THE DEVELOPMENT OF STRUCTURE AND FUNCTION IN THE POSTNATAL HUMAN CEREBRAL CORTEX FROM BIRTH TO 72 MONTHS: CHANGES IN THICKNESS OF LAYERS II AND III CO-RELATE TO THE ONSET OF NEW AGE-SPECIFIC BEHAVIORS

2002 ◽  
Vol 21 (3) ◽  
pp. 321-342 ◽  
Author(s):  
B. H. Landing ◽  
W. R. Shankle ◽  
J. Hara ◽  
J. Brannock ◽  
J. H. Fallon
Keyword(s):  
Cerebral Cortex ◽  
New Age ◽  
Structure And Function ◽  
Human Cerebral Cortex ◽  
And Function

Normal ageing and the brain

1998 ◽  
Vol 15 (1) ◽  
pp. 26-28
Author(s):  
CS Breathnach
Keyword(s):  
Cerebral Cortex ◽  
Imaging Techniques ◽  
Structure And Function ◽  
Ageing Population ◽  
Cell Shrinkage ◽  
Ageing Processes ◽  
Normal Ageing ◽  
And Function ◽  
Ageing Brain ◽  
The Brain

AbstractInterest in the psychiatric aspects of old age predated the institution of geriatrics as a clinical discipline, but the systematic study of the ageing brain only began in the second half of this century when an ageing population presented a global numerical challenge to society. In the senescent cerebral cortex, though the number of neurons is not reduced, cell shrinkage results in synaptic impoverishment with consequent cognitive impairment. Recent advances in imaging techniques, combined with burgeoning knowledge of neurobiological structure and function, have increased our understanding of the ageing processes in the human brain and permit an optimistic approach in the application of the newer insights into neuropsychology and geriatric psychiatry.

scholarly journals Neurodevelopmental Changes in Excitatory Synaptic Structure and Function in the Cerebral Cortex of Sanfilippo Syndrome IIIA Mice

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Chrissa A. Dwyer ◽  
Samantha L. Scudder ◽  
Ying Lin ◽  
Lara E. Dozier ◽  
Dustin Phan ◽  
...  
Keyword(s):  
Cerebral Cortex ◽  
Structure And Function ◽  
Sanfilippo Syndrome ◽  
Synaptic Structure ◽  
And Function

scholarly journals Importance of brain alterations in spinal cord injury

2021 ◽  
Vol 104 (3) ◽  
pp. 003685042110311
Author(s):  
Can Zhao ◽  
Shu-Sheng Bao ◽  
Meng Xu ◽  
Jia-Sheng Rao
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Cerebral Cortex ◽  
Information Flow ◽  
Brain Structure ◽  
Structure And Function ◽  
Cord Injury ◽  
Brain Structure And Function ◽  
And Function ◽  
The Brain

Spinal cord injury (SCI) destroys the sensorimotor pathway and blocks the information flow between the peripheral nerve and the brain, resulting in autonomic function loss. Numerous studies have explored the effects of obstructed information flow on brain structure and function and proved the extensive plasticity of the brain after SCI. Great progress has also been achieved in therapeutic strategies for SCI to restore the “re-innervation” of the cerebral cortex to the limbs to some extent. Although no thorough research has been conducted, the changes of brain structure and function caused by “re-domination” have been reported. This article is a review of the recent research progress on local structure, functional changes, and circuit reorganization of the cerebral cortex after SCI. Alterations of structure and electrical activity characteristics of brain neurons, features of brain functional reorganization, and regulation of brain functions by reconfigured information flow were also explored. The integration of brain function is the basis for the human body to exercise complex/fine movements and is intricately and widely regulated by information flow. Hence, its changes after SCI and treatments should be considered.

scholarly journals Development and function of human cerebral cortex neural networks from pluripotent stem cells in vitro

Development ◽  
2015 ◽  
Vol 142 (18) ◽  
pp. 3178-3187 ◽  
Author(s):  
P. Kirwan ◽  
B. Turner-Bridger ◽  
M. Peter ◽  
A. Momoh ◽  
D. Arambepola ◽  
...  
Keyword(s):  
Neural Networks ◽  
Stem Cells ◽  
Cerebral Cortex ◽  
Pluripotent Stem Cells ◽  
Human Cerebral Cortex ◽  
And Function
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