Synthesis, Characterization, and In Vitro Bioactivity of Sol-Gel-Derived SiO2–CaO–P2O5–MgO-SrO Bioactive Glass

The paper reports the first attempt at changing cooling treatment of synthesizing method in order to investigate its effect on the physical properties of sol-gel derived nano bioactive glass-ceramic in the system 58SiO2-33CaO-9P2O5 (wt.%). We hypothesized that the method of cooling may affect the properties of nano bioactive glass-ceramic. To test this hypothesis, two different method of cooling treatment was applied after calcinations in synthesizing method. Both quenched and unquenched nano bioactive glass-ceramics were soaked in Ringer?s solution with bovine serum albumin (BSA) for bioactivity evaluation. The obtained samples were analyzed for their composition, crystalinity and morphology through X-ray powder diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), surface electron microscope (SEM) and transmission electron microscope (TEM). The SEM images showed that the morphology of nano bioactive glass-ceramics was completely changed by quenching process. Results of in vitro bioactivity evaluation revealed that the unquenched attains faster apatite formation ability than the quenched sample. Other properties of these two morphologically different nano bioactive glass-ceramics were strongly discussed.

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The 1100 C Thermoluminescence Peak as a Probe in Bioactivity Study of the 58S Sol-Gel Bioactive Glass

Key Engineering Materials ◽

10.4028/www.scientific.net/kem.493-494.49 ◽

2011 ◽

Vol 493-494 ◽

pp. 49-54 ◽

Cited By ~ 1

Author(s):

George S. Polymeris ◽

Ourania Menti Goudouri ◽

Konstantinos M. Paraskevopoulos ◽

George Kitis

Keyword(s):

Bioactive Glass ◽

Time Scale ◽

Immersion Time ◽

Sol Gel ◽

Glow Peak ◽

In Vitro Bioactivity ◽

Effective Application ◽

Peak Intensity ◽

Sbf Solution

Results of the present study provide strong indications towards the effective application of the 110oC Thermoluminescence (TL) peak in discriminating between different bioactive responses for the case of the 58S bioactive glass. The in vitro bioactivity of this glass in the form of powder in SBF solution was tested for various immersion times, ranging between 0 and 6 days. This TL peak is ubiquitously present in all 58S samples, for all immersion times. The intensity of the110oC TL peak was proven to be very sensitive to the different bioactive responses, indicating a strongly decreasing pattern with increasing immersion time in SBF, easily identifying thus the loss of silica. This loss is reflected to the decrease of the 110oC TL peak intensity, which appears to be fast even for the shorter immersion times. The 110oC TL glow peak intensity and sensitization could also be yielding a time scale regarding the beginning of some among the several stages included in the bioactivity sequence.

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Characterization, in vitro bioactivity and biological studies of sol-gel synthesized SrO substituted 58S bioactive glass

Ceramics International ◽

10.1016/j.ceramint.2017.08.004 ◽

2017 ◽

Vol 43 (17) ◽

pp. 14880-14890 ◽

Cited By ~ 25

Author(s):

Amirhossein Moghanian ◽

Sadegh Firoozi ◽

Mohammadreza Tahriri

Keyword(s):

Bioactive Glass ◽

Sol Gel ◽

In Vitro Bioactivity ◽

Biological Studies

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In Vitro Bioactivity Studies of Sol-Gel Derived Dental Ceramics/Bioactive Glass Composites in Periodically Renewed Biomimetic Solution

Bioceramics Development and Applications ◽

10.4303/bda/d110250 ◽

2011 ◽

Vol 1 ◽

pp. 1-4 ◽

Cited By ~ 4

Author(s):

O. M. Goudouri ◽

E. Kontonasaki ◽

A. Theocharidou ◽

L. Papadopoulou ◽

X. Chatzistavrou ◽

...

Keyword(s):

Bioactive Glass ◽

Sol Gel ◽

Dental Ceramics ◽

In Vitro Bioactivity ◽

Glass Composites

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Synthesis and Characterization of Silver–Strontium (Ag-Sr)-Doped Mesoporous Bioactive Glass Nanoparticles

Gels ◽

10.3390/gels7020034 ◽

2021 ◽

Vol 7 (2) ◽

pp. 34

Author(s):

Shaher Bano ◽

Memoona Akhtar ◽

Muhammad Yasir ◽

Muhammad Salman Maqbool ◽

Akbar Niaz ◽

...

Keyword(s):

Bioactive Glass ◽

Composite Coatings ◽

Antibacterial Properties ◽

Bone Diseases ◽

Osteogenic Potential ◽

Diffusion Method ◽

Charge Composition ◽

In Vitro Bioactivity ◽

Mesoporous Bioactive Glass

Biomedical implants are the need of this era due to the increase in number of accidents and follow-up surgeries. Different types of bone diseases such as osteoarthritis, osteomalacia, bone cancer, etc., are increasing globally. Mesoporous bioactive glass nanoparticles (MBGNs) are used in biomedical devices due to their osteointegration and bioactive properties. In this study, silver (Ag)- and strontium (Sr)-doped mesoporous bioactive glass nanoparticles (Ag-Sr MBGNs) were prepared by a modified Stöber process. In this method, Ag+ and Sr2+ were co-substituted in pure MBGNs to harvest the antibacterial properties of Ag ions, as well as pro-osteogenic potential of Sr2 ions. The effect of the two-ion concentration on morphology, surface charge, composition, antibacterial ability, and in-vitro bioactivity was studied. Scanning electron microscopy (SEM), X-Ray diffraction (XRD), and Fourier transform infrared spectroscopy (FTIR) confirmed the doping of Sr and Ag in MBGNs. SEM and EDX analysis confirmed the spherical morphology and typical composition of MBGNs, respectively. The Ag-Sr MBGNs showed a strong antibacterial effect against Staphylococcus carnosus and Escherichia coli bacteria determined via turbidity and disc diffusion method. Moreover, the synthesized Ag-Sr MBGNs develop apatite-like crystals upon immersion in simulated body fluid (SBF), which suggested that the addition of Sr improved in vitro bioactivity. The Ag-Sr MBGNs synthesized in this study can be used for the preparation of scaffolds or as a filler material in the composite coatings for bone tissue engineering.

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