Platelet Activation Through the Efficacy of Aspirin in Congenital Heart Disease Patients Undergoing Transcatheter Closure of Atrial Septal Defects or Ventricular Septal Defects

2014 ◽  
Vol 18 (12) ◽  
pp. 832-838 ◽  
Author(s):  
Gang Pan ◽  
Zhao-Feng Xie ◽  
Ying Zhang ◽  
Sheng-Chun Long ◽  
Xi-Ping Xu ◽  
...  
Author(s):  
Khoa Nguyen ◽  
Patrick Callahan

The term congenital heart disease encompasses a vast array of lesions that present unique anesthetic challenges. Making up close to 10% of all congenital heart disease, atrial septal defects are some of the more commonly encountered congenital lesions. Atrial chambers in the heart are separated by a septum that forms during embryological development. When the septum does not develop normally, blood communicates between the right and left atria. This alteration in flow has significant effects on both cardiac and pulmonary anatomy and physiology. Cardiothoracic surgery used to be the only way to close defects that did not spontaneously close. Transcatheeter device closure of atrial septal defects in the cardiac catheterization lab has become increasingly common and offers significant advantages over open heart surgery. This chapter highlights the anatomic and physiologic considerations of the different types of atrial septal defects and discusses the details of transcatheter closure including indications, timing, and risks.


2020 ◽  
pp. 743-790

This chapter deals with the role of echocardiography in congenital heart disease. It covers views and findings, sequential segmental analysis, atrial septal defects and patent foramen ovale, atrial septal defects, ventricular septal defects, assessment of ventricular septal defects, left ventricular outflow and inflow obstruction, right ventricular outflow obstruction, transposition of the great arteries, persistent left superior vena cava, anomalous pulmonary drainage, tetralogy of Fallot, truncus arteriosus, double outlet right ventricle, single ventricle, surgical correction of congenital heart disease, Ebstein’s anomaly, patent ductus arteriosus, aortic coarctation, sinus of Valsalva aneurysm, Marfan syndrome, and congenital pericardial disease


2020 ◽  
Vol 16 (4) ◽  
pp. 317-342 ◽  
Author(s):  
Robert J Henning

Approximately 50 million adults worldwide have known congenital heart disease (CHD). Among the most common types of CHD defects in adults are atrial septal defects and ventricular septal defects followed by complex congenital heart lesions such as tetralogy of Fallot. Adults with CHDs are more likely to have hypertension, cerebral vascular disease, diabetes and chronic kidney disease than age-matched controls without CHD. Moreover, by the age of 50, adults with CHD are at a greater than 10% risk of experiencing cardiac dysrhythmias and approximately 4% experience sudden death. Consequently, adults with CHD require healthcare that is two- to four-times greater than adults without CHD. This paper discusses the diagnosis and treatment of adults with atrial septal defects, ventricular septal defects and tetralogy of Fallot.


2013 ◽  
Vol 24 (5) ◽  
pp. 866-871 ◽  
Author(s):  
Dorra Abid ◽  
Anis Elloumi ◽  
Leila Abid ◽  
Souad Mallek ◽  
Hajer Aloulou ◽  
...  

AbstractAim: To investigate the previously unknown birth incidence, treatment, and mortality of children with congenital heart disease in Tunisia. Methods: We undertook a retrospective review of medical records of all patients who were born in 2010 and 2011, and were diagnosed in Sfax (Tunisia) with congenital heart defect. Results: Among 37,294 births, 255 children were detected to have congenital heart disease, yielding a birth incidence of 6.8 per 1000. The most frequently occurring conditions were ventricular septal defects (31%), ostium secundum atrial septal defects (12.9%), and pulmonary valve abnormalities (12%). Coarctation of the aorta, tetralogy of Fallot, univentricular physiology, pulmonary atresia with ventricular septal defect, and transposition of the great arteries were found in 4.3%, 6.2%, 3.4%, 2.7%, and 2.7%, respectively. During the follow-up of 1 year, 23% of the children died. About three-quarters of those deaths happened before surgery. Conclusion: The present study is in line with the general estimates in the world. It has revealed a high case of mortality among the patients awaiting corrective surgery. These children need more facilities.


1993 ◽  
Vol 14 (12) ◽  
pp. 488-494

Trisomy 21, Down syndrome, is one of a number of chromosomal abnormalities associated with congenital heart disease. Recent studies indicate that approximately 5% of all congenital heart defects are associated with some form of chromosomal abnormality, the majority of which are Down syndrome. Reports of the incidence of congenital heart disease in patients who have Down syndrome have varied, but it is commonly accepted to be 50%. Endocardial cushion defect and ventricular septal defects both have been reported as the "most common," but the majority of investigators accept the endocardial cushion defect as being the more frequent. The association between endocardial cushion defects and Down syndrome is so striking that when an endocardial cushion defect is diagnosed in an infant, the possibility of Down syndrome always should be considered.


PEDIATRICS ◽  
1967 ◽  
Vol 39 (5) ◽  
pp. 794-795
Author(s):  
NORMAN J. SISSMAN

The "controversy" over treatment of infants with ventricular septal defects published in the January 1967 issue of Pediatrics prompts me to comment on one general factor, vital in decisions between alternative methods of treatment of congenital heart disease, which has received little attention in the literature—namely, the experiences and capabilities of individual surgical teams. That Dr. Nadas takes this into account is reflected in his statements, ". . . our surgeons have been able to accomplish [banding of the pulmonary artery] at a mortality rate of 10% or less . . ." and ". . . the pediatrician unless he has surgeons with exceptional ability at his disposal, will do better to . . . proceed conservatively."


2017 ◽  
Author(s):  
Susan E. Haynes ◽  
Heather L. Bartlett ◽  
David J Skorton ◽  
Luke J Lamers

With advances in medical and surgical care, an increasing number of children with congenital diseases of the heart and vasculature now survive to adulthood. The proportion of adults who are affected by congenital heart disease is expected to continue to increase. Thus, it is important for clinicians to be knowledgeable about the care of these patients. This review examines acyanotic disorders (shunts and valvular lesions), vascular anomalies, cyanotic disorders, and women’s health issues. Figures show the anatomy of atrial septal defects, transcatheter closure of atrial septal defects, an anatomic cross section showing the atrioventricular septum, the anatomic positions of ventricular septal defects, a computed tomography scan of aortic coarctation, angiogram of a persistent left superior vena cava draining into the right atrium, systemic artery-to-pulmonary artery shunts, magnetic resonance image of a patient with repaired tetralogy of Fallot and long-standing pulmonary valve insufficiency, treatment of pulmonary valve regurgitation with a transcatheter pulmonary valve, computed tomographic images of a patient with atrial switch palliation of transposition of the great arteries and multiple baffle obstructions, stages in the repair of functional single ventricles, and echocardiograms of a patient with Ebstein anomaly. Tables list recommendations for pulmonary valve replacement in repaired tetralogy of Fallot, conditions in which pregnancy is high risk, and cardiac indications for fetal echocardiography. This review contains 12 highly rendered figures, 4 tables, and 62 references.


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