging. The combination of 256x0.5mm MDCT angiography and perfusion imaging may avoid the high false positive rate seen with SPECT imaging alone as well as improve its prediction of territorial ischemia.


2021 ◽  
Vol 2021 ◽  
pp. 1-13
Author(s):  
Yanjiao Li ◽  
Zhipeng Liu ◽  
Baojin Wu ◽  
Jingrui Zhang ◽  
Chao Li

The incidence rate of cerebrovascular diseases is increasing year by year, but the accuracy of clinical diagnosis is not high enough to cause disease. Many patients cannot effectively diagnose and treat the disease at the early stage. CT perfusion imaging (CTP) and CT angiography (CTA) were used to diagnose cerebrovascular diseases. In this paper, 26 cases of patients with acute cerebrovascular disease in our hospital from June to August 2020 were selected as the research objects. According to the diagnosis method voluntarily chosen by patients, 6 cases were only detected by CT perfusion imaging, 8 cases were only detected by CT angiography, and the remaining 12 cases were diagnosed by CT perfusion imaging and CT angiography. Then, according to the diagnosis results of the CT image of the patients with cerebrovascular disease, these samples were followed up after 3 months, 6 months, and 9 months, and more accurate diagnosis results were obtained. The study showed that, after 3 months of CT detection, the sensitivity of patients with CTP detection was 67%, that of patients with CTA detection was 72%, and that of patients with combined detection was 83%. After 6 months of CT detection, the sensitivity of patients with CTP detection was 75%, that of patients with CTA detection was 79%, and that of patients with combined detection was 93%. After 9 months of CT detection, the sensitivity of patients with CTP detection was 86%, that of patients with CTA detection was 89%, and that of patients with combined detection was 99%. Therefore, the use of CTA combined with CTP joint detection of acute cerebrovascular disease imaging technology can effectively improve the diagnostic accuracy of patients.


Sign in / Sign up

Export Citation Format

Share Document