CA125 suppresses amatuximab immune-effector function and elevated serum levels are associated with reduced clinical response in first line mesothelioma patients

Nicholas C. Nicolaides; Charles Schweizer; Elizabeth B. Somers; Wenquan Wang; Shawn Fernando; Erin N. Ross; Luigi Grasso; Raffit Hassan; J. Bradford Kline

doi:10.1080/15384047.2018.1449614

CA125 suppresses amatuximab immune-effector function and elevated serum levels are associated with reduced clinical response in first line mesothelioma patients

Cancer Biology & Therapy ◽

10.1080/15384047.2018.1449614 ◽

2018 ◽

Vol 19 (7) ◽

pp. 622-630 ◽

Cited By ~ 2

Author(s):

Nicholas C. Nicolaides ◽

Charles Schweizer ◽

Elizabeth B. Somers ◽

Wenquan Wang ◽

Shawn Fernando ◽

...

Keyword(s):

Clinical Response ◽

Elevated Serum ◽

Serum Levels ◽

Effector Function ◽

First Line ◽

Immune Effector ◽

Immune Effector Function

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A Novel Therapeutic Strategy to Rescue the Immune Effector Function of Proteolytically Inactivated Cancer Therapeutic Antibodies

Molecular Cancer Therapeutics ◽

10.1158/1535-7163.mct-14-0715 ◽

2014 ◽

Vol 14 (3) ◽

pp. 681-691 ◽

Cited By ~ 12

Author(s):

Xuejun Fan ◽

Randall J. Brezski ◽

Hui Deng ◽

Pooja M. Dhupkar ◽

Yun Shi ◽

...

Keyword(s):

Therapeutic Strategy ◽

Effector Function ◽

Therapeutic Antibodies ◽

Immune Effector ◽

Immune Effector Function ◽

Novel Therapeutic

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Impact of iron treatment on immune effector function and cellular iron status of circulating monocytes in dialysis patients

Nephrology Dialysis Transplantation ◽

10.1093/ndt/gfq483 ◽

2010 ◽

Vol 26 (3) ◽

pp. 977-987 ◽

Cited By ~ 31

Author(s):

T. Sonnweber ◽

I. Theurl ◽

M. Seifert ◽

A. Schroll ◽

S. Eder ◽

...

Keyword(s):

Iron Status ◽

Effector Function ◽

Dialysis Patients ◽

Immune Effector ◽

Cellular Iron ◽

Iron Treatment ◽

Immune Effector Function

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The PI3Kδ-Selective Inhibitor Idelalisib Minimally Interferes with Immune Effector Function Mediated by Rituximab or Obinutuzumab and Significantly Augments B Cell Depletion In Vivo

The Journal of Immunology ◽

10.4049/jimmunol.1700323 ◽

2018 ◽

Vol 200 (7) ◽

pp. 2304-2312 ◽

Cited By ~ 8

Author(s):

Adam Palazzo ◽

Sylvia Herter ◽

Laura Grosmaire ◽

Randy Jones ◽

Christian R. Frey ◽

...

Keyword(s):

B Cell ◽

Selective Inhibitor ◽

Effector Function ◽

Cell Depletion ◽

B Cell Depletion ◽

Immune Effector ◽

Immune Effector Function

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Abstract LB-218: Protein arginine methyltransferase inhibition of malignant gliomas leads to restored chemokine expression and enhanced immune effector function

10.1158/1538-7445.am2015-lb-218 ◽

2015 ◽

Author(s):

Fengting Yan ◽

Yeshavanth Banasavadi-Siddegowda ◽

John T. Patton ◽

Mark Lustberg ◽

Xin Wu ◽

...

Keyword(s):

Malignant Gliomas ◽

Effector Function ◽

Protein Arginine Methyltransferase ◽

Arginine Methyltransferase ◽

Immune Effector ◽

Chemokine Expression ◽

Immune Effector Function

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Beta-2-microglobulin elevated serum levels highly correlate with tumor burden and clinical response in newly diagnosed and relapsed Non-Hodgkin's Lymphomas treated with standard doses chemotherapy

European Journal of Cancer ◽

10.1016/s0959-8049(99)81789-4 ◽

1999 ◽

Vol 35 ◽

pp. S340

Author(s):

R. Bordonaro ◽

F. Ferrau ◽

D. Gluffrida ◽

M. Ursino ◽

D. Priolo ◽

...

Keyword(s):

Clinical Response ◽

Elevated Serum ◽

Serum Levels ◽

Tumor Burden ◽

Newly Diagnosed ◽

Beta 2 ◽

Beta 2 Microglobulin ◽

Hodgkin's Lymphomas

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The sequestration hypothesis: an explanation for the sensitivity of malaria parasites to nitric oxide-mediated immune effector function in vivo

Medical Hypotheses ◽

10.1054/mehy.1999.0914 ◽

2000 ◽

Vol 54 (4) ◽

pp. 638-641 ◽

Cited By ~ 9

Author(s):

A.W. Taylor-Robinson

Keyword(s):

Nitric Oxide ◽

Effector Function ◽

Malaria Parasites ◽

Immune Effector ◽

Immune Effector Function

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Avidity confers FcγR binding and immune effector function to aglycosylated immunoglobulin G1

Journal of Molecular Recognition ◽

10.1002/jmr.2155 ◽

2012 ◽

Vol 25 (3) ◽

pp. 147-154 ◽

Cited By ~ 38

Author(s):

Thomas C. Nesspor ◽

T. Shantha Raju ◽

Chen -Ni Chin ◽

Omid Vafa ◽

Randall J. Brezski

Keyword(s):

Effector Function ◽

Immune Effector ◽

Immune Effector Function

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“Structural imprinting” of the cutaneous immune effector function

Tissue Barriers ◽

10.1080/21688370.2020.1851561 ◽

2020 ◽

pp. 1851561

Author(s):

Yosuke Ishitsuka ◽

Dennis R. Roop ◽

Tatsuya Ogawa

Keyword(s):

Effector Function ◽

Immune Effector ◽

Immune Effector Function

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Lenalidomide-based maintenance therapy reduces TNF receptor 2 on CD4 T cells and enhances immune effector function in acute myeloid leukemia patients

American Journal of Hematology ◽

10.1002/ajh.23746 ◽

2014 ◽

Vol 89 (8) ◽

pp. 795-802 ◽

Cited By ~ 23

Author(s):

Chindu Govindaraj ◽

Mutsa Madondo ◽

Ying Ying Kong ◽

Peter Tan ◽

Andrew Wei ◽

...

Keyword(s):

T Cells ◽

Acute Myeloid Leukemia ◽

Maintenance Therapy ◽

Cd4 T Cells ◽

Myeloid Leukemia ◽

Effector Function ◽

Tnf Receptor ◽

Immune Effector ◽

Immune Effector Function ◽

Acute Myeloid

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Short-hairpin-RNA-mediated silencing of fucosyltransferase 8 in Chinese-hamster ovary cells for the production of antibodies with enhanced antibody immune effector function

Biotechnology and Applied Biochemistry ◽

10.1042/ba20080220 ◽

2009 ◽

Vol 53 (1) ◽

pp. 31 ◽

Cited By ~ 14

Author(s):

Vincent Beuger ◽

Klaus-Peter Künkele ◽

Hans Koll ◽

Achim Gärtner ◽

Monika Bähner ◽

...

Keyword(s):

Chinese Hamster Ovary ◽

Chinese Hamster Ovary Cells ◽

Chinese Hamster ◽

Short Hairpin Rna ◽

Effector Function ◽

Hairpin Rna ◽

Ovary Cells ◽

Immune Effector ◽

Short Hairpin ◽

Immune Effector Function

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