Homology Modelling of the Ligand Binding Domain of Mineralocorticoid Receptor: Close Structural Kinship with Glucocorticoid Receptor Ligand Binding Domain and their Similar Binding Mode with DOC (de-oxy corticosterone)

2002 ◽  
Vol 20 (1) ◽  
pp. 21-29 ◽  
Author(s):  
Raja Dey ◽  
P. Roychowdhury
Keyword(s):  
Glucocorticoid Receptor ◽  
Ligand Binding ◽  
Mineralocorticoid Receptor ◽  
Homology Modelling ◽  
Binding Mode ◽  
Binding Domain ◽  
Ligand Binding Domain ◽  
Receptor Ligand

Enhancing the Stability and Solubility of the Glucocorticoid Receptor Ligand-Binding Domain by High-Throughput Library Screening

2010 ◽  
Vol 403 (4) ◽  
pp. 562-577 ◽  
Author(s):  
Tobias Seitz ◽  
Ralf Thoma ◽  
Guillaume A. Schoch ◽  
Martine Stihle ◽  
Jörg Benz ◽  
...  
Keyword(s):  
Glucocorticoid Receptor ◽  
Ligand Binding ◽  
High Throughput ◽  
Binding Domain ◽  
Ligand Binding Domain ◽  
Library Screening ◽  
Receptor Ligand ◽  
The Stability

scholarly journals Crystal Structure of the Glucocorticoid Receptor Ligand Binding Domain Reveals a Novel Mode of Receptor Dimerization and Coactivator Recognition

Cell ◽  
2002 ◽  
Vol 110 (1) ◽  
pp. 93-105 ◽  
Author(s):  
Randy K. Bledsoe ◽  
Valerie G. Montana ◽  
Thomas B. Stanley ◽  
Chris J. Delves ◽  
Christopher J. Apolito ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Glucocorticoid Receptor ◽  
Ligand Binding ◽  
Binding Domain ◽  
Ligand Binding Domain ◽  
Receptor Ligand ◽  
Receptor Dimerization

scholarly journals A Natural Mutation in Helix 5 of the Ligand Binding Domain of Glucocorticoid Receptor Enhances Receptor-Ligand Interaction

PLoS ONE ◽  
2016 ◽  
Vol 11 (10) ◽  
pp. e0164628 ◽  
Author(s):  
Henry Reyer ◽  
Siriluck Ponsuksili ◽  
Ellen Kanitz ◽  
Ralf Pöhland ◽  
Klaus Wimmers ◽  
...  
Keyword(s):  
Glucocorticoid Receptor ◽  
Ligand Binding ◽  
Binding Domain ◽  
Ligand Binding Domain ◽  
Ligand Interaction ◽  
Receptor Ligand ◽  
Natural Mutation
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