Determination of the Complete Amino Acid Sequence of Recombinant Human γ-Interferon Produced in Escherichia coli

1986 ◽  
Vol 6 (4) ◽  
pp. 331-336 ◽  
Author(s):  
SHOJIRO YAMAZAKI ◽  
TSUNEO SHIMAZU ◽  
SHIGENOBU KIMURA ◽  
HIROHIKO SHIMIZU
Keyword(s):  
Escherichia Coli ◽  
Amino Acid ◽  
Amino Acid Sequence ◽  
Complete Amino Acid Sequence ◽  
Γ Interferon

Determination of the Complete Amino Acid Sequence of Protein S21 from Escherichia coli Ribosomes

1975 ◽  
Vol 356 (2) ◽  
pp. 1955-1976 ◽  
Author(s):  
Joël Vandekerckhove ◽  
Wilfried Rombauts ◽  
Ben Peeters ◽  
Brigitte Wittmann-Liebold
Keyword(s):  
Escherichia Coli ◽  
Amino Acid ◽  
Amino Acid Sequence ◽  
Complete Amino Acid Sequence

scholarly journals DETERMINATION OF THE COMPLETE AMINO-ACID SEQUENCE OF PORCINE MINIPLASMINOGEN

1985 ◽  
Vol 149 (2) ◽  
pp. 283-285
Author(s):  
Thomas Marti ◽  
Johann Schaller ◽  
Egon E. Rickli
Keyword(s):  
Amino Acid ◽  
Amino Acid Sequence ◽  
Complete Amino Acid Sequence

scholarly journals DETERMINATION OF THE COMPLETE AMINO ACID SEQUENCE OF CALMODULIN (PHENYLALANINE-RICH ACIDIC PROTEIN II) FROM BOVINE BRAIN

1980 ◽  
Vol 1 (3) ◽  
pp. 248-264 ◽  
Author(s):  
HISATAKA KASAI ◽  
YUKIO KATO ◽  
TOSHIAKI ISOBE ◽  
HIROSHI KAWASAKI ◽  
TSUNEO OKUYAMA
Keyword(s):  
Amino Acid ◽  
Amino Acid Sequence ◽  
Acidic Protein ◽  
Complete Amino Acid Sequence

scholarly journals Human heart cytochrome c oxidase subunit VIII Purification and determination of the complete amino acid sequence

FEBS Letters ◽  
1988 ◽  
Vol 240 (1-2) ◽  
pp. 127-132 ◽  
Author(s):  
André B.P. Van Kuilenburg ◽  
Anton O. Muijsers ◽  
Hans Demol ◽  
Henk L. Dekker ◽  
Jozef J. Van Beeumen
Keyword(s):  
Amino Acid ◽  
Cytochrome C ◽  
Amino Acid Sequence ◽  
Cytochrome C Oxidase ◽  
Human Heart ◽  
Complete Amino Acid Sequence ◽  
Oxidase Subunit

scholarly journals Phenotypic, Biochemical, and Genetic Analysis of KPC-41, a KPC-3 Variant Conferring Resistance to Ceftazidime-Avibactam and Exhibiting Reduced Carbapenemase Activity

2019 ◽  
Vol 63 (12) ◽  
Author(s):  
Linda Mueller ◽  
Amandine Masseron ◽  
Guy Prod’Hom ◽  
Tatiana Galperine ◽  
Gilbert Greub ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Amino Acids ◽  
Amino Acid ◽  
Klebsiella Pneumoniae ◽  
Genetic Analysis ◽  
Amino Acid Sequence ◽  
Cloning And Expression ◽  
Content Type ◽  
Amino Acid Insertion

ABSTRACT A novel KPC variant, KPC-41, was identified in a Klebsiella pneumoniae clinical isolate from Switzerland. This β-lactamase possessed a 3-amino-acid insertion (Pro-Asn-Lys) located between amino acids 269 and 270 compared to the KPC-3 amino acid sequence. Cloning and expression of the blaKPC-41 gene in Escherichia coli, followed by determination of MIC values and kinetic parameters, showed that KPC-41, compared to those of KPC-3, has an increased affinity to ceftazidime and a decreased sensitivity to avibactam, leading to resistance to ceftazidime-avibactam once produced in K. pneumoniae. Furthermore, KPC-41 exhibited a drastic decrease of its carbapenemase activity. This report highlights that a diversity of KPC variants conferring resistance to ceftazidime-avibactam already circulate in Europe.

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