Predictor variables of neurodevelopmental characteristics at 2 years among low birth weight and preterm children: a 2-year follow-up study

The aim of this long-term longitudinal study in Taiwan was to estimate and compare the prevalence of cerebral palsy (CP) and to identify the age of CP diagnosis of term-born and preterm children with different birthweights. Records of 1494 extremely low birth weight (ELBW, <1000 g), 3961 very low birth weight (VLBW, 1000–1499 g), 19,612 low birth weight (LBW, 1500–2499 g) preterm, and 100,268 matched term-born children were retrieved from Taiwan′s National Health Insurance Research Database. According to a 12-year retrospective data review, the results showed the highest prevalence of CP in preterm ELBW children (147.3 cases per 1000 neonatal survivors), followed by preterm VLBW (97.2 cases), preterm LBW (27.7 cases), with the lowest prevalence in term-born children (2.5 cases). Regardless of the birthweight group, 90% of preterm children with CP were diagnosed by 4 years of age, but it was 7 years before 90% of term-born children with CP were diagnosed. After removing the children whose CP was caused by brain infections, injuries, or cerebrovascular accidents after 4 months of age, there were similar mean ages at the initial CP diagnosis (1.58–1.64 years of age) across birthweight groups born prematurely, but initial diagnosis occurred at an older age (2.41 years of age) in term-born children. The results indicate that birthweight is reversely correlated with the prevalence of CP in preterm children. Although the three preterm birthweight groups received different types of developmental follow-up programs after birth, it did not influence their age at the initial diagnosis of CP. Furthermore, we suggest that follow-up for at least 4 years after birth for preterm children, and 7 years for term-born children, is optimal for estimating CP prevalence. In order to identify and provide early intervention for term-born children with CP earlier, it is suggested that parents routinely fill out a self-reported motor developmental screening questionnaire and pediatricians conduct a motor developmental examination on term-born children at each time of scheduled vaccination injections.

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A National Short-Term Follow-Up Study of Extremely Low Birth Weight Infants Born in Finland in 1996-1997

PEDIATRICS ◽

10.1542/peds.107.1.e2 ◽

2001 ◽

Vol 107 (1) ◽

pp. e2-e2 ◽

Cited By ~ 79

Author(s):

V. Tommiska ◽

K. Heinonen ◽

S. Ikonen ◽

P. Kero ◽

M.-L. Pokela ◽

...

Keyword(s):

Birth Weight ◽

Low Birth Weight ◽

Extremely Low Birth Weight ◽

Short Term ◽

Low Birth Weight Infants ◽

Follow Up Study

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A Six-Months' Follow-Up Study of Growth, Morbidity and Functional Immunity in Low Birth Weight Neonates with Special Reference to Intrauterine Growth Retardation in Small-for-Gestational-Age Infants

Journal of Tropical Pediatrics ◽

10.1093/tropej/29.5.278 ◽

1983 ◽

Vol 29 (5) ◽

pp. 278-282 ◽

Cited By ~ 11

Author(s):

K. SAHA ◽

P. KAUR ◽

G. SRIVASTAV ◽

D. S. CHAUDHURY

Keyword(s):

Birth Weight ◽

Low Birth Weight ◽

Gestational Age ◽

Growth Retardation ◽

Small For Gestational Age ◽

Intrauterine Growth Retardation ◽

Intrauterine Growth ◽

Follow Up Study ◽

Functional Immunity

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Morbidity and Mortality Pattern of Preterm Low Birth Weight Neonates Admitted in Amhara Region Refferal Hospitals of Ethiopia Retrospective Follow-Up Study

10.21203/rs.3.rs-508365/v1 ◽

2021 ◽

Author(s):

Belete Fenta Kebede ◽

Yalemtsedhay Dagnaw Genie ◽

Mulualem Silesh Zerihun ◽

Desalew Tilahun Beyene

Keyword(s):

Congenital Anomaly ◽

Birth Weight ◽

Low Birth Weight ◽

Morbidity And Mortality ◽

Public Health Issue ◽

Amhara Region ◽

Mortality Pattern ◽

Follow Up Study ◽

Referral Hospitals

Abstract Introduction: Being born preterm low birth weight was found as the main risk factor for neonatal mortality and development of different morbidities. Even though prevalence of preterm low birth weight neonates is high. There is information gap about prevalence of their morbidity and mortality pattern in this study area. Objective This study was conducted to assess morbidity and mortality pattern of preterm low birth weight neonates admitted in Amhara region referral hospitals of Ethiopia. Methodology: Retrospective follow up study was conducted on preterm low birth weight neonates admitted in Amhara region referral hospital between January 01 /2017 and December 30 /2018. Data were entered to Epi- data 4.4.2.1 and exported to STATA 14 for cleaning and analysis. Logistic regression model was used to analyze the data. Result This study revealed that 37.8 %( 95%CI: 32.4–43.5) participants were died. The most common morbidities found in preterm low birth neonates was 219 (75.26%) hypothermia followed by 201(69.07%), 145(49.83%), 39(13.4%) and 24(8.25%) with sepsis, RDS, jaundice, congenital anomaly morbidities respectively. Sepsis (AOR: 2.06(95% CI: 1.05–4.02), RDS (AOR: 3.28 (95% CI: 1.81–5.95), congenital abnormality (AOR: 3.14(95%CI: 1.16–8.54), hypoglycemia (AOR 3.81(95%CI: 1.27–11.44) were independent factors of mortality Conclusion In this study, mortality of preterm low birth neonatal was higher and public health issue. Hypothermia, Sepsis, RDS, jaundice and congenital anomaly were common morbidities. Sepsis, respiratory distress, hypoglycemia and congenital anomaly were factors of mortality.

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OESTRIOL EXCRETION IN PREGNANT DIABETICS RELATED TO LONG-TERM PROGNOSIS OF SURVIVING CHILDREN

Acta Endocrinologica ◽

10.1530/acta.0.075s095 ◽

1974 ◽

Vol 77 (3_Suppl) ◽

pp. S95-S104 ◽

Cited By ~ 7

Author(s):

Minna Yssing

Keyword(s):

Birth Weight ◽

Low Birth Weight ◽

Congenital Malformations ◽

Perinatal Complications ◽

Perinatal Factors ◽

Follow Up Study ◽

Significant Difference ◽

Long Term Prognosis

ABSTRACT Urinary 24-hour oestriol excretion in pregnant diabetics were studied in 154 pregnancies resulting in 158 surviving children. Subnormal oestriol levels were found in 33 pregnancies associated with low birth weight, but otherwice widely independent on pre- and perinatal factors. Results of follow-up study of the complete infant material at ages varying from 1 8/12 to 10 1/12 years were related to maternal oestriol excretion levels in relevant pregnancies. The incidence of children with major abnormalities in the subnormal oestriol group (39.4 %) was significantly higher (P < 0.01) than in the normal oestriol group (16.0 %). The incidence of cerebral damaged children in the subnormal oestriol group (51.5%) was significantly higher (P <0.01) than in the normal oestriol group (22.4 %). There was no significant difference in distribution of congenital malformations. Correlations of maternal White class, pre- and perinatal complications and birth weight with oestriol levels and results of follow-up study reflected the distribution in the total series with higher incidence of abnormal children in the subnormal oestriol fractions.

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