scholarly journals A patient with a history of breast cancer and multiple bone lesions: a case report

2017 ◽  
Vol 11 (1) ◽  
Author(s):  
Marie-Angela Schnyder ◽  
Paul Stolzmann ◽  
Gerhard Frank Huber ◽  
Christoph Schmid
2019 ◽  
Vol 13 (1) ◽  
Author(s):  
Aldis P. Siltumens ◽  
Na L. Smith ◽  
Rosalind F. Sharain ◽  
Michael G. Haddock ◽  
W. Michael Hooten

Abstract Background Although epithelioid hemangiomas involving bone have been described in previous case reports and case series, the effects of radiation therapy on vertebral epithelioid hemangioma has not been fully reported. Here we provide a case report of tumor response to radiation therapy in a young adult with a large epithelioid hemangioma involving the fourth lumbar vertebrae. Case presentation A 27-year-old Latino man with a past medical history of type 1 diabetes and a 3-year history of low back pain presented to a hospital emergency department following acute worsening of back pain. On transfer to our tertiary medical center, he described the pain as “shock-like” which originated at the lateral aspect of his right hip and radiated down to his right knee. Paresthesia was also reported along the medial aspect of his lower right leg. Imaging included a computed tomography scan and magnetic resonance imaging which revealed fourth lumbar and right iliac lytic bone lesions. Image-guided biopsies of the lytic lesions were consistent with a diagnosis of epithelioid hemangioma and radiation therapy was recommended as the primary treatment. Our patient’s low back and leg pain were initially managed with acetaminophen, oxycodone, pregabalin, and lidocaine patch 5%. He noted improvement in pain after his third fraction of radiation. Pain intensity continued to decline and oxycodone was discontinued. Conclusions This case report demonstrates an unusual etiology of back and leg pain in a young man and elucidates the palliative effects of radiation therapy for epithelioid hemangioma involving the lumbar spine.


2011 ◽  
Vol 07 (02) ◽  
pp. 116
Author(s):  
Yogesh Gandhi ◽  
Sunil Gandhi ◽  
◽  

An accurate cancer diagnosis is critical as it can direct the use of site-directed, and potentially more effective, treatment options for specific types of cancer. A differential or uncertain diagnosis could prevent cancer patients from receiving optimal treatment, thus affecting their overall prognosis. Advances in molecular technology have led to the development of molecular cancer classifiers that can direct or confirm the diagnosis of metastatic cancers which would otherwise be considered uncertain or unknown. This case report describes the role of molecular diagnostics in the evaluation of a patient with a large pancreatic mass and a history of breast cancer. Results from a 92-gene molecular profiling assay (CancerTYPE ID®) predicted that this new mass was breast cancer. This diagnosis allowed for effective treatment and complete response in this patient.


Author(s):  
Pande Ayu Kirana Dewi ◽  
I. Nengah Raditha

Breast cancer is one of the most common malignancies. This malignancy can originate from the epithelium of the ducts or lobules of the breast. Although rare, breast cancer can also be found in men. The incidence of breast cancer in men is <1% of the total breast cancer and it is estimated that 1 in 100.00 men worldwide is diagnosed with breast cancer. Breast cancer in pediatric patients is rare. Incidence of breast cancer in pediatric is estimated to be 0.2-0.8/100.000 for females with less than 20 years old. In this case report is a 14-years-old male with ten years history of a mass in his right breast. At first the mass was said to be as small as a marble, then since last year the mass have grown bigger. Biopsy and histopathology examination were performed to confirm the diagnosis. The result of histopathology examination was ductal invasive carcinoma. The patient and family refused to undergo chemotherapy. The incidence of breast cancer in pediatric is rare, and it has high mortality rate in pediatric patient.


Hand ◽  
2007 ◽  
Vol 2 (3) ◽  
pp. 101-103 ◽  
Author(s):  
John B. Hijjawi ◽  
David G. Dennison

Breast cancer now affects 1 in 8 American women and the taxane agent paclitaxel (Taxol® Bristol-Myers Squibb) is a major tool in the treatment of many such patients. Hand surgeons are therefore likely to encounter upper extremity complications related to the use of taxane therapy. We present an unusual case of a felon developing in a breast cancer patient on paclitaxel therapy with no antecedent history of trauma. Whereas onycholysis and subungual hemorrhage are reported complications of taxane therapy ( Fig. 1 ), an acute felon with or without associated paronychia is an unusual and more aggressive manifestation of this drug-related nail dystrophy.


Cases Journal ◽  
2009 ◽  
Vol 2 (1) ◽  
Author(s):  
Chintamani ◽  
Rohan Khandelwal ◽  
Megha Tandon ◽  
K Yashwant ◽  
Pranjal Kulshreshtha ◽  
...  

2018 ◽  
Vol 2018 ◽  
pp. 1-4
Author(s):  
Dan-Qing Xue ◽  
Lan Yang

Focal nodular hyperplasia (FNH) is the second most common liver cell-derived benign tumor. It is postulated that chemotherapy-induced hepatic circulatory abnormalities, like sinusoidal obstruction syndrome (SOS), could lead to the development of FNH. Cyclophosphamide was also reported to induce SOS in a synergistic effect with total body irradiation. However, none of cyclophosphamide-related FNH had ever been reported before. In this case report, we present a female patient who was treated with neoadjuvant chemotherapy of cyclophosphamide (500mg/m2)-docetaxel (75mg/m2)-pharmorubicin (90mg/m2) regimen every 3 weeks for breast cancer developed FNH after 4 courses of treatment. The patient had no chronic liver disease, no history of smoking, drinking, or medication use. The chronological correlation between the chemotherapy and the appearance of the FNH suggested a cause-effect association. Therefore, this is the first case report about development of FNH after cyclophosphamide-based chemotherapy. Taking into account the frequency of breast cancer, it is instructive to recognize such observation of FNH in the context to make the differential diagnosis with hepatic metastasis.


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