scholarly journals The rise of the biocyborg: synthetic biology, artificial chimerism and human enhancement

2021 ◽  
pp. 1-21
Author(s):  
Léo Pio-Lopez
2020 ◽  
Author(s):  
Léo Pio-Lopez

Synthetic biology and gene editing opens new possibilities for human enhancement requiring ethical, societal and biopolitical considerations to evaluate its implications on the biopower and the human species. In this article, from a critical and exploratory analysis, we advocate that recent biotechnological developments allowed by synthetic biology (including gene editing) are transforming the line of forces of biopower and biopolitics. After having described the paradigm of life as an engineering discipline conveyed by synthetic biology, we first analyze using the concept of somatechnology that this technoscience is transforming the figure of the cyborg towards the biocyborg blurring the distinctions natural/artificial and man/machine. In second, we investigate the bioeconomy of enhancement and its effect on how the individuals developed new modes of subjectivation and how they consider their own bodies. We end the article by analysing the transformations of biopower with gene editing and the use of technologies of genetic self-modification by self-experimenters.


Planta Medica ◽  
2013 ◽  
Vol 79 (13) ◽  
Author(s):  
A Sarrion-Perdigones ◽  
M Vazquez-Vilar ◽  
J Palaci ◽  
A Granell ◽  
D Orzáez

Somatechnics ◽  
2012 ◽  
Vol 2 (2) ◽  
pp. 250-262 ◽  
Author(s):  
Oron Catts ◽  
Ionat Zurr

The paper discusses and critiques the concept of the single engineering paradigm. This concepts allude to a future in which the control of matter and life, and life as matter, will be achieved by applying engineering principles; through nanotechnology, synthetic biology and, as some suggest, geo-engineering, cognitive engineering and neuro-engineering. We outline some issues in the short history of the field labelled as Synthetic Biology. Furthermore; we examine the way engineers, scientists, designers and artists are positioned and articulating the use of the tools of Synthetic Biology to expose some of the philosophical, ethical and political forces and considerations of today as well as some future scenarios. We suggest that one way to enable the possibilities of alternative frames of thought is to open up the know-how and the access to these technologies to other disciplines, including artistic.


2016 ◽  
Vol 23 (2) ◽  
pp. 159-174
Author(s):  
William Daley
Keyword(s):  

2018 ◽  
Vol 27 (3) ◽  
pp. i-vii
Author(s):  
Luisa Damiano ◽  
◽  
Yutetsu Kuruma ◽  
Pasquale Stano ◽  
◽  
...  

2019 ◽  
Author(s):  
Thomas Siemon ◽  
Zhangqian Wang ◽  
Guangkai Bian ◽  
Tobias Seitz ◽  
Ziling Ye ◽  
...  

Herein, we report the semisynthetic production of the potent transient receptor potential canonical (TRPC) channel agonist (−)-englerin A (EA), using guaia-6,10(14)-diene as the starting material. Guaia-6,10(14)-diene was systematically engineered in Escherichia coli and Saccharomyces cerevisiae using the CRISPR/Cas9 system and produced with high titers. This provided us the opportunity to execute a concise chemical synthesis of EA and the two related guaianes (−)-oxyphyllol and (+)-orientalol E. The potentially scalable approach combines the advantages of synthetic biology and chemical synthesis and provides an efficient and economical method for producing EA as well as its analogs.


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