Poly (ADP-ribose) polymerase inhibitors sensitize cancer cells to hypofractionated radiotherapy through altered selection of DNA double-strand break repair pathways

2021 ◽  
pp. 1-27
Author(s):  
Yuji Seo ◽  
Keisuke Tamari ◽  
Yutaka Takahashi ◽  
Kazumasa Minami ◽  
Shotaro Tatekawa ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Strand Break ◽  
Double Strand Break ◽  
Double Strand Break Repair ◽  
Hypofractionated Radiotherapy ◽  
Polymerase Inhibitors ◽  
Dna Double Strand Break ◽  
Repair Pathways ◽  
Break Repair ◽  
Selection Of

scholarly journals MEK inhibitor GSK1120212-mediated radiosensitization of pancreatic cancer cells involves inhibition of DNA double-strand break repair pathways

Cell Cycle ◽  
2015 ◽  
Vol 14 (23) ◽  
pp. 3713-3724 ◽  
Author(s):  
Adriana Estrada-Bernal ◽  
Moumita Chatterjee ◽  
S Jaharul Haque ◽  
Linlin Yang ◽  
Meredith A Morgan ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Cancer Cells ◽  
Mek Inhibitor ◽  
Strand Break ◽  
Double Strand Break ◽  
Double Strand Break Repair ◽  
Pancreatic Cancer Cells ◽  
Dna Double Strand Break ◽  
Repair Pathways ◽  
Break Repair

scholarly journals DNA double-strand break repair efficiency in cancer cells exposed to laser-driven ultrashort electron beams

2021 ◽  
Author(s):  
Andreyan Osipov ◽  
Nelly Babayan ◽  
Natalia Vorobyeva ◽  
Bagrat Grigoryan ◽  
Anna Chigasova-Grekhova ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Electron Beams ◽  
Strand Break ◽  
Double Strand Break ◽  
Double Strand Break Repair ◽  
Dna Double Strand Break ◽  
Repair Efficiency ◽  
Break Repair

scholarly journals Mycobacteria exploit three genetically distinct DNA double-strand break repair pathways

2010 ◽  
Vol 79 (2) ◽  
pp. 316-330 ◽  
Author(s):  
Richa Gupta ◽  
Daniel Barkan ◽  
Gil Redelman-Sidi ◽  
Stewart Shuman ◽  
Michael S. Glickman
Keyword(s):  
Strand Break ◽  
Double Strand Break ◽  
Double Strand Break Repair ◽  
Dna Double Strand Break ◽  
Repair Pathways ◽  
Break Repair

scholarly journals Resveratrol modulates DNA double-strand break repair pathways in an ATM/ATR–p53- and –Nbs1-dependent manner

2008 ◽  
Vol 29 (3) ◽  
pp. 519-527 ◽  
Author(s):  
Susanne Andrea Gatz ◽  
Marlen Keimling ◽  
Cindy Baumann ◽  
Thilo Dörk ◽  
Klaus-Michael Debatin ◽  
...  
Keyword(s):  
Strand Break ◽  
Double Strand Break ◽  
Double Strand Break Repair ◽  
Dependent Manner ◽  
Dna Double Strand Break ◽  
Repair Pathways ◽  
Break Repair

scholarly journals Chemotherapeutic Compounds Targeting the DNA Double-Strand Break Repair Pathways: The Good, the Bad, and the Promising

2014 ◽  
Vol 4 ◽  
Author(s):  
Christian Jekimovs ◽  
Emma Bolderson ◽  
Amila Suraweera ◽  
Mark Adams ◽  
Kenneth J. O’Byrne ◽  
...  
Keyword(s):  
Strand Break ◽  
Double Strand Break ◽  
Double Strand Break Repair ◽  
Dna Double Strand Break ◽  
Repair Pathways ◽  
Break Repair
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