hWJECM-Derived Oriented Scaffolds with Autologous Chondrocytes for Rabbit Cartilage Defect Repairing

2018 ◽  
Vol 24 (11-12) ◽  
pp. 905-914 ◽  
Author(s):  
Peng Zhao ◽  
Shuyun Liu ◽  
Yuhe Bai ◽  
Shibi Lu ◽  
Jiang Peng ◽  
...  
Keyword(s):  
Cartilage Defect ◽  
Rabbit Cartilage

scholarly journals Matrigel scaffold combined with Ad-hBMP7-transfected chondrocytes improves the repair of rabbit cartilage defect

2016 ◽  
Vol 13 (2) ◽  
pp. 542-550 ◽  
Author(s):  
Xiaopeng Xia ◽  
Jing Li ◽  
Bo Xia ◽  
Huilin Yang ◽  
Dongmei Zhang ◽  
...  
Keyword(s):  
Cartilage Defect ◽  
Rabbit Cartilage

Combined Effects of Bone Marrow-Derived Mesenchymal Stem Cells and PLGA-PEG-PLGA Scaffolds on Repair of Articular Cartilage Defect

2013 ◽  
Vol 815 ◽  
pp. 345-349 ◽  
Author(s):  
Ching Wen Hsu ◽  
Ping Liu ◽  
Song Song Zhu ◽  
Feng Deng ◽  
Bi Zhang
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Articular Cartilage ◽  
Growth Factor ◽  
Cartilage Defect ◽  
Cartilage Regeneration ◽  
Tissue Growth ◽  
Cartilage Defects

Here we reported a combined technique for articular cartilage repair, consisting of bone arrow mesenchymal stem cells (BMMSCs) and poly (dl-lactide-co-glycolide-b-ethylene glycol-b-dl-lactide-co-glycolide) (PLGA-PEG-PLGA) triblock copolymers carried with tissue growth factor (TGF-belat1). In the present study, BMMSCs seeded on PLGA-PEG-PLGA with were incubated in vitro, carried or not TGF-belta1, Then the effects of the composite on repair of cartilage defect were evaluated in rabbit knee joints in vivo. Full-thickness cartilage defects (diameter: 5 mm; depth: 3 mm) in the patellar groove were either left empty (n=18), implanted with BMMSCs/PLGA (n=18), TGF-belta1 modified BMMSCs/PLGA-PEG-PLGA. The defect area was examined grossly, histologically at 6, 24 weeks postoperatively. After implantation, the BMMSCs /PLGA-PEG-PLGA with TGF-belta1 group showed successful hyaline-like cartilage regeneration similar to normal cartilage, which was superior to the other groups using gross examination, qualitative and quantitative histology. These findings suggested that a combination of BMMSCs/PLGA-PEG-PLGA carried with tissue growth factor (TGF-belat1) may be an alternative treatment for large osteochondral defects in high loading sites.

Platelet-rich plasma inhibits Wnt/β-catenin signaling in rabbit cartilage cells activated by IL-1β

2018 ◽  
Vol 55 ◽  
pp. 282-289 ◽  
Author(s):  
Jian Wu ◽  
Ji-Feng Huang ◽  
Xing-Xing Qin ◽  
Feng Hu ◽  
Zhao-Fei Chen ◽  
...  
Keyword(s):  
Platelet Rich Plasma ◽  
Cartilage Cells ◽  
Rabbit Cartilage

Repair of a post-traumatic cartilage defect with a cell-free polymer-based cartilage implant

2010 ◽  
Vol 92-B (8) ◽  
pp. 1160-1163 ◽  
Author(s):  
J. M. Patrascu ◽  
U. Freymann ◽  
C. Kaps ◽  
D. V. Poenaru
Keyword(s):  
Cartilage Defect ◽  
A Cell ◽  
Post Traumatic

Gene expression profile of rabbit cartilage by expressed sequence tag analysis

Gene ◽  
2008 ◽  
Vol 424 (1-2) ◽  
pp. 147-152 ◽  
Author(s):  
Hyuck Joon Kwon ◽  
Hidetoshi Akimoto ◽  
Yoshihiro Ohmiya ◽  
Kenichi Honma ◽  
Kazunori Yasuda
Keyword(s):  
Gene Expression ◽  
Gene Expression Profile ◽  
Expression Profile ◽  
Expressed Sequence Tag ◽  
Rabbit Cartilage ◽  
Expressed Sequence Tag Analysis ◽  
Expressed Sequence

scholarly journals Hepatocyte growth factor facilitates cartilage repair: Full thickness articular cartilage defect studied in rabbit knees

1997 ◽  
Vol 68 (5) ◽  
pp. 474-480 ◽  
Author(s):  
Shigeyuki Wakitani ◽  
Kazuhiko Imoto ◽  
Tomoatsu Kimura ◽  
Takahiro Ochi ◽  
Kunio Matsumoto ◽  
...  
Keyword(s):  
Articular Cartilage ◽  
Growth Factor ◽  
Hepatocyte Growth Factor ◽  
Cartilage Repair ◽  
Cartilage Defect ◽  
Full Thickness ◽  
Articular Cartilage Defect ◽  
Hepatocyte Growth

Knee Cartilage Defect Documentation: Computer Assistance in Quantification of Cartilage Defects

Orthopedics ◽  
2005 ◽  
Vol 28 (10) ◽  
Author(s):  
Roberto Diaz ◽  
Matthew Kidwell ◽  
John Albright ◽  
Lori Dolan
Keyword(s):  
Cartilage Defect ◽  
Cartilage Defects ◽  
Knee Cartilage ◽  
Computer Assistance
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