Influence of Modic Changes on Cage Subsidence and Intervertebral Fusion after Single-Level Anterior Cervical Corpectomy and Fusion

Author(s):  
Jia Li ◽  
Jingtao Zhang ◽  
Tong Tong ◽  
Yong Shen
2021 ◽  
Author(s):  
Yifan Tang ◽  
Fengning Li ◽  
Xiangwu Geng ◽  
Lianshun Jia ◽  
Shengyuan Zhou ◽  
...  

Abstract Background: To analyze risk factors of titanium mesh cage (TMC) subsidence in single-level anterior cervical corpectomy and fusion (ACCF) for cervical ossification of the posterior longitudinal ligament (OPLL). Methods: Patients with cervical OPLL who were treated with single-level ACCF between January 2019 to December 2019 were retrospectively analyzed in two groups: patients with TMC subsidence as Group S, and patients with no TMC subsidence as Group N during the one-year follow-up period. The degree of distraction between decompression of the vertebral bodies and correction of the cervical curvature was measured to analyze their relationship with TMC subsidence. Results: There was no significant difference in patient demographics and complications between the two groups. The degree of distraction in Group S was significantly higher than that in Group N. The change of C2 to C7 Cobb angle (α) in Group S was significantly greater than that in Group N, and the interspinous process distance (SPD) in Group S was also significantly greater than that in Group N. The JOA score and JOA recovery rate were not statistically different between the two groups.Conclusions: Intraoperative selection of overlength TMC in single-level ACCF for OPLL, over-distraction, and excessive correction of the cervical curvature may cause TMC subsidence after surgery. No significant impact of TMC subsidence on the surgical outcome was observed during the 1-year follow-up period.


2015 ◽  
Vol 2015 ◽  
pp. 1-6
Author(s):  
Hui Xu ◽  
Xiaofeng Ren ◽  
Dawei Wang ◽  
Yongfei Zhao ◽  
Yan Wang ◽  
...  

Purpose. This study was to report the clinical use of biomimetic nanohydroxyapatite/polyamide 66 (n-HA/PA 66) mesh cages in anterior cervical corpectomy and fusion (ACCF) surgery.Method. 95 patients who underwent single level anterior cervical corpectomy and fusion for cervical spondylosis myelopathy (CSM) in our hospital were reviewed and divided into 2 groups according to using nanohydroxyapatite/polyamide mesh cage and titanium mesh cage (TMC). Demographic data of patients and surgical, clinical, and radiological data before operation and at last follow-up were collected and compared.Result. The operation time, surgical blood loss, complications, and Japanese Orthopaedic Association scores (JOA scores) of two groups were similar. At the last follow-up both the two groups obtained 100% solid bone fusion, but the TMC group had higher rate of severe cage subsidence than the n-HA/PA 66 group (27% versus 2%).Conclusion. Nanohydroxyapatite/polyamide 66 mesh cage is safe and effective in ACCF and can be a substitution to titanium mesh cage.


2020 ◽  
Vol 20 (1) ◽  
pp. 8-17
Author(s):  
Charles Tatter ◽  
Oscar Persson ◽  
Gustav Burström ◽  
Erik Edström ◽  
Adrian Elmi-Terander

Abstract BACKGROUND Anterior cervical corpectomy and fusion (ACCF) is a treatment option for several cervical pathologies. Various graft materials such as autografts, titanium mesh cages (TMC), or poly-ether-ether-ketone (PEEK) cages are used. Additional posterior fixation (PF) to provide extra support and improve stability is sometimes performed initially, or later as supplementary treatment. OBJECTIVE To describe our retrospective study of 119 consecutive cases of ACCF with synthetic grafts, in 3 cohorts of cervical spondylotic myelopathy (CSM), infectious and neoplastic processes, and trauma, with special focus on need for supplementary PF. METHODS A total of 135 adult patients treated with ACCF between January 2005 and January 2018 were identified. Patients lost to follow-up were excluded, and 119 remaining patients were included for retrospective clinical and radiological assessment. RESULTS Synthetic grafts were used in 116 (97%) cases. Only 9 (8%) ACCF cases required later supplementary PF, where 7 (78%) cases were multilevel. There was a statistically significant difference in revision rate with PF for single-level compared to multilevel ACCFs (P = .001). Revision rates with PF were 2%, 29%, and 7% in CSM, infectious and neoplastic processes, and trauma cohorts, respectively. CONCLUSION The results indicate that ACCF is a safe and effective treatment for degenerative and traumatic cervical spine disorders, with low complication and revision rates. Single-level ACCF can be performed without additional PF. Multilevel ACCF (n > 2) and pathologies affecting bone quality seem to be risk factors for material subsidence and instability. In these cases, additional PF should be considered.


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