The aim of this work is to develop an effective coaxial personalized ventilator nozzle as add-on to ceiling diffuser to localize the air conditioning and fresh air needs of occupants in a space. The ceiling diffusers supply the space with circulated conditioned return air while the personalized coaxial ventilators supply fresh air directly to the breathing zone of occupants. The coaxial nozzle minimizes air entrainment between the fresh air stream and the space contaminated air and allows the effective delivery of fresh air from a substantial distance with lower amounts than what is required by ASHRAE standards. A detailed 3D CFD model was developed and used to optimize the nozzles dimensions and outlet flow characteristics. The CFD model numerical findings were then validated against experimental data where flow field measurements involving the flow rate and air quality were taken. The proposed air delivery system (coaxial personalized ventilator and angled ceiling diffuser) has substantially reduced air conditioning system energy consumption (up to 28%) when it was compared with conventional overhead mixing systems. Meanwhile, it permitted to obtain equivalent thermal comfort conditions and achieve higher breathing air quality (45% ventilation effectiveness at 10 L/s.person fresh air flow rate) compared to conventional mixed air systems with the privilege of the occupant being able to control his own microclimate.