scholarly journals Discrete epidemic models with two time scales

2021 ◽  
Vol 2021 (1) ◽  
Author(s):  
Rafael Bravo de la Parra ◽  
Luis Sanz-Lorenzo

AbstractThe main aim of the work is to present a general class of two time scales discrete-time epidemic models. In the proposed framework the disease dynamics is considered to act on a slower time scale than a second different process that could represent movements between spatial locations, changes of individual activities or behaviors, or others.To include a sufficiently general disease model, we first build up from first principles a discrete-time susceptible–exposed–infectious–recovered–susceptible (SEIRS) model and characterize the eradication or endemicity of the disease with the help of its basic reproduction number $\mathcal{R}_{0}$ R 0 .Then, we propose a general full model that includes sequentially the two processes at different time scales and proceed to its analysis through a reduced model. The basic reproduction number $\overline{\mathcal{R}}_{0}$ R ‾ 0 of the reduced system gives a good approximation of $\mathcal{R}_{0}$ R 0 of the full model since it serves at analyzing its asymptotic behavior.As an illustration of the proposed general framework, it is shown that there exist conditions under which a locally endemic disease, considering isolated patches in a metapopulation, can be eradicated globally by establishing the appropriate movements between patches.

PLoS ONE ◽  
2021 ◽  
Vol 16 (9) ◽  
pp. e0257598
Author(s):  
Willem Esterhuizen ◽  
Jean Lévine ◽  
Stefan Streif

We present a detailed set-based analysis of the well-known SIR and SEIR epidemic models subjected to hard caps on the proportion of infective individuals, and bounds on the allowable intervention strategies, such as social distancing, quarantining and vaccination. We describe the admissible and maximal robust positively invariant (MRPI) sets of these two models via the theory of barriers. We show how the sets may be used in the management of epidemics, for both perfect and imperfect/uncertain models, detailing how intervention strategies may be specified such that the hard infection cap is never breached, regardless of the basic reproduction number. The results are clarified with detailed examples.


2021 ◽  
Vol 2021 (1) ◽  
Author(s):  
Andrés Ríos-Gutiérrez ◽  
Soledad Torres ◽  
Viswanathan Arunachalam

AbstractIn this paper, we discuss the basic reproduction number of stochastic epidemic models with random perturbations. We define the basic reproduction number in epidemic models by using the integral of a function or survival function. We study the systems of stochastic differential equations for SIR, SIS, and SEIR models and their stability analysis. Some results on deterministic epidemic models are also obtained. We give the numerical conditions for which the disease-free equilibrium point is asymptotically stable.


Filomat ◽  
2019 ◽  
Vol 33 (8) ◽  
pp. 2393-2408 ◽  
Author(s):  
Mahmood Parsamanesh ◽  
Saeed Mehrshad

A discrete-time SIS epidemic model with vaccination is presented and studied. The model includes deaths due to disease and the total population size is variable. First, existence and positivity of the solutions are discussed and equilibria of the model and basic reproduction number are obtained. Next, the stability of the equilibria is studied and conditions of stability are obtained in terms of the basic reproduction number R0. Also, occurrence of the fold bifurcation, the flip bifurcation, and the Neimark-Sacker bifurcation is investigated at equilibria. In addition, obtained results are numerically discussed and some diagrams for bifurcations, Lyapunov exponents, and solutions of the model are presented.


2019 ◽  
Vol 13 (01) ◽  
pp. 2050005
Author(s):  
Juliet N. Nakakawa ◽  
Joseph Y. T. Mugisha ◽  
Michael W. Shaw ◽  
Eldad Karamura

In this paper, we study a deterministic model with non-autonomous system for mixed cultivars to assess the effect of cultivar susceptibility and seasonal variation on banana Xanthomonas wilt (BXW) disease dynamics. A special case of two cultivars classified as highly susceptible for inflorescence infection (ABB) and less susceptible (AAA) cultivar is considered. The basic reproduction number corresponding to the non-autonomous system is derived and numerically computed to determine disease dynamics. Results showed that the disease dies out whenever the periodic basic reproduction number is less than unity and a periodic solution is obtained when it is greater than one. Results further showed that for both cultivars, the basic reproduction number increases with increasing values of the transmission rates and declines exponentially with increasing values of roguing rates. The critical roguing rate of ABB-genome cultivar was higher than that of AAA-genome cultivars. The peaks in disease prevalence indicate the importance of effective implementation of controls during the rainy season. We conclude that highly susceptible cultivars play an important role in the spread of BXW and control measures should be effectively implemented during the rainy season if BXW is to be eradicated.


Sign in / Sign up

Export Citation Format

Share Document