Long-term Retention of Implicitly Acquired Learning in Patients with Alzheimer's Disease

the goal of this study is to assess whether new lyrics are better learned and memorized when presented in a spoken or sung form. In normal young adults, mixed results have been reported, with studies showing a positive, a negative, or a null effect of singing on verbal recall. Several factors can account for this limited aid of music. First, the familiarity of the melody might play a role. Second, successive learning sessions and long-term retention intervals may be necessary. These two factors are considered here in a case study of a participant who suffers from mild Alzheimer's disease. As expected, initial learning of new lyrics showed better performance for the spoken condition over the sung version unless the lyrics are learned on a familiar melody. After repeated learning episodes, learning sung lyrics – even on an unfamiliar melody – led to better retention of words. Thus, music may provide a more robust aid for consolidation in memory than spoken lyrics alone. The therapeutic implications of these results are discussed.

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Long-term retention is greater following closed-book tests than open-book tests

PsycEXTRA Dataset ◽

10.1037/e527352012-770 ◽

2006 ◽

Author(s):

Pooja K. Agarwal ◽

Jeffrey D. Karpicke ◽

Sean H. Kang ◽

Henry L. Roediger ◽

Kathleen B. McDermott

Keyword(s):

Open Book ◽

Term Retention ◽

Long Term Retention

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The Relative Potency of Study and Test Trials in Enhancing Long-Term Retention

PsycEXTRA Dataset ◽

10.1037/e633262013-206 ◽

2013 ◽

Cited By ~ 1

Author(s):

Henry L. Roediger ◽

John F. Nestojko

Keyword(s):

Relative Potency ◽

Term Retention ◽

Long Term Retention

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Long-Term Retention of Conditioned Aversion to Colored Water in Bobwhite Quail

PsycEXTRA Dataset ◽

10.1037/e665992011-302 ◽

1973 ◽

Author(s):

Hardy C. Wilcoxon ◽

James E. Dwyer

Keyword(s):

Conditioned Aversion ◽

Bobwhite Quail ◽

Term Retention ◽

Long Term Retention

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Retrieval practice promotes long-term retention irrespective of the placement

10.31234/osf.io/dk63q ◽

2020 ◽

Author(s):

alice latimier ◽

Arnaud Rierget ◽

Son Thierry Ly ◽

Franck Ramus

Keyword(s):

Retention Interval ◽

Retrieval Practice ◽

Memory Retention ◽

Term Retention ◽

Long Term Retention

The current study aimed at comparing the effect of three placements of the re-exposure episodes on memory retention (interpolated-small, interpolated-medium, postponed), depending on whether retrieval practice or re-reading was used, and on retention interval (one week vs one month).

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Faculty Opinions recommendation of Repeated simulation-based training for performing general anesthesia for emergency cesarean delivery: long-term retention and recurring mistakes.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718511906.793501803 ◽

2014 ◽

Author(s):

Philip Popham ◽

Sian Griffiths

Keyword(s):

General Anesthesia ◽

Cesarean Delivery ◽

Term Retention ◽

Emergency Cesarean ◽

Simulation Based ◽

Long Term Retention

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Integrated Biomarkers for Depression in Alzheimer’s Disease: A Critical Review

Current Alzheimer Research ◽

10.2174/1567205013666160603011256 ◽

2017 ◽

Vol 14 (4) ◽

pp. 441-452 ◽

Cited By ~ 4

Author(s):

Sofia Wenzler ◽

Christian Knochel ◽

Ceylan Balaban ◽

Dominik Kraft ◽

Juliane Kopf ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Affect Regulation ◽

Current Evidence ◽

Diagnostic Process ◽

Neuropsychiatric Manifestation ◽

The Brain ◽

Control Functional

Depression is a common neuropsychiatric manifestation among Alzheimer’s disease (AD) patients. It may compromise everyday activities and lead to a faster cognitive decline as well as worse quality of life. The identification of promising biomarkers may therefore help to timely initiate and improve the treatment of preclinical and clinical states of AD, and to improve the long-term functional outcome. In this narrative review, we report studies that investigated biomarkers for AD-related depression. Genetic findings state AD-related depression as a rather complex, multifactorial trait with relevant environmental and inherited contributors. However, one specific set of genes, the brain derived neurotrophic factor (BDNF), specifically the Val66Met polymorphism, may play a crucial role in AD-related depression. Regarding neuroimaging markers, the most promising findings reveal structural impairments in the cortico-subcortical networks that are related to affect regulation and reward / aversion control. Functional imaging studies reveal abnormalities in predominantly frontal and temporal regions. Furthermore, CSF based biomarkers are seen as potentially promising for the diagnostic process showing abnormalities in metabolic pathways that contribute to AD-related depression. However, there is a need for standardization of methodological issues and for replication of current evidence with larger cohorts and prospective studies.

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