ETUDE DE LA CAPACITE DUNE PHOTOPILE AU SILICIUM A JONCTIONS VERTICALES SERIES SOUS ECLAIREMENT MONOCHROMATIQUE

Ce travail consiste a faire une etude de la capacite de la photopile a jonction verticale serie sous eclairement monochromatique en tenant compte de la longueur donde et de la profondeur. Lequation de continuite, traduisant, les phenomenes de generation, de diffusion et de recombinaison des porteurs de charge photogeneres dans la base de la photopile est resolue en tenant compte des vitesses de recombinaison a la jonction et en face arriere. Une etude de la capacite de diffusion en fonction des vitesses de recombinaison a la jonction base-emetteur mais aussi en fonction de la phototension a permis de determiner une capacite initiale Co, pour differentes longueurs donde de leclairement incident et pour differentes valeurs de la profondeur.

STUDY OF ANTIBIOTIC-RESISTANCE AND SENSITIVITY PATTERN IN A TERTIARY CARE TEACHING HOSPITAL

Introduction: Antibiotics are helpful in bacterial infection control and management. Irrational antibiotic use leads to resistance, which puts modern medicines achievements at risk. This study aims to know antibiotic resistance and sensitivity patterns and to assess possible factors that favor the development of antibiotic resistance. Methods: It is a retrospective observational study. Data collected from June 2019 to May 2020 from the culture & sensitivity records of various clinical isolates at the Microbiology department of SMC, Vijayawada, and analyzed by descriptive statistics. Results: Total samples collected 2905. Only746 samples showed significant growth. Most commonly, isolated organisms were from Pus and Body fluids Staphylococcus aureus (31.16%), Klebsiella (23.02%), from blood samples Staphylococcus aureus (44%,) Klebsiella (32%), from urine samples Escherichia coli (27.31%),Staphylococcus aureus (16.66%). Bacteria isolated from, Blood and Pus & body fluid samples showed more resistance to Amoxicillin + Clavulanic acid, 60% &58.60%, and urine samples showed more resistance to Norfloxacin69.44%. Conclusion: In this study, bacteria isolated from, blood, pus, and body fluid samples showed more resistance to Amoxicillin + Clavulanic acid, from urine samples showed more resistance to Norfloxacin. Parenterally used drugs like aminoglycosides and vancomycin have retained their sensitivity but bacteria also showed resistance to Imipenem, Vancomycin, new combinations like Cefoperazone + Sulbactam. A culture & sensitivity test and following antibiotic stewardship guidelines before prescribing antibiotics will give good results to prevent antibiotic resistance.

FORMATION OF PROFESSIONAL COMMUNICATIVE COMPETENCE OF STUDENTS OF ECONOMIC SPECIALTIES (IN THE PROCESS OF LEARNING ENGLISH)

At present, the system of general and vocational education is undergoing fundamental changes, as never before, orient specialists towards creativity in their professional activities. The main goal of modern vocational education is to train a qualified, competent specialist who is ready to work in an increasingly competitive labor market. Modern professional activity imposes special requirements on the communicative training of specialists, which is manifested in the ability to negotiate, conduct a dialogue, correlate linguistic means with the tasks and conditions of learning, take into account social norms of behavior and the communicative expediency of statements.

ANABOLIC STEROID ABUSE AND CARDIOVASCULAR TOXICITY: CASE REPORT

Despite the development of tests for the detection of doping, Anabolic steroids, are still used to increase sports performance. Unfortunately, studies have clearly shown that overdose of anabolic steroids can induce serious cardiovascular complications that can be life-threatening. This implies the determining role of health professionals in informing the general population and athletes in particular about the lethal effect of these substances. We report the case of a young high-level athlete who consults for palpitations and in whom cardiac imaging reveals abnormalities related to chronic consumption of anabolic steroids.

IMPROVING THE EFFECTIVENESS OF TEACHING STUDENTS A FOREIGN LANGUAGE BASED ON A COMMUNICATIVE METHODOLOGY

In the context of globalization and integration in the country into the international community, the modernization of foreign language teaching in domestic higher education is taking place. The development of international contacts in the country causes a need for specialists of various profiles who are well-versed in foreign languages, but their training does not always give the desired results. Practice has shown that the grammatical translation method used in the last few decades to teach a foreign language to specialists of various profiles, in which the emphasis is on learning rules and translating texts, rather than on communication, has not fully justified itself. Having generally good grammar knowledge, and skills in the field of translation, graduates of non-linguistic universities have difficulties in communication with foreigners in the course of professional activities, and the question about the level of knowledge of foreign language professionals are increasingly responsible read and translate with a dictionary, which actually means no possession and failure to carry out practical communication in a foreign language.

FORMULATION AND INVITRO EVALUATION OF SOLID DISPERSION TABLETS OF SILYMARIN

Objective: The research aims to formulate and evaluate Solid Dispersion tablets of Silymarin. Methods: Solid dispersions of Silymarin were prepared with various concentrations of carriers by using solvent evaporation method. The prepared solid dispersions were compressed into tablets by using 8 mm punch rotary tablet punching machine, with the hardness of 3.5kg /cm2.The formulated tablets were evaluated for various quality control parameters. Results: Silymarin was mixed with various proportions of excipients which showed no drug-excipients interactions. The precompression blend of Silymarin solid dispersions were characterized with respect to angle of repose, bulk density, tapped density, Carrs index and Hausners ratio. The precompression blend of all the batches indicated good to fair flowability and compressibility. Conclusion: The tablet passed all the tests. Among all the formulations F4 formulation containing, Drug and PEG 4000 in the ratio of 1:4 showed good result that is 94.95 % in 60 minutes. As the concentration of polymer increased the drug release was increased. While the formulations containing PEG 6000 showed less release. Hence from the dissolution data it was evident that F4 formulation is the better formulation.

OCULAR CLINICAL PROFILE OF PATIENTS WITH PSEUDOEXFOLIATION SYNDROME AND PSEUDOEXFOLIATION GLAUCOMA AT TERTIARY CARE CENTRE IN KASHMIR

Aim: To study the clinical profile of pseudoexfoliation (PEX) syndrome and Pseudoexfoliation glaucoma at tertiary care centre in Kashmir. Materials and Methods: A cross sectional study consisting of 100 PEX and 100 PEXG patiens, attending the general ophthalmology clinic of a tertiary care center in kashmir. All patients underwent a complete ophthalmologic evaluation including recording IOP,gonioscopy and Central Corneal Thickness(CCT). Results: The study cohort comprised 200 patients(100 with PEX and 100 with PEXG). There were 145(72.5) males and 55(27.5%) females. The highest number of patients (120 patients) were from the age group between 61 and 70years. 145(72.5%) patients were involved in outdoor activities.153(76.5%) patients had bilateral involvement of pseudoexfoliationand pseudoexfoliative material was present at anterior lens capsule in 175(49.58%) eyes. Nuclear cataract was predominant type of cataract and was present in 188(48.2%)eyes. Mean IOP was 17.26±7.634mmHg in PEX group and 24.39±4.456mmHg in PEXG group. Gonioscopyshowed open angles in 96.5% of eyes and occludable in 3.5% eyes . Mean central corneal thickness was 531.80±19.127μm. Conclusion: The prevalence of PEX is found to increase with age. Patients with PXG had more severity of optic nerve damage at presentation. Therefore a careful assessment for detection of PEX is warranted and regular follow-up of patients is desired to minimize the extent of optic nerve damage.

ARTIFICIAL FIELD INOCULATION OFBREAD WHEAT ADVANCED LINES WITH TILLETIAINDICA, CAUSAL AGENT OF KARNAL BUNT

The reaction to Tilletiaindica of one thousand and ninety twobread wheat advanced lines were evaluated in the field during the crop season 2016-2017. Sowing in beds with two rows was carried out on November 11 and 24, 2016, using 8 g of seed. Five spikes per line were inoculated by injection with 1 mL of an allantoidsporidial suspension (10,000/mL) during the boot stage, and at maturity the percentage of infection was determined by counting healthy and infected grains. The range of infection in the first date was 0-88.83 with a mean of 31.81%, while in the second date it was 0-82.65% with a mean of 24.44%.The range of infection of the two dates was 0.46-83.71% with a mean of 28.12%.Sixteenlines showed a percentage of infection equal or below 5.0% in both dates, and out of those lines, the following five showed less than 2.5%: two sister lines of MUNAL#1/FRANCOLIN#1*2/3/ATTILA*2/PBW65//MURGA(CMSS12Y00701T-099TOPM-099Y-099M-0SY-13M-0WGY), MUNAL#1/FRANCOLIN#1*2/3/ATTILA*2/PBW65//MURGA (CMSS12Y00701T-099TOPM-099Y-099M-0SY-17M-0WGY), BAJ#1/3/KIRITATI//ATTILA*2/PASTOR*2/4/MUTUS*2/TECUE#1, VILLAJUAREZF2009/6/ATTILA/3*BCN//BAV92/3/PASTOR/4/TACUPETOF2001*2/BRAMBLING/5/PAURAQ, and KACHU/BECARD//WBLL1*2/BRAMBLING/4/FRET2/TUKURU//FRET2/3/MUNAL#1. Lines with the highest percentage of infection were: BABAX/LR42//BABAX*2/3/KUKUNA/4/CROSBILL#1/5/BECARD/6/KSW/SAUAL//SAUAL/7/BABAX/LR42//BABAX*2/3/KUKUNA/4/CROSBILL#1/5/BECARD with 88.83 in the first date,MUU/KBIRD//2*KACHU/KIRITATIwith 84.77 and 82.65%in the first and second date, respectively, and TACUPETOF2001*2/BRAMBLING//WBLL1*2/BRAMBLING/6/WBLL1*2/KURUKU*2/5/REH/HARE//2*BCN/3/CROC_1/AE.SQUARROSA(213)//PGO/4/HUITES/7/BAV92//IRENA/KAUZ/3/HUITES/4/2*ROLF07 with 81.67% in the first date. The average of the three highest levels of infection of the susceptible checkwas99.7%.

ANTIOXIDANT PROPERTIES OF METHANOLIC EXTRACT OF BRYPHYLLUM PINNATUM ON ALBINO WISTAR RATS

Bryophyllumpinnatum, which belong to the family Crassulceae, is a succulent plant native to Madagascar, which is a popular houseplant and has become naturalized in tropical and subtropical areas. It has been in traditional medicine for the treatment of hypertension and kidney stones. Despite these acclaimed efficacies of its use in trado-medical practices, the effects on body organs are not well understood. The aim of this study was to evaluate antioxidant properties of Bryophyllumpinnatum. Fifteen adult Sprague dowley rats were use in this study split into three groups (group 1, 2 and 3). Group 1 animals served as the control, while group 2 and 3 served as the experimental groups. Acute toxicity, and antioxidants. The result of this study found LD50 to be above 5000mg/kg. In vitro antioxidant test found the presence of alkaloids, saponins, thiamin, riboflavin etc. Antioxidant activity test result found an increase in GSH, GPx, a decrease in MDA and a stable CAT. In conclusion, we recommend its uses in human, but at a regulated doses because of its efficacy as stated in this study.

HOLISTIC DENTAL APPROACH FOR VISUALLY IMPAIRED CHILDREN: A NARRATIVE REVIEW

Visual impairment is one of the most common disabilty. It requires a lot of attention especially in the field of dentistry. These children are often deprived of oral health care needs due to dental neglect. This is a comprehensive review that focuses on prevalence, etiology as well as treatment modalities for these children. It comprises barriers to dental health and various methods which can be used to overcome the challenges.