Phase II, two-stage, single-arm trial of the histone deacetylase inhibitor (HDACi) romidepsin in metastatic castration-resistant prostate cancer (CRPC)

Annals of Oncology ◽

10.1093/annonc/mdp270 ◽

2010 ◽

Vol 21 (1) ◽

pp. 109-113 ◽

Author(s):

L.R. Molife ◽

G. Attard ◽

P.C. Fong ◽

V. Karavasilis ◽

A.H.M. Reid ◽

...

Keyword(s):

Prostate Cancer ◽

Histone Deacetylase ◽

Phase Ii ◽

Histone Deacetylase Inhibitor ◽

Castration Resistant Prostate Cancer ◽

Two Stage ◽

Castration Resistant ◽

Deacetylase Inhibitor

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Imaging assisted evaluation of antitumor efficacy of a new histone deacetylase inhibitor in the castration-resistant prostate cancer

European Journal of Nuclear Medicine and Molecular Imaging ◽

10.1007/s00259-020-04896-7 ◽

2020 ◽

Author(s):

Zude Chen ◽

Xiashuang Wang ◽

Xiaoshuang Yang ◽

Yulong Xu ◽

Yu Yang ◽

...

Keyword(s):

Prostate Cancer ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Antitumor Efficacy ◽

Castration Resistant Prostate Cancer ◽

Castration Resistant ◽

Deacetylase Inhibitor

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147: Low Concentration of a Histone Deacetylase Inhibitor, Depsipeptide (FK228), Enhances the Effect of Gemcitabine and Docetaxel in Hormone Refractory Prostate Cancer Cells

The Journal of Urology ◽

10.1016/s0022-5347(18)30412-9 ◽

2007 ◽

Vol 177 (4S) ◽

pp. 50-51

Author(s):

Masatoshi Kanzaki ◽

Hideaki Kakinuma ◽

Teruaki Kumazawa ◽

Takamitsu Inoue ◽

Mitsuru Saito ◽

...

Keyword(s):

Prostate Cancer ◽

Cancer Cells ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Hormone Refractory Prostate Cancer ◽

Prostate Cancer Cells ◽

Low Concentration ◽

Deacetylase Inhibitor ◽

Hormone Refractory

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Faculty Opinions recommendation of A phase II study of paclitaxel poliglumex in combination with transdermal estradiol for the treatment of metastatic castration-resistant prostate cancer after docetaxel chemotherapy.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.3350956.3039058 ◽

2010 ◽

Author(s):

Yoshihiko Hirao ◽

Kiyohide Fujimoto

Keyword(s):

Prostate Cancer ◽

Phase Ii ◽

Phase Ii Study ◽

Castration Resistant Prostate Cancer ◽

Castration Resistant ◽

Transdermal Estradiol ◽

Docetaxel Chemotherapy

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Prostate Cancer Prevention by Sulforaphane, a Novel Dietary Histone Deacetylase Inhibitor

10.21236/ada481322 ◽

2008 ◽

Author(s):

Yu Zhen

Keyword(s):

Prostate Cancer ◽

Cancer Prevention ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Prostate Cancer Prevention ◽

Deacetylase Inhibitor

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Histone Deacetylase Inhibitor Potentiates Anticancer Effect of Docetaxel via Modulation of Bcl-2 Family Proteins and Tubulin in Hormone Refractory Prostate Cancer Cells

The Journal of Urology ◽

10.1016/j.juro.2010.07.035 ◽

2010 ◽

Vol 184 (6) ◽

pp. 2557-2564 ◽

Author(s):

Jung Jin Hwang ◽

Yong Sook Kim ◽

Mi Joung Kim ◽

Dong Eun Kim ◽

In Gab Jeong ◽

...

Keyword(s):

Prostate Cancer ◽

Cancer Cells ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Hormone Refractory Prostate Cancer ◽

Prostate Cancer Cells ◽

Anticancer Effect ◽

Deacetylase Inhibitor ◽

Hormone Refractory

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Targeted MET Inhibition in Castration-Resistant Prostate Cancer: A Randomized Phase II Study and Biomarker Analysis with Rilotumumab plus Mitoxantrone and Prednisone

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-12-2605 ◽

2012 ◽

Vol 19 (1) ◽

pp. 215-224 ◽

Author(s):

Charles J. Ryan ◽

Mark Rosenthal ◽

Siobhan Ng ◽

Joshi Alumkal ◽

Joel Picus ◽

...

Keyword(s):

Prostate Cancer ◽

Phase Ii ◽

Phase Ii Study ◽

Castration Resistant Prostate Cancer ◽

Castration Resistant ◽

Randomized Phase Ii ◽

Biomarker Analysis

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MP87-11 INTERIM ANALYSIS OF AN OPEN LABEL PHASE II STUDY OF ENZALUTAMIDE AND RADIUM RA 233 DICHLORIDE IN SYMPTOMATIC, METASTATIC CASTRATION-RESISTANT PROSTATE CANCER PATIENTS.

The Journal of Urology ◽

10.1016/j.juro.2018.02.2911 ◽

2018 ◽

Vol 199 (4S) ◽

Author(s):

Neal Shore ◽

Paul Schellhammer ◽

Ronald Tutrone ◽

Neil Mariados ◽

Stacey Harrelson

Keyword(s):

Prostate Cancer ◽

Cancer Patients ◽

Phase Ii ◽

Interim Analysis ◽

Phase Ii Study ◽

Castration Resistant Prostate Cancer ◽

Castration Resistant ◽

Open Label Phase

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TALAPRO-1: An open-label, response rate phase II study of talazoparib (TALA) in men with DNA damage repair defects (DDR) and metastatic castration-resistant prostate cancer (mCRPC) who previously received taxane-based chemotherapy (CT) and progressed on ≥ 1 novel hormonal therapy (NHT)

Annals of Oncology ◽

10.1093/annonc/mdy284.068 ◽

2018 ◽

Vol 29 ◽

pp. viii301

Author(s):

J.S. de Bono ◽

C. Higano ◽

F. Saad ◽

K. Miller ◽

M. Casey ◽

...

Keyword(s):

Prostate Cancer ◽

Phase Ii ◽

Hormonal Therapy ◽

Response Rate ◽

Phase Ii Study ◽

Castration Resistant Prostate Cancer ◽

Castration Resistant ◽

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Glutathione-S-transferase pi 1(GSTP1) gene silencing in prostate cancer cells is reversed by the histone deacetylase inhibitor depsipeptide

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2011.08.007 ◽

2011 ◽

Vol 412 (4) ◽

pp. 606-611 ◽

Author(s):

Vera Hauptstock ◽

Sapuna Kuriakose ◽

Doris Schmidt ◽

Robert Düster ◽

Stefan C. Müller ◽

...

Keyword(s):

Prostate Cancer ◽

Gene Silencing ◽

Cancer Cells ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Prostate Cancer Cells ◽

Glutathione S Transferase ◽

Deacetylase Inhibitor ◽

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A randomized phase II clinical trial of personalized peptide vaccination with metronomic low-dose cyclophosphamide in patients with metastatic castration-resistant prostate cancer

Cancer Immunology Immunotherapy ◽

10.1007/s00262-015-1781-6 ◽

2016 ◽

Vol 65 (2) ◽

pp. 151-160 ◽

Author(s):

Masanori Noguchi ◽

Fukuko Moriya ◽

Noriko Koga ◽

Satoko Matsueda ◽

Tetsuro Sasada ◽

...

Keyword(s):

Prostate Cancer ◽

Clinical Trial ◽

Phase Ii ◽

Low Dose ◽

Phase Ii Clinical Trial ◽

Castration Resistant Prostate Cancer ◽

Peptide Vaccination ◽

Castration Resistant ◽

Randomized Phase Ii

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