Five-year follow-up of low-level laser therapy (LLLT) in patients with age-related macular degeneration (AMD)

Objective: A pressure ulcer (PU) is an area of tissue trauma caused by continuous and prolonged pressure, often associated with hospitalised patients immobilised due to neurological problems, negatively affecting their quality of life, and burdening the public budget. The aim of this study was to report the follow-up, for 45 weeks, of three patients with neurological lesions due to trauma who subsequently developed PUs, and who were treated with a combination of photodynamic therapy (PDT), low level laser therapy (LLLT) and cellulose membrane (CM). Method: PDT was mediated by the photosensitiser curcumin on a 1.5% emulsion base. Blue LED light at 450 nm was delivered continuously for 12 minutes at an irradiance of 30mW/cm2 and total energy delivered to the tissue was 22J/cm2. LLLT was performed with 660 nm laser, punctuated and continuous, twice a week with parameters: spot size 0.04cm2, power of 40mW, 10 seconds per point, fluence of 10J/cm2 and irradiance of 1000mW/cm2. Results: All PUs had a significant reduction (range: 95.2–100%) of their area after 45 weeks of follow-up and two PUs had complete healing at 20 weeks and 30 weeks. All of the PUs showed a reduction in contamination with the PDT treatments in different proportions. Conclusion: From the results obtained, we conclude that the combination of PDT, LLLT and CM is a promising treatment for PU healing.

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Efficacy of Low-Level Laser Therapy in Treatment of Recurrent Aphthous Ulcers – A Sham Controlled, Split Mouth Follow Up Study

JOURNAL FOR CLINICAL AND DIAGNOSTIC RESEARCH ◽

10.7860/jcdr/2014/7639.4064 ◽

2014 ◽

Cited By ~ 5

Author(s):

Hersheal Aggarwal

Keyword(s):

Laser Therapy ◽

Low Level Laser Therapy ◽

Low Level ◽

Follow Up Study ◽

Low Level Laser ◽

Aphthous Ulcers ◽

Level Laser ◽

Recurrent Aphthous Ulcers

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Efficacy of Nonsurgical Mechanical Debridement With and Without Adjunct Low-Level Laser Therapy in the Treatment of Peri-Implantitis: A Randomized Controlled Trial

Journal of Oral Implantology ◽

10.1563/aaid-joi-d-19-00367 ◽

2020 ◽

Vol 46 (5) ◽

pp. 526-531 ◽

Cited By ~ 1

Author(s):

Fawaz Alqahtani ◽

Nasser Alqhtani ◽

Sree Lalita Celur ◽

Darshan Devang Divakar ◽

Abdulaziz A. Al-Kheraif ◽

...

Keyword(s):

Bone Resorption ◽

Laser Therapy ◽

Low Level Laser Therapy ◽

Periodontal Pocket ◽

Low Level ◽

Low Level Laser ◽

Probing Depth ◽

Level Laser ◽

Significant Difference

We hypothesized that in the long term (6-month follow-up), nonsurgical mechanical debridement (NSMD) with adjunct low-level laser therapy (LLLT) is more effective for the treatment of peri-implantitis than NSMD alone. The aim of the present 6-month follow-up convenience-sample cohort study was to assess the efficacy of LLLT as an adjunct to NSMD in the treatment of peri-implantitis. A questionnaire was used to collect demographic information. Patients with peri-implantitis in the test and control groups underwent NSMD with and without adjunct LLLT, respectively. Randomization was done by tossing a coin. In the test group, the laser was applied perpendicular to the periodontal pocket for 20 seconds at a constant distance of 15 mm and with a continuous wavelength (3.41 J/cm2 delivery with a 1.76 cm2 spot and average output of 0.3 W). In both groups, peri-implant probing depth, bleeding upon probing, and crestal bone resorption were assessed at baseline and at the 3-month and 6-month follow-up. Group comparisons were performed, and P < .05 was considered statistically significant. Sixty-seven individuals with peri-implantitis were included. The mean age of participants who underwent NSMD with adjunct LLLT and NSMD alone was 46.5 ± 3.4 and 45.3 ± 1.1 years, respectively. At the 3- and 6-month follow-up, peri-implant (P < .05), bleeding upon probing (P < .05), and probing depth (P < .05) were significantly higher among patients who underwent NSMD alone compared with patients who underwent NSMD with adjunct LLLT. There was no significant difference in crestal bone resorption in all patients up to the 6-month follow-up. In the short term, NSMD with adjunct LLLT was a useful treatment protocol for the treatment of peri-implant soft-tissue inflammation.

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The effect of low level laser therapy (LLLT) on bone remodelling after median diastema closure: A one year and half follow-up study

Orthodontic Waves ◽

10.1016/j.odw.2009.02.001 ◽

2009 ◽

Vol 68 (3) ◽

pp. 116-122 ◽

Cited By ~ 9

Author(s):

Sherif Essam Zahra ◽

Abbadi Adel Elkasi ◽

Mouchira Salah Eldin ◽

Vaska Vandevska-Radunovic

Keyword(s):

Laser Therapy ◽

Bone Remodelling ◽

Low Level Laser Therapy ◽

Low Level ◽

Follow Up Study ◽

Low Level Laser ◽

Level Laser ◽

One Year

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Low-Level Laser Therapy for Temporomandibular Disorders: A Systematic Review with Meta-Analysis

Pain Research and Management ◽

10.1155/2018/4230583 ◽

2018 ◽

Vol 2018 ◽

pp. 1-13 ◽

Cited By ~ 18

Author(s):

Gang-Zhu Xu ◽

Jie Jia ◽

Lin Jin ◽

Jia-Heng Li ◽

Zhan-Yue Wang ◽

...

Keyword(s):

Systematic Review ◽

Laser Therapy ◽

Methodological Quality ◽

Low Level Laser Therapy ◽

Low Level ◽

Low Level Laser ◽

Jadad Scale ◽

Level Laser

Objectives. We systematically reviewed randomized controlled trials (RCTs) of the effect of low-level laser therapy (LLLT) versus placebo in patients with temporomandibular disorder (TMD). Methods. A systematic search of multiple online sources electronic databases was undertaken. The methodological quality of each included study was assessed using the modified Jadad scale, and the quality of evidence was evaluated using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) system. Results. A total of 31 RCTs were included. Total modified Jadad scale scores showed that the methodological quality was high in 30 studies and low in 1 study. Combining data from all clinically heterogeneous studies revealed positive effects of LLLT on pain relief, regardless of the visual analogue scale (VAS) score or the change of VAS score between the baseline and the final follow-up time point, while dosage analyses showed discrepant results about the effects of high or low doses for patients with TMD. Follow-up analyses showed that LLLT significantly reduced pain at the short-term follow-up. Temporomandibular joint function outcomes indicated that the overall effect favored LLLT over placebo. Conclusion. This systematic review suggests that LLLT effectively relieves pain and improves functional outcomes in patients with TMD.

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