LncRNA HOXD-AS1 affects proliferation and apoptosis of cervical cancer cells by promoting FRRS1 expression via transcription factor ELF1

Cell Cycle ◽  
2022 ◽  
pp. 1-11
Author(s):  
Huan Liu ◽  
Li Liu ◽  
Qiong Liu ◽  
Fengjiao He ◽  
Hong Zhu
Keyword(s):  
Cervical Cancer ◽  
Transcription Factor ◽  
Cancer Cells ◽  
Proliferation And Apoptosis ◽  
Cervical Cancer Cells

scholarly journals The Brn-3a transcription factor plays a key role in regulating the growth of cervical cancer cells in vivo

Oncogene ◽  
2001 ◽  
Vol 20 (35) ◽  
pp. 4899-4903 ◽  
Author(s):  
Daniel Ndisang ◽  
Vishwanie Budhram-Mahadeo ◽  
Barbara Pedley ◽  
David S Latchman
Keyword(s):  
Cervical Cancer ◽  
Transcription Factor ◽  
Cancer Cells ◽  
Cervical Cancer Cells

scholarly journals Cytotoxic Effects of Native and Recombinant Frutalin, a Plant Galactose-Binding Lectin, on HeLa Cervical Cancer Cells

2011 ◽  
Vol 2011 ◽  
pp. 1-9 ◽  
Author(s):  
Carla Oliveira ◽  
Ana Nicolau ◽  
José A. Teixeira ◽  
Lucília Domingues
Keyword(s):  
Cervical Cancer ◽  
Cancer Cells ◽  
Hela Cells ◽  
Carbohydrate Binding ◽  
Binding Affinities ◽  
Proliferation And Apoptosis ◽  
Cervical Cancer Cells ◽  
Different Sources ◽  
Binding Lectin ◽  
Galactose Binding Lectin

Frutalin is theα-D-galactose-binding lectin isolated from breadfruit seeds. Frutalin was obtained from two different sources: native frutalin was purified from its natural origin, and recombinant frutalin was produced and purified fromPichia pastoris. This work aimed to study and compare the effect of native and recombinant frutalin on HeLa cervical cancer cells proliferation and apoptosis. Furthermore, the interaction between frutalin and the HeLa cells was investigated by confocal microscopy. Despite having different carbohydrate-binding affinities, native and recombinant frutalin showed an identical magnitude of cytotoxicity on HeLa cells growth (IC50~100 μg/mL) and equally induced cell apoptosis. The interaction studies showed that both lectins were rapidly internalised and targeted to HeLa cell's nucleus. Altogether, these results indicate that frutalin action is not dependent on its sugar-binding properties. This study provides important information about the bioactivity of frutalin and contributes to the understanding of the plant lectins cytotoxic activity.

scholarly journals Expression of TSG101 protein and LSF transcription factor in HPV-positive cervical cancer cells

2014 ◽  
Vol 7 (5) ◽  
pp. 1409-1413 ◽  
Author(s):  
JUSTYNA K. BRONIARCZYK ◽  
ALICJA WAROWICKA ◽  
ANNA KWAŚNIEWSKA ◽  
MARIA WOHUŃ-CHOLEWA ◽  
WOJCIECH KWAŚNIEWSKI ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Transcription Factor ◽  
Cancer Cells ◽  
Cervical Cancer Cells

The effects of lanthanum chloride on proliferation and apoptosis of cervical cancer cells: involvement of let-7a and miR-34a microRNAs

BioMetals ◽  
2015 ◽  
Vol 28 (5) ◽  
pp. 879-890 ◽  
Author(s):  
Lingfang Yu ◽  
Jieqi Xiong ◽  
Ling Guo ◽  
Lifang Miao ◽  
Sisun Liu ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cancer Cells ◽  
Lanthanum Chloride ◽  
Proliferation And Apoptosis ◽  
Cervical Cancer Cells
Sign in / Sign up

Export Citation Format

Share Document