scholarly journals Microbiota and mucosal defense in IBD: an update

2019 ◽  
Vol 13 (10) ◽  
pp. 963-976 ◽  
Author(s):  
Eduard F. Stange ◽  
Bjoern O. Schroeder
Keyword(s):  
Mucosal Defense

scholarly journals ZBP-89 Regulates Expression of Tryptophan Hydroxylase I and Mucosal Defense Against Salmonella Typhimurium in Mice

2013 ◽  
Vol 144 (7) ◽  
pp. 1466-1477.e9 ◽  
Author(s):  
Bryan E. Essien ◽  
Helmut Grasberger ◽  
Rachael D. Romain ◽  
David J. Law ◽  
Natalia A. Veniaminova ◽  
...  
Keyword(s):  
Salmonella Typhimurium ◽  
Tryptophan Hydroxylase ◽  
Mucosal Defense

scholarly journals Review : Role of mast cells in gastrointestinal mucosal defense

BIOCELL ◽  
2003 ◽  
Vol 27 (2) ◽  
pp. 163-172 ◽  
Author(s):  
Alicia B. Penissi ◽  
Mar韆 I. Rudolph ◽  
Ram髇 S. Piezzi
Keyword(s):  
Mast Cells ◽  
Mucosal Defense

Antiulcer Effects of Alpha Lipoic Acid on Gastric Acid Secretion and Mucosal Defense Factors in Rats

2011 ◽  
Vol 6 (6) ◽  
pp. 426-438 ◽  
Author(s):  
M.A. Abd El-Kader ◽  
M.M. Ali ◽  
N.M. El-Sammad ◽  
M.A. El-Shaer
Keyword(s):  
Acid Secretion ◽  
Gastric Acid Secretion ◽  
Gastric Acid ◽  
Lipoic Acid ◽  
Alpha Lipoic Acid ◽  
Mucosal Defense

scholarly journals Emerging roles for cyclooxygenase-2 in gastrointestinal mucosal defense

2005 ◽  
Vol 145 (3) ◽  
pp. 275-282 ◽  
Author(s):  
John L Wallace ◽  
Pallavi R Devchand
Keyword(s):  
Cyclooxygenase 2 ◽  
Mucosal Defense

W1210 FC Gamma Receptors On Antigen Presenting Cells Can Regulate the Mucosal Defense Against Enteric Bacteria

2008 ◽  
Vol 134 (4) ◽  
pp. A-655
Author(s):  
Atsuhiro Masuda ◽  
Masaru Yoshida ◽  
Tsukasa Ishida ◽  
Ryo Chinzei ◽  
Hiroshi Tanaka ◽  
...  
Keyword(s):  
Antigen Presenting Cells ◽  
Enteric Bacteria ◽  
Fc Gamma Receptors ◽  
Mucosal Defense ◽  
Antigen Presenting

Mucosal defense against enteric pathogens

1983 ◽  
Vol 50 (3) ◽  
pp. 311-317
Author(s):  
S. C. Sanyal
Keyword(s):  
Enteric Pathogens ◽  
Mucosal Defense

Cholecystokinin secretagogue-induced gastroprotection: role of nitric oxide and blood flow

2003 ◽  
Vol 284 (3) ◽  
pp. G399-G410 ◽  
Author(s):  
Sonlee D. West ◽  
Kenneth S. Helmer ◽  
Lily K. Chang ◽  
Yan Cui ◽  
George H. Greeley ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Blood Flow ◽  
Mucosal Blood Flow ◽  
Gastric Mucosal Blood Flow ◽  
Gastric Injury ◽  
Protective Mechanism ◽  
Adaptive Cytoprotection ◽  
Mucosal Defense ◽  
Calcium Dependent

This study was done to examine the role of CCK in gastric mucosal defense and to assess the gastroprotective roles of nitric oxide and blood flow. In rats, the CCK secretagogues oleate and soybean trypsin inhibitor augmented gastric mucosal blood flow and prevented gastric injury from luminal irritants. Type A CCK receptor blockade negated CCK secretagogue-induced gastroprotection and exacerbated gastric injury from bile and ethanol but did not block adaptive cytoprotection. CCK secretagogue-induced gastroprotection and hyperemia were negated by nonselective nitric oxide synthase (NOS) inhibition ( N G-nitro-l-arginine methyl ester) but not by selective inducible NOS inhibition (aminoguanidine). Gastric mucosal calcium-dependent NOS activity, but not calcium-independent NOS activity, was increased following CCK and CCK secretagogues. The release of endogenous CCK plays a role in the intrinsic gastric mucosal defense system against injury from luminal irritants. The protective mechanism appears to involve increased production of nitric oxide from primarily the constitutive isoforms of NOS and a resultant increase in blood flow.

Sign in / Sign up

Export Citation Format

Share Document