scholarly journals Overlap of obsessive–compulsive personality disorder and autism spectrum disorder traits among OCD outpatients: an exploratory study

2019 ◽  
Vol 23 (4) ◽  
pp. 297-306 ◽  
Author(s):  
W. Gadelkarim ◽  
S. Shahper ◽  
J. Reid ◽  
M. Wikramanayake ◽  
S. Kaur ◽  
...  
Keyword(s):  
Autism Spectrum Disorder ◽  
Personality Disorder ◽  
Exploratory Study ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Obsessive Compulsive ◽  
Obsessive Compulsive Personality Disorder

Obsessive compulsive Personality Disorder and Autism Spectrum Disorder Traits in the Obsessive-compulsive Disorder Clinic

2017 ◽  
Vol 41 (S1) ◽  
pp. S135-S136 ◽  
Author(s):  
W. Gadelkarim ◽  
S. Shahper ◽  
J. Reid ◽  
M. Wikramanayake ◽  
S. Kaur ◽  
...  
Keyword(s):  
Autism Spectrum Disorder ◽  
Personality Disorder ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
World Health ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Spectrum Disorders ◽  
Obsessive Compulsive Personality Disorder ◽  
The Impact

IntroductionObsessive Compulsive Personality Disorder (OCPD) is a common, highly co-morbid disorder. Subjected to comparatively little research, OCPD shares aspects of phenomenology and neuropsychology with obsessive-compulsive spectrum disorders and neurodevelopmental disorders such as autism spectrum disorder (ASD). A greater understanding of this interrelationship would provide new insights into its diagnostic classification and generate new research and treatment heuristics.AimsTo investigate the distribution of OCPD traits within a cohort of OCD patients. To evaluate the clinical overlap between traits of OCPD, OCD and ASD, as well as level of insight and treatment resistance.MethodWe interviewed 73 consenting patients from a treatment seeking OCD Specialist Service. We evaluated the severity of OCPD traits (Compulsive Personality Assessment Scale; CPAS), OCD symptoms (Yale–Brown Obsessive Compulsive Scale; Y-BOCS), ASD traits (Adult Autism Spectrum Quotient; AQ) and insight (Brown Assessment of Beliefs Scale; BABS).ResultsOut of 67 patients, 24 (36%) met DSM-IV criteria for OCPD, defined using the CPAS. Using Pearson's test, CPAS scores significantly (P < 0.01) correlated with total AQ and selected AQ domains but not with BABS. Borderline significant correlation was observed with Y-BOCS (P = 0.07). OCPD was not over-represented in a highly resistant OCD subgroup.ConclusionDisabling OCPD traits are common in the OCD clinic. They strongly associate with ASD traits, less strongly with OCD severity and do not appear related to poor insight or highly treatment-resistant OCD. The impact of OCPD on OCD treatment outcomes requires further research.Disclosure of interestThis work did not receive funding from external sources. Over the past few years, Dr. Fineberg has received financial support in various forms from the following: Shire, Otsuka, Lundbeck, Glaxo-SmithKline, Servier, Cephalon, Astra Zeneca, Jazz pharmaceuticals, Bristol Myers Squibb, Novartis, Medical Research Council (UK), National Institute for Health Research (UK), Wellcome Foundation, European College of Neuropsychopharmacology, UK College of Mental Health Pharmacists, British Association for Psychopharmacology, International College of Obsessive-Compulsive Spectrum Disorders, International Society for Behavioural Addiction, World Health Organization, Royal College of Psychiatrists.

Assessing gender differences in autism spectrum disorder using the Gendered Autism Behavioral Scale (GABS): An exploratory study

2021 ◽  
Vol 88 ◽  
pp. 101844
Author(s):  
Elaine Clarke ◽  
Laura Hull ◽  
Rachel Loomes ◽  
Carolyn E.B. McCormick ◽  
Stephen J. Sheinkopf ◽  
...  
Keyword(s):  
Gender Differences ◽  
Autism Spectrum Disorder ◽  
Exploratory Study ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Behavioral Scale

Evaluation of neuromuscular tone phenotypes in children with autism spectrum disorder: An exploratory study

2017 ◽  
Vol 47 (4) ◽  
pp. 261-268 ◽  
Author(s):  
Aude Paquet ◽  
Bertrand Olliac ◽  
Bernard Golse ◽  
Laurence Vaivre-Douret
Keyword(s):  
Autism Spectrum Disorder ◽  
Exploratory Study ◽  
Children With Autism ◽  
Autism Spectrum ◽  
Spectrum Disorder

scholarly journals An audit into the use of psychotropic medications in patients with autism spectrum disorder in a high security psychiatric hospital

BJPsych Open ◽  
2021 ◽  
Vol 7 (S1) ◽  
pp. S68-S68
Author(s):  
Elliott Carthy ◽  
David Murphy
Keyword(s):  
Autism Spectrum Disorder ◽  
Personality Disorder ◽  
Psychiatric Hospital ◽  
Autism Spectrum ◽  
Psychotropic Medications ◽  
Spectrum Disorder ◽  
Psychotic Symptoms ◽  
High Security ◽  
Psychotropic Medicines ◽  
Appropriate Prescribing

AimsAutism Spectrum Disorder (ASD) is a common neurodevelopmental disorder associated with difficulties in social communication and language development, preoccupations, a need for routine, sensory sensitivities and emotional dysregulation. People with autism who have violently offended may be prescribed psychotropic medications to treat comorbidities, or off-license to manage aggressive or challenging behaviours. However, the evidence base for their use remains scarce.MethodThis was a retrospective audit at Broadmoor Hospital, a high security psychiatric hospital in the United Kingdom, into the safe and appropriate prescribing of psychotropic medicines in those with an ASD compared to guidance from the National Institute for Health and Care Excellence (CG142): “Autism spectrum disorder in adults: diagnosis and management”. This first cycle was undertaken during May and June 2020 and included all patients with a confirmed or equivocal diagnosis of ASD in the preceding five years.ResultA total of 22 participants were included in this study. Of these, 17 participants had a confirmed diagnosis of ASD and five participants had a suspected diagnosis of ASD, but without formal confirmation with neurocognitive testing. A total of 13 (76.5%) participants with confirmed ASD were prescribed antipsychotic medication, nine of whom had an established comorbid mental disorder with psychotic symptoms. Of the remaining four, three had a diagnosis of a personality disorder. Three participants in this study had a confirmed diagnosis of ASD without any additional comorbid mental health diagnoses. No patients were prescribed psychotropic medicines for the core symptoms of ASD. The specific documentation of off-license use of antipsychotic medicines in those without a diagnosis of a psychotic disorder was poor. This was not recorded in any such participant in the preceding 12 months.ConclusionThis audit highlighted that dual diagnoses of ASD alongside non-affective psychosis and personality disorder are over-represented in this high security setting. The NICE clinical guidelines CG142 guidelines state that “antipsychotic medications should only be used for behaviour that challenges if …. the risk to the person or others is very severe”. By definition, all patients admitted to high security are deemed to be a grave and imminent risk to the public. Psychotropic medicines may therefore be clinically indicated at a much earlier stage than in community patients, instigated alongside appropriate psychosocial interventions and treatment of comorbid conditions. It may be that catered guidelines need to be formulated to support the safe and appropriate prescribing of psychotropic medicine in forensic settings.

scholarly journals Association Between Transient Hypothyroxinaemia of Prematurity and Adult Autism Spectrum Disorder in a Low-Birthweight Cohort: An Exploratory Study

2013 ◽  
Vol 27 (2) ◽  
pp. 182-187 ◽  
Author(s):  
Steven J. Korzeniewski ◽  
Jennifer A. Pinto-Martin ◽  
Agnes H. Whitaker ◽  
Judith F. Feldman ◽  
John M. Lorenz ◽  
...  
Keyword(s):  
Autism Spectrum Disorder ◽  
Exploratory Study ◽  
Low Birthweight ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Adult Autism

scholarly journals An Exploratory Study of Imagining Sounds and “Hearing” Music in Autism

2019 ◽  
Vol 50 (4) ◽  
pp. 1123-1132 ◽  
Author(s):  
Alex Bacon ◽  
C. Philip Beaman ◽  
Fang Liu
Keyword(s):  
Autism Spectrum Disorder ◽  
Exploratory Study ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Auditory Imagery ◽  
Typically Developing ◽  
And Control ◽  
Adults With Asd

AbstractIndividuals with autism spectrum disorder (ASD) reportedly possess preserved or superior music-processing skills compared to their typically developing counterparts. We examined auditory imagery and earworms (tunes that get “stuck” in the head) in adults with ASD and controls. Both groups completed a short earworm questionnaire together with the Bucknell Auditory Imagery Scale. Results showed poorer auditory imagery in the ASD group for all types of auditory imagery. However, the ASD group did not report fewer earworms than matched controls. These data suggest a possible basis in poor auditory imagery for poor prosody in ASD, but also highlight a separability between auditory imagery and control of musical memories. The separability is present in the ASD group but not in typically developing individuals.

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