Gene Therapy for Bone Repair Using Human Cells: Superior Osteogenic Potential of Bone Morphogenetic Protein 2–Transduced Mesenchymal Stem Cells Derived from Adipose Tissue Compared to Bone Marrow

Sofia Bougioukli; Osamu Sugiyama; William Pannell; Brandon Ortega; Matthew H. Tan; Amy H. Tang; Robert Yoho; Daniel A. Oakes; Jay R. Lieberman

doi:10.1089/hum.2017.097

Gene Therapy for Bone Repair Using Human Cells: Superior Osteogenic Potential of Bone Morphogenetic Protein 2–Transduced Mesenchymal Stem Cells Derived from Adipose Tissue Compared to Bone Marrow

Human Gene Therapy ◽

10.1089/hum.2017.097 ◽

2018 ◽

Vol 29 (4) ◽

pp. 507-519 ◽

Cited By ~ 16

Author(s):

Sofia Bougioukli ◽

Osamu Sugiyama ◽

William Pannell ◽

Brandon Ortega ◽

Matthew H. Tan ◽

...

Keyword(s):

Stem Cells ◽

Gene Therapy ◽

Bone Marrow ◽

Mesenchymal Stem Cells ◽

Adipose Tissue ◽

Bone Morphogenetic Protein ◽

Bone Repair ◽

Bone Morphogenetic Protein 2 ◽

Osteogenic Potential ◽

Morphogenetic Protein

Enhancement of ectopic bone formation by bone morphogenetic protein-2 delivery using heparin-conjugated PLGA nanoparticles with transplantation of bone marrow-derived mesenchymal stem cells

Journal of Biomedical Science ◽

10.1007/s11373-008-9277-4 ◽

2008 ◽

Vol 15 (6) ◽

Cited By ~ 47

Author(s):

Sung Eun Kim ◽

Oju Jeon ◽

Jung Bok Lee ◽

Min Soo Bae ◽

Heoung-Jae Chun ◽

...

Keyword(s):

Stem Cells ◽

Bone Marrow ◽

Mesenchymal Stem Cells ◽

Bone Formation ◽

Bone Morphogenetic Protein ◽

Plga Nanoparticles ◽

Ectopic Bone Formation ◽

Bone Morphogenetic Protein 2 ◽

Morphogenetic Protein ◽

Ectopic Bone

The Additive Effect of Mesenchymal Stem Cells and Bone Morphogenetic Protein 2 on γ-Irradiated Bone Marrow in Mice

Cell Biochemistry and Biophysics ◽

10.1007/s12013-011-9236-y ◽

2011 ◽

Vol 61 (3) ◽

pp. 539-550 ◽

Cited By ~ 1

Author(s):

Shuibing Liu ◽

Peizhen Hu ◽

Ying Hou ◽

Peng Li ◽

Xubo Li ◽

...

Keyword(s):

Stem Cells ◽

Bone Marrow ◽

Mesenchymal Stem Cells ◽

Bone Morphogenetic Protein ◽

Additive Effect ◽

Bone Morphogenetic Protein 2 ◽

Morphogenetic Protein

The effect of recombinant human bone morphogenetic protein-2 on the osteogenic potential of rat mesenchymal stem cells after several passages

Acta Orthopaedica ◽

10.1080/17453670710013816 ◽

2007 ◽

Vol 78 (2) ◽

pp. 285-292 ◽

Cited By ~ 28

Author(s):

Hisato Ishikawa ◽

Hiroshi Kitoh ◽

Fumiaki Sugiura ◽

Naoki Ishiguro

Keyword(s):

Stem Cells ◽

Mesenchymal Stem Cells ◽

Bone Morphogenetic Protein ◽

Human Bone ◽

Bone Morphogenetic Protein 2 ◽

Osteogenic Potential ◽

Morphogenetic Protein ◽

Human Bone Morphogenetic Protein ◽

Recombinant Human Bone

Human bone marrow-derived mesenchymal stem cells and osteoblast differentiation on titanium with surface-grafted chitosan and immobilized bone morphogenetic protein-2

Journal of Materials Science Materials in Medicine ◽

10.1007/s10856-008-3528-9 ◽

2008 ◽

Vol 20 (1) ◽

pp. 1-10 ◽

Cited By ~ 41

Author(s):

Tee Yong Lim ◽

W. Wang ◽

Zhilong Shi ◽

Chye Khoon Poh ◽

K. G. Neoh

Keyword(s):

Stem Cells ◽

Bone Marrow ◽

Mesenchymal Stem Cells ◽

Bone Morphogenetic Protein ◽

Osteoblast Differentiation ◽

Human Bone ◽

Human Bone Marrow ◽

Bone Morphogenetic Protein 2 ◽

Morphogenetic Protein

Limited but heterogeneous osteogenic response of human bone marrow mesenchymal stem cells to bone morphogenetic protein-2 and serum

Growth Factors ◽

10.3109/08977190903326362 ◽

2009 ◽

Vol 28 (1) ◽

pp. 34-43 ◽

Cited By ~ 20

Author(s):

Daiki Mizuno ◽

Hideki Agata ◽

Hiroki Furue ◽

Ayuko Kimura ◽

Yuji Narita ◽

...

Keyword(s):

Stem Cells ◽

Bone Marrow ◽

Mesenchymal Stem Cells ◽

Bone Morphogenetic Protein ◽

Human Bone ◽

Human Bone Marrow ◽

Bone Morphogenetic Protein 2 ◽

Morphogenetic Protein ◽

Osteogenic Response ◽

Marrow Mesenchymal Stem Cells

Corrigendum to “Bacitracin promotes osteogenic differentiation of human bone marrow mesenchymal stem cells by stimulating the bone morphogenetic protein-2/ Smad axis” [Biomed. Pharmacother. 103 (2018) 588–597]

Biomedicine & Pharmacotherapy ◽

10.1016/j.biopha.2021.112575 ◽

2021 ◽

pp. 112575

Author(s):

Hui Li ◽

Bin'en Nie ◽

Zhe Du ◽

Shutao Zhang ◽

Teng Long ◽

...

Keyword(s):

Stem Cells ◽

Bone Marrow ◽

Mesenchymal Stem Cells ◽

Osteogenic Differentiation ◽

Bone Morphogenetic Protein ◽

Human Bone ◽

Human Bone Marrow ◽

Bone Morphogenetic Protein 2 ◽

Morphogenetic Protein ◽

Marrow Mesenchymal Stem Cells

Bone morphogenetic protein-2 enhances bone regeneration mediated by transplantation of osteogenically undifferentiated bone marrow-derived mesenchymal stem cells

Biotechnology Letters ◽

10.1007/s10529-008-9675-8 ◽

2008 ◽

Vol 30 (7) ◽

pp. 1163-1168 ◽

Cited By ~ 21

Author(s):

Sun-Woong Kang ◽

Wan-Geun La ◽

Jin Muk Kang ◽

Jung-Ho Park ◽

Byung-Soo Kim

Keyword(s):

Stem Cells ◽

Bone Marrow ◽

Mesenchymal Stem Cells ◽

Bone Regeneration ◽

Bone Morphogenetic Protein ◽

Bone Morphogenetic Protein 2 ◽

Morphogenetic Protein

Bone morphogenetic protein-2 in biodegradable gelatin and β-tricalcium phosphate sponges enhances the in vivo bone-forming capability of bone marrow mesenchymal stem cells

Journal of Tissue Engineering and Regenerative Medicine ◽

10.1002/term.427 ◽

2011 ◽

Vol 6 (4) ◽

pp. 253-260 ◽

Cited By ~ 24

Author(s):

Mika Tadokoro ◽

Asako Matsushima ◽

Noriko Kotobuki ◽

Motohiro Hirose ◽

Yu Kimura ◽

...

Keyword(s):

Stem Cells ◽

Bone Marrow ◽

Mesenchymal Stem Cells ◽

Bone Morphogenetic Protein ◽

Tricalcium Phosphate ◽

Bone Morphogenetic Protein 2 ◽

Morphogenetic Protein ◽

Marrow Mesenchymal Stem Cells

549. Bone Morphogenetic Protein-2 Gene Therapy on Ovariectomized Mice Model Using Ex Vivo Modified Mesenchymal Stem Cells

Molecular Therapy ◽

10.1016/s1525-0016(16)44755-6 ◽

2007 ◽

Vol 15 ◽

pp. S211

Keyword(s):

Stem Cells ◽

Gene Therapy ◽

Mesenchymal Stem Cells ◽

Bone Morphogenetic Protein ◽

Ex Vivo ◽

Bone Morphogenetic Protein 2 ◽

Mice Model ◽

Ovariectomized Mice ◽

Morphogenetic Protein

In vitro construction of tissue-engineered bone with bone morphogenetic protein-2-transfected rabbit bone marrow mesenchymal stem cells and hydroxyapatite nanocomposite

nano Online ◽

10.1515/nano.0007.00013 ◽

2016 ◽

Author(s):

Chunlei He ◽

Cheng He ◽

Jianwen Mo ◽

Xiaona Fan ◽

Guanglin Ji ◽

...

Keyword(s):

Stem Cells ◽

Bone Marrow ◽

Mesenchymal Stem Cells ◽

Bone Morphogenetic Protein ◽

Bone Morphogenetic Protein 2 ◽

Morphogenetic Protein ◽

Marrow Mesenchymal Stem Cells ◽

Rabbit Bone