Investigation of the Utility of an In Vitro Release Test for Optimizing Semisolid Dosage Forms

2001 ◽  
Vol 6 (3) ◽  
pp. 469-476 ◽  
Author(s):  
Stefan Proniuk ◽  
Sarah E. Dixon ◽  
James Blanchard
Keyword(s):  
In Vitro Release ◽  
Dosage Forms ◽  
Release Test ◽  
Vitro Release

Evaluation of the in vitro release and permeation of Cordia verbenacea DC essential oil from topical dosage forms

2019 ◽  
Vol 53 ◽  
pp. 101173 ◽  
Author(s):  
Jéssica Domingos da Silva ◽  
Márcio Vinícius Gomes ◽  
Lucio Mendes Cabral ◽  
Valeria Pereira de Sousa
Keyword(s):  
Essential Oil ◽  
In Vitro Release ◽  
Dosage Forms ◽  
Topical Dosage ◽  
Vitro Release ◽  
Topical Dosage Forms

Preparation and in vitro Release Test of Insulin Loaded W/O Microemulsion

2008 ◽  
Vol 29 (5) ◽  
pp. 756-762 ◽  
Author(s):  
Jian‐Lei Wang ◽  
Zheng‐Wu Wang ◽  
Feng Liu ◽  
Da‐Yun Zhao
Keyword(s):  
In Vitro Release ◽  
Release Test ◽  
Vitro Release

scholarly journals A comprehensive approach to qualify and validate the essential parameters of an in vitro release test (IVRT) method for acyclovir cream, 5%

2018 ◽  
Vol 535 (1-2) ◽  
pp. 217-227 ◽  
Author(s):  
Katrin I. Tiffner ◽  
Isadore Kanfer ◽  
Thomas Augustin ◽  
Reingard Raml ◽  
Sam G. Raney ◽  
...  
Keyword(s):  
In Vitro Release ◽  
Comprehensive Approach ◽  
Release Test ◽  
Vitro Release ◽  
Acyclovir Cream

scholarly journals FIP/AAPS Guidelines for Dissolution/In Vitro Release Testing of Novel/Special Dosage Forms*

2003 ◽  
Vol 10 (1) ◽  
pp. 6-15 ◽  
Author(s):  
Martin Siewert ◽  
Jennifer Dressman ◽  
Cynthia Brown ◽  
Vinod Shah
Keyword(s):  
In Vitro Release ◽  
Dosage Forms ◽  
Dissolution In Vitro ◽  
Vitro Release ◽  
Release Testing

scholarly journals Meeting Report: FIP/AAPS Joint Workshop Report: Dissolution/In Vitro Release Testing of Novel/Special Dosage Forms

2011 ◽  
Vol 18 (4) ◽  
pp. 51-64 ◽  
Author(s):  
Cynthia K. Brown ◽  
Horst Dieter Friedel ◽  
Amy R. Barker ◽  
Lucinda F. Buhse ◽  
Susanne Keitel ◽  
...  
Keyword(s):  
In Vitro Release ◽  
Dosage Forms ◽  
Meeting Report ◽  
Workshop Report ◽  
Joint Workshop ◽  
Dissolution In Vitro ◽  
Vitro Release ◽  
Release Testing

In Vitro Release Test of Nano-drug Delivery Systems Based on Analytical and Technological Perspectives

2019 ◽  
Vol 15 (4) ◽  
pp. 373-409 ◽  
Author(s):  
Emirhan Nemutlu ◽  
İpek Eroğlu ◽  
Hakan Eroğlu ◽  
Sedef Kır
Keyword(s):  
Drug Delivery ◽  
Analytical Method ◽  
Drug Delivery Systems ◽  
In Vitro Release ◽  
Delivery Systems ◽  
Method Selection ◽  
Release Test ◽  
Nano Drug Delivery ◽  
Vitro Release

Background:Nanotech products are gaining more attention depending on their advantages for improving drug solubility, maintenance of drug targeting, and attenuation of drug toxicity. In vitro release test is the critical physical parameter to determine the pharmaceutical quality of the product, to monitor formulation design and batch-to-batch variation.Methods:Spectrophotometric and chromatographic methods are mostly used in quantification studies from in vitro release test of nano-drug delivery systems. These techniques have advantages and disadvantages with respect to each other considering dynamic range, selectivity, automation, compatibility with in vitro release media and cost per sample.Results:It is very important to determine the correct kinetic profile of active pharmaceutical substances. At this point, the analytical method used for in vitro release tests has become a very critical parameter to correctly assess the profiles. In this review, we provided an overview of analytical methods applied to the in vitro release assay of various nanopharmaceuticals.Conclusion:This review presents practical direction on analytical method selection for in vitro release test on nanopharmaceuticals. Moreover, precautions on analytical method selection, optimization and validation were discussed.

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