End-tidal carbon monoxide measurements in infant respiratory distress syndrome

Abstract Background Inhalation injury from smoke or chemical products and carbon monoxide poisoning are major causes of death in burn patients from fire accidents. Respiratory tract injuries from inhalation injury and carbon monoxide poisoning can lead to acute respiratory distress syndrome and cytokine storm syndrome. In the case of acute respiratory failure needing mechanical ventilation accompanied by cytokine storm, mortality is high and immediate adequate treatment at the emergency department is very important. Case presentation This report describes a case of acute respiratory distress syndrome and cytokine storm followed by carbon monoxide poisoning in a 34-year-old Korean male patient who was in a house fire, and was successfully treated by extracorporeal membrane oxygenation and direct hemoperfusion with polymyxin B-immobilized fiber column at emergency department. Conclusions To prevent mortality in acute respiratory distress syndrome with cytokine storm from inhalation injury and to promote a better prognosis, we suggest that early implication of extracorporeal membranous oxygenation along with direct hemoperfusion with polymyxin B-immobilized fiber column even at the emergency department should be considered.

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End-Tidal-to-Arterial PCO2 Ratio as Signifier for Physiologic Dead-Space Ratio and Oxygenation Dysfunction in Acute Respiratory Distress Syndrome

Respiratory Care ◽

10.4187/respcare.08061 ◽

2020 ◽

pp. respcare.08061

Author(s):

Richard H Kallet ◽

Michael S Lipnick

Keyword(s):

Acute Respiratory Distress Syndrome ◽

Respiratory Distress Syndrome ◽

Respiratory Distress ◽

Dead Space ◽

Distress Syndrome ◽

Arterial Pco2 ◽

Physiologic Dead Space ◽

End Tidal ◽

Space Ratio

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Age dependence of serum β-N-acetylhexosaminidase (NAG) activity

Clinical Chemistry and Laboratory Medicine (CCLM) ◽

10.1515/cclm.2004.055 ◽

2004 ◽

Vol 42 (3) ◽

Cited By ~ 2

Author(s):

Anna V. Oláh ◽

Robert G. Price ◽

László Csáthy ◽

Éva Országh ◽

Éva Oláh ◽

...

Keyword(s):

Early Childhood ◽

Respiratory Distress Syndrome ◽

Respiratory Distress ◽

Necrotizing Enterocolitis ◽

Vascular Injury ◽

Distress Syndrome ◽

Reference Ranges ◽

Age Dependence ◽

Infant Respiratory Distress Syndrome ◽

Age Dependent

AbstractSerum N-acetyl-β-D-glucosaminidase (NAG; EC 3.2.1.30) is a hexosaminidase and may be a predictor of vascular injury, e.g., in infant respiratory distress syndrome, pneumonia, broncho-pulmonary dysplasia and necrotizing enterocolitis. To estimate the new diagnostic prospects we have modified our urinary NAG assay. In this sensitive colorimetric micro-assay, VRA-GlcNAc was used as a substrate. In the present study the age dependence of serum NAG activity was investigated in newborn babies, infants (1–24 months), children (2–18 years) and adults (19–80 years). Serum NAG activity was found to be age-dependent; it is higher in early childhood (11–59 U/l) but decreases to a constant value at the age of 1–2 years. After the age of 2 years it is similar to adults' NAG (10–30 U/l). In pediatrics age-matched reference ranges must be taken into consideration.

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Expectorant promising for treating infant respiratory distress syndrome

JAMA ◽

10.1001/jama.249.18.2425 ◽

1983 ◽

Vol 249 (18) ◽

pp. 2425-2426

Author(s):

J. Henahan

Keyword(s):

Respiratory Distress Syndrome ◽

Respiratory Distress ◽

Distress Syndrome ◽

Infant Respiratory Distress Syndrome

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Establishing a gradient between partial pressure of arterial carbon dioxide and end-tidal carbon dioxide in patients with acute respiratory distress syndrome

Journal of Investigative Medicine ◽

10.1136/jim-2016-000253 ◽

2016 ◽

Vol 65 (2) ◽

pp. 338-341 ◽

Cited By ~ 5

Author(s):

Tariq Yousuf ◽

Taylor Brinton ◽

Ghulam Murtaza ◽

Daniel Wozniczka ◽

Khansa Ahmad ◽

...

Keyword(s):

Carbon Dioxide ◽

Acute Respiratory Distress Syndrome ◽

Respiratory Distress Syndrome ◽

Respiratory Distress ◽

Distress Syndrome ◽

Statistical Significance ◽

End Tidal Carbon Dioxide ◽

The Mean ◽

The Difference ◽

End Tidal

End-tidal carbon dioxide (ETCO2) monitoring is useful in many situations. However, ETCO2 monitoring is unreliable in patients with acute respiratory distress syndrome (ARDS) due to widespread lung inflammation. In our study, we attempt to establish the gradient between the arterial pressure of carbon dioxide (PaCO2) and ETCO2 in patients with ARDS, which we defined as the PaETCO2 gradient. The main objective of the study was to establish a PaETCO2 gradient in each severity of ARDS. We analyzed 35 patients with ARDS and a total of 88 arterial blood gases were included. PaCO2, PaO2/FiO2 and ETCO2 were measured. Patients were stratified into mild, moderate and severe ARDS as classified by the Berlin ARDS criteria. PaCO2 and ETCO2 were compared at each severity stratification. The mean PaCO2 was 50.0, the mean ETCO2 was 26.6 and the gradient among all samples was 23.24 (±12.02). The mean gradient for each severity is as follows: mild: 19.3 (±9.9), moderate: 27.9 (±13.2) and severe: 23.9 (±7.8). The difference between the PaETCO2 gradient of the mild to moderate (p=0.001) and mild to severe groups (p=0.01) reached statistical significance. However, the difference between the moderate to severe groups did not reach statistical significance (p=0.48). We found the gradient between PaCO2 and ETCO2 in patients with ARDS is vast and tends to worsen with increasing severity of ARDS. This indicates that the gradient between the 2 may be used as an indicator of increasing severity of ARDS.

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