Environmental tobacco smoke and its effect on the symptoms and medication in children with asthma

2009 ◽  
Vol 19 (2) ◽  
pp. 97-108 ◽  
Author(s):  
Akira Yamasaki ◽  
Keichi Hanaki ◽  
Katsuyuki Tomita ◽  
Masanari Watanabe ◽  
Yasuyuki Hasagawa ◽  
...  
2008 ◽  
Vol 8 (5) ◽  
pp. 288-293 ◽  
Author(s):  
Maria Fagnano ◽  
Kelly M. Conn ◽  
Jill S. Halterman

CHEST Journal ◽  
2001 ◽  
Vol 120 (5) ◽  
pp. 1709-1722 ◽  
Author(s):  
Sandra R. Wilson ◽  
Eileen G. Yamada ◽  
Reddivalam Sudhakar ◽  
Lauro Roberto ◽  
David Mannino ◽  
...  

1998 ◽  
Vol 95 (2) ◽  
pp. 143 ◽  
Author(s):  
Jean-Christophe DUBUS ◽  
Christiane ODDOZE ◽  
Monique BADIER ◽  
Chantal GUILLOT ◽  
Bernard BRUGUEROLLE

PEDIATRICS ◽  
2008 ◽  
Vol 122 (6) ◽  
pp. 1277-1283 ◽  
Author(s):  
J. S. Halterman ◽  
B. Borrelli ◽  
P. Tremblay ◽  
K. M. Conn ◽  
M. Fagnano ◽  
...  

1998 ◽  
Vol 95 (2) ◽  
pp. 143-149 ◽  
Author(s):  
Jean-Christophe DUBUS ◽  
Christiane ODDOZE ◽  
Monique BADIER ◽  
Chantal GUILLOT ◽  
Bernard BRUGUEROLLE

1.The aim of the study was to determine the carbachol and albuterol responsiveness in treated and untreated asthmatic and allergic children exposed to environmental tobacco smoke assessed by urinary cotinine measurements. 2.Forty-six asthmatic and allergic children with normal spirometric values were recruited. The doubling dose, concentration of carbachol producing a 2-fold increase in specific airway resistance (SRaw) was determined and 200 ;μg of albuterol were administered via a Volumatic® spacer. The percentage of bronchodilatation was defined as the difference between the largest obtained SRaw and the post-β2 SRaw divided by the largest SRaw. Data were compared by a Mann–Whitney U-test. 3.The 23 children with a high urinary cotinine, compared with the 23 children without urinary cotinine, had a decreased doubling dose (108.2±14.7 ;μg versus 160.9±19.5 ;μg; P = 0.04) and an increased percentage of bronchodilatation (74.8±1.4% versus 68.8±1.8%; P = 0.03). A prophylactic anti-inflammatory treatment induced a weaker bronchial reactivity to carbachol and a slightly greater bronchodilatation in children exposed to environmental tobacco smoke. 4.Environmental tobacco smoke increases bronchial reactivity in asthmatic and allergic children. This effect might be reduced by anti-inflammatory therapy. The bronchodilator response may be enhanced in exposed children and may be caused by one or several direct interactions between tobacco smoke compounds and albuterol.


2020 ◽  
Vol 41 (3) ◽  
pp. 198-203
Author(s):  
M. Bobrowska-Korzeniowska ◽  
J. Jerzyńska ◽  
M. Mitał ◽  
D. Podlecka ◽  
A. Brzozowska ◽  
...  

Background: Interventions to help parents quit smoking may yield important benefits for children with asthma. Children’s exposure to environmental tobacco smoke can be measured by reporting of an adult in the household and testing the child’s biomarker, e.g., cotinine. Objective: The aim of the study was to assess the effectiveness of “face-to-face” intervention carried out since 2016 in families with children diagnosed with asthma 3 years after beginning the anti-tobacco intervention. Methods: This study was a follow-up to an interventional study that assessed the effectiveness of direct patient education versus educational leaflets alone about parental tobacco smoking. The patients with asthma (ages 4‐17 years) enrolled in our original intervention study conducted in 2016 were under the care of the allergy outpatient clinic. The active group was individually educated about the harmful effects of environmental tobacco smoke on their children. The control group included patients and parents, among whom only leaflets were distributed. After 3 years of ongoing intervention, in patients from both groups, exposure to tobacco smoking was evaluated with a questionnaire addressed to parents and/or caregivers and measurement of cotinine in children’s urine. The forced expiratory volume in the first second of expiration and fractional exhaled nitric oxide levels were measured. Results: Seventy participants completed the study: 37 in the active group and 33 in the control group. In the active group, 27% of the parents quit smoking entirely compared with 9.4% of parents in the control group. In the group of active intervention, a significant decrease in the cotinine level (p < 0 .001) and the number of cigarettes smoked daily were observed (p < 0.001) 3 years after the active intervention compared with values right after the intervention. In the control group, there were no significant changes in the above-mentioned parameters. Conclusion: “Face-to-face” intervention among families with smokers were effective and lowered cotinine levels in children with asthma and the number of cigarettes smoked assessed 3 years after the intervention.


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