Multiple bone lesions in a patient with fatigue: case report of bone sarcoidosis

Abstract Background Although epithelioid hemangiomas involving bone have been described in previous case reports and case series, the effects of radiation therapy on vertebral epithelioid hemangioma has not been fully reported. Here we provide a case report of tumor response to radiation therapy in a young adult with a large epithelioid hemangioma involving the fourth lumbar vertebrae. Case presentation A 27-year-old Latino man with a past medical history of type 1 diabetes and a 3-year history of low back pain presented to a hospital emergency department following acute worsening of back pain. On transfer to our tertiary medical center, he described the pain as “shock-like” which originated at the lateral aspect of his right hip and radiated down to his right knee. Paresthesia was also reported along the medial aspect of his lower right leg. Imaging included a computed tomography scan and magnetic resonance imaging which revealed fourth lumbar and right iliac lytic bone lesions. Image-guided biopsies of the lytic lesions were consistent with a diagnosis of epithelioid hemangioma and radiation therapy was recommended as the primary treatment. Our patient’s low back and leg pain were initially managed with acetaminophen, oxycodone, pregabalin, and lidocaine patch 5%. He noted improvement in pain after his third fraction of radiation. Pain intensity continued to decline and oxycodone was discontinued. Conclusions This case report demonstrates an unusual etiology of back and leg pain in a young man and elucidates the palliative effects of radiation therapy for epithelioid hemangioma involving the lumbar spine.

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Aneurysmal Bone Cyst of the Skull Base—Case Report

Arquivos Brasileiros de Neurocirurgia Brazilian Neurosurgery ◽

10.1055/s-0036-1584508 ◽

2016 ◽

Vol 38 (01) ◽

pp. 051-055

Author(s):

Arnon Alves Filho ◽

Adans Porfírio ◽

Washington Ribeiro ◽

Daniel Fonseca ◽

Moana Malta ◽

...

Keyword(s):

Case Report ◽

Cavernous Sinus ◽

Aneurysmal Bone Cyst ◽

Bone Cyst ◽

Unknown Etiology ◽

Base Case ◽

Bone Lesions ◽

Histopathological Analysis ◽

Suprasellar Region ◽

Pubmed Database

Introduction Aneurysmal bone cysts (ABCs) are pseudotumoral bone lesions of unknown etiology that are also hypervascularized, benign, and locally destructive. They are rare in the base of the skull. The present case report describes a case of aneurysmal bone cyst in the sella turcica. Case Report The present study was developed at the department of neurosurgery of the Hospital Universitário Professor Alberto Antunes of the Universidade Federal de Alagoas (HUPAA-AL, in the Portuguese acronym), Maceió, state of Alagoas, Brazil, and is accompanied by a review of the literature from the PubMed database. A 17-year-old female patient with bitemporal hemianopia and intense left hemicranial headache associated with symptoms from the cranial nerves contained in the cavernous sinus. Neuroimaging evidenced a large lesion in the suprasellar region with calcification foci, sellar erosion, and extension to the cavernous sinus. The patient was submitted to a partial lesion resection and the histopathological analysis showed an aneurysmal bone cyst. Conclusion A rare case of intracranial aneurysmal bone cyst, with the important differential diagnosis from pituitary adenoma.

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PReS-FINAL-2237: The diagnostic challenge of osteolytic bone lesions in autoinflammatory diseases: a case report

Pediatric Rheumatology ◽

10.1186/1546-0096-11-s2-p227 ◽

2013 ◽

Vol 11 (S2) ◽

Author(s):

R Caorsi ◽

P Picco ◽

A Buoncompagni ◽

S Signa ◽

F Minoia ◽

...

Keyword(s):

Case Report ◽

Autoinflammatory Diseases ◽

Bone Lesions ◽

Diagnostic Challenge

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Multifocal osteonecrosis secondary to occupational exposure to aluminum

Acta Ortopédica Brasileira ◽

10.1590/1413-785220172503170760 ◽

2017 ◽

Vol 25 (3) ◽

pp. 103-106 ◽

Cited By ~ 3

Author(s):

Jorge Henrique Assunção ◽

Eduardo Angeli Malavolta ◽

Mauro Emilio Conforto Gracitelli ◽

Renée Zon Filippi ◽

Arnaldo Amado Ferreira Neto

Keyword(s):

Renal Failure ◽

Risk Factor ◽

Case Report ◽

Occupational Exposure ◽

Aluminum Toxicity ◽

Bone Lesions ◽

Main Risk Factor ◽

Level Of Evidence ◽

Aluminum Level ◽

Chronic Use

ABSTRACT Multifocal osteonecrosis is a rare disease; chronic use of corticosteroids is considered the main risk factor. Patients with chronic renal failure can develop aluminum toxicity, which can lead to osteomalacia and encephalopathy. An association between osteonecrosis and aluminum toxicity has been reported among patients with dialytic renal insufficiency. Occupational exposure to aluminum rarely causes lung disease and no cases of bone lesions resulting from exposure to this metal have been reported. In this manuscript, we describe a novel case of a patient with multifocal osteonecrosis associated with chronic occupational exposure to aluminum. Level of Evidence IV, Case Report.

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Brown Tumors: A Case Report and Review of the Literature

Case Reports in Nephrology and Dialysis ◽

10.1159/000444703 ◽

2016 ◽

Vol 6 (1) ◽

pp. 46-52 ◽

Cited By ~ 7

Author(s):

Özgür Can ◽

Başak Boynueğri ◽

Ali Murat Gökçe ◽

Ebru Özdemir ◽

Ferhat Ferhatoğlu ◽

...

Keyword(s):

Case Report ◽

Secondary Hyperparathyroidism ◽

English Literature ◽

Bone Lesions ◽

Brown Tumor ◽

Review Of The Literature ◽

Normal Functions ◽

Brown Tumors ◽

Clinically Significant

Brown tumors are focal bone lesions, encountered in patients with uncontrolled hyperparathyroidism. They can be located in any part of the skeleton. Clinically significant lesions in the craniofacial bones are rare. Craniofacial involvement may cause facial disfiguration and compromise social ease of the patient and normal functions, such as chewing, talking, and breathing. In this case report, we present a patient with a brown tumor of the craniofacial bones provoked by secondary hyperparathyroidism and review the last 10 years of craniofacial brown tumors associated with secondary hyperparathyroidism in the English literature.

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