The basic reproduction number in some discrete-time epidemic models

2008 ◽  
Vol 14 (10-11) ◽  
pp. 1127-1147 ◽  
Author(s):  
Linda J.S. Allen ◽  
P. van den Driessche
PLoS ONE ◽  
2021 ◽  
Vol 16 (9) ◽  
pp. e0257598
Author(s):  
Willem Esterhuizen ◽  
Jean Lévine ◽  
Stefan Streif

We present a detailed set-based analysis of the well-known SIR and SEIR epidemic models subjected to hard caps on the proportion of infective individuals, and bounds on the allowable intervention strategies, such as social distancing, quarantining and vaccination. We describe the admissible and maximal robust positively invariant (MRPI) sets of these two models via the theory of barriers. We show how the sets may be used in the management of epidemics, for both perfect and imperfect/uncertain models, detailing how intervention strategies may be specified such that the hard infection cap is never breached, regardless of the basic reproduction number. The results are clarified with detailed examples.


2021 ◽  
Vol 2021 (1) ◽  
Author(s):  
Andrés Ríos-Gutiérrez ◽  
Soledad Torres ◽  
Viswanathan Arunachalam

AbstractIn this paper, we discuss the basic reproduction number of stochastic epidemic models with random perturbations. We define the basic reproduction number in epidemic models by using the integral of a function or survival function. We study the systems of stochastic differential equations for SIR, SIS, and SEIR models and their stability analysis. Some results on deterministic epidemic models are also obtained. We give the numerical conditions for which the disease-free equilibrium point is asymptotically stable.


2021 ◽  
Vol 2021 (1) ◽  
Author(s):  
Rafael Bravo de la Parra ◽  
Luis Sanz-Lorenzo

AbstractThe main aim of the work is to present a general class of two time scales discrete-time epidemic models. In the proposed framework the disease dynamics is considered to act on a slower time scale than a second different process that could represent movements between spatial locations, changes of individual activities or behaviors, or others.To include a sufficiently general disease model, we first build up from first principles a discrete-time susceptible–exposed–infectious–recovered–susceptible (SEIRS) model and characterize the eradication or endemicity of the disease with the help of its basic reproduction number $\mathcal{R}_{0}$ R 0 .Then, we propose a general full model that includes sequentially the two processes at different time scales and proceed to its analysis through a reduced model. The basic reproduction number $\overline{\mathcal{R}}_{0}$ R ‾ 0 of the reduced system gives a good approximation of $\mathcal{R}_{0}$ R 0 of the full model since it serves at analyzing its asymptotic behavior.As an illustration of the proposed general framework, it is shown that there exist conditions under which a locally endemic disease, considering isolated patches in a metapopulation, can be eradicated globally by establishing the appropriate movements between patches.


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