Evaluation of the mechanisms involved in leucine-induced oxidative damage in cerebral cortex of young rats

2005 ◽  
Vol 39 (1) ◽  
pp. 71-79 ◽  
Author(s):  
Raquel Bridi ◽  
Alexandra Latini ◽  
César A. Braum ◽  
Giovanni K. Zorzi ◽  
Moacir Wajner ◽  
...  
Keyword(s):  
Cerebral Cortex ◽  
Oxidative Damage ◽  
Young Rats

Acute administration of 5-oxoproline induces oxidative damage to lipids and proteins and impairs antioxidant defenses in cerebral cortex and cerebellum of young rats

2010 ◽  
Vol 25 (2) ◽  
pp. 145-154 ◽  
Author(s):  
Carolina Didonet Pederzolli ◽  
Caroline Paula Mescka ◽  
Bernardo Remuzzi Zandoná ◽  
Daniella de Moura Coelho ◽  
Ângela Malysz Sgaravatti ◽  
...  
Keyword(s):  
Cerebral Cortex ◽  
Oxidative Damage ◽  
Antioxidant Defenses ◽  
Acute Administration ◽  
Young Rats

Neurochemical Evidence that the Metabolites Accumulating in 3-Methylcrotonyl-CoA Carboxylase Deficiency Induce Oxidative Damage in Cerebral Cortex of Young Rats

2012 ◽  
Vol 33 (1) ◽  
pp. 137-146 ◽  
Author(s):  
Ângela Zanatta ◽  
Alana Pimentel Moura ◽  
Anelise Miotti Tonin ◽  
Lisiane Aurélio Knebel ◽  
Mateus Grings ◽  
...  
Keyword(s):  
Cerebral Cortex ◽  
Oxidative Damage ◽  
Young Rats

scholarly journals Selenium Compounds Prevent the Effects of Methylmercury on the in Vitro Phosphorylation of Cytoskeletal Proteins in Cerebral Cortex of Young Rats

2005 ◽  
Vol 85 (1) ◽  
pp. 639-646 ◽  
Author(s):  
M. B. Moretto ◽  
C. Funchal ◽  
G. Zeni ◽  
R. Pessoa-Pureur ◽  
J. B. T. Rocha
Keyword(s):  
Cerebral Cortex ◽  
Cytoskeletal Proteins ◽  
Selenium Compounds ◽  
Young Rats

Effect of 950 MHz UHF electromagnetic radiation on biomarkers of oxidative damage, metabolism of UFA and antioxidants in the livers of young rats of different ages

2013 ◽  
Vol 90 (2) ◽  
pp. 159-168 ◽  
Author(s):  
Orlando V. Furtado-Filho ◽  
Juliana B. Borba ◽  
Alexsandro Dallegrave ◽  
Tânia M. Pizzolato ◽  
João A. P. Henriques ◽  
...  
Keyword(s):  
Oxidative Damage ◽  
Electromagnetic Radiation ◽  
Young Rats ◽  
Different Ages

Pristanic Acid Provokes Lipid, Protein, and DNA Oxidative Damage and Reduces the Antioxidant Defenses in Cerebellum of Young Rats

2014 ◽  
Vol 13 (6) ◽  
pp. 751-759 ◽  
Author(s):  
Estela Natacha Brandt Busanello ◽  
Vannessa Gonçalves Araujo Lobato ◽  
Ângela Zanatta ◽  
Clarissa Günther Borges ◽  
Anelise Miotti Tonin ◽  
...  
Keyword(s):  
Oxidative Damage ◽  
Antioxidant Defenses ◽  
Pristanic Acid ◽  
Dna Oxidative Damage ◽  
Young Rats

Aflatoxin B1 reduces non-enzymatic antioxidant defenses and increases protein kinase C activation in the cerebral cortex of young rats

2017 ◽  
Vol 21 (4) ◽  
pp. 268-275 ◽  
Author(s):  
Naiéli Schiefelbein Souto ◽  
Ana Claudia Monteiro Braga ◽  
Mayara Lutchemeyer de Freitas ◽  
Michele Rechia Fighera ◽  
Luiz Fernando Freire Royes ◽  
...  
Keyword(s):  
Cerebral Cortex ◽  
Protein Kinase C ◽  
Protein Kinase ◽  
Aflatoxin B1 ◽  
Antioxidant Defenses ◽  
Enzymatic Antioxidant ◽  
Young Rats ◽  
Kinase C ◽  
Protein Kinase C Activation

scholarly journals High Protein Diet Induces Oxidative Stress in Rat Cerebral Cortex and Hypothalamus

2019 ◽  
Vol 20 (7) ◽  
pp. 1547 ◽  
Author(s):  
Ewa Żebrowska ◽  
Mateusz Maciejczyk ◽  
Małgorzata Żendzian-Piotrowska ◽  
Anna Zalewska ◽  
Adrian Chabowski
Keyword(s):  
Oxidative Stress ◽  
Cerebral Cortex ◽  
Oxidative Damage ◽  
Antioxidant Defense ◽  
High Protein Diet ◽  
Brain Structures ◽  
High Protein ◽  
Protein Diet ◽  
Standard Diet ◽  
The Impact

This is the first study to analyze the impact of high protein diet (HPD) on antioxidant defense, redox status, as well as oxidative damage on both a local and systemic level. Male Wistar rats were divided into two equal groups (n = 9): HPD (44% protein) and standard diet (CON; 24.2% protein). After eight weeks, glutathione peroxidase (GPx), glutathione reductase (GR), catalase (CAT), superoxide dismutase-1 (SOD-1), reduced glutathione (GSH), uric acid (UA), total antioxidant (TAC)/oxidant status (TOS) as well as advanced glycation end products (AGE), 4-hydroxynonenal (4-HNE), and malondialdehyde (MDA) were analyzed in the serum/plasma, cerebral cortex, and hypothalamus of HPD and CON rats. HPD resulted in higher UA concentration and activity of GPx and CAT in the hypothalamus, whereas in the cerebral cortex these parameters remained unchanged. A significantly lower GSH content was demonstrated in the plasma and hypothalamus of HPD rats when compared to CON rats. Both brain structures expressed higher content of 4-HNE and MDA, whereas AGE was increased only in the hypothalamus of HPD animals. Despite the enhancement in antioxidant defense in the hypothalamus, this mechanism does not protect the hypothalamus from oxidative damage in rats. Hypothalamus is more susceptible to oxidative stress caused by HPD.

Tyrosine promotes oxidative stress in cerebral cortex of young rats

2008 ◽  
Vol 26 (6) ◽  
pp. 551-559 ◽  
Author(s):  
Ângela M. Sgaravatti ◽  
Bethânia A. Vargas ◽  
Bernardo R. Zandoná ◽  
Kátia B. Deckmann ◽  
Francieli J. Rockenbach ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Cerebral Cortex ◽  
Young Rats
Sign in / Sign up

Export Citation Format

Share Document