Rapid LC--ESI-MS--MS Method for the Simultaneous Determination of Clopidogrel and its Carboxylic Acid Metabolite in Human Plasma

Journal of Chromatographic Science ◽

10.1093/chromsci/46.10.867 ◽

2008 ◽

Vol 46 (10) ◽

pp. 867-875 ◽

Author(s):

N. K. Patel ◽

G. Subbaiah ◽

H. Shah ◽

M. Mohan ◽

P. S. Shrivastav

Keyword(s):

Carboxylic Acid ◽

Simultaneous Determination ◽

Human Plasma ◽

Acid Metabolite ◽

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Simultaneous Determination of Clopidogrel and Its Carboxylic Acid Metabolite (SR26334) in Human Plasma by LC–ESI–MS–MS: Application to the Therapeutic Drug Monitoring of Clopidogrel

Chromatographia ◽

10.1365/s10337-009-1349-8 ◽

2009 ◽

Vol 70 (11-12) ◽

pp. 1581-1586 ◽

Author(s):

Jian-Jun Zou ◽

Hong-Wei Fan ◽

Da-Qing Guo ◽

Ying-Bin Li ◽

Song Lin ◽

...

Keyword(s):

Carboxylic Acid ◽

Therapeutic Drug Monitoring ◽

Simultaneous Determination ◽

Human Plasma ◽

Drug Monitoring ◽

Therapeutic Drug ◽

Acid Metabolite ◽

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Development and Validation of an Improved LC Method for the Simultaneous Determination of Pirfenidone and Its Carboxylic Acid Metabolite in Human Plasma

Chromatographia ◽

10.1365/s10337-008-0910-1 ◽

2008 ◽

Vol 69 (5-6) ◽

pp. 459-463 ◽

Author(s):

Shaojun Shi ◽

Jianhong Wu ◽

Jun Wu ◽

Fandian Zeng

Keyword(s):

Carboxylic Acid ◽

Simultaneous Determination ◽

Human Plasma ◽

Acid Metabolite ◽

Development And Validation

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High-performance liquid chromatographic separation and extraction investigation for the simultaneous determination of mefloquine and its carboxylic acid metabolite

Journal of Chromatography B Biomedical Sciences and Applications ◽

10.1016/0378-4347(88)80132-4 ◽

1988 ◽

Vol 427 ◽

pp. 295-305 ◽

Author(s):

Yngve Bergqvist ◽

Solveig Eckerbom ◽

Niklas Larsson ◽

Frederick C. Churchill

Keyword(s):

Carboxylic Acid ◽

Simultaneous Determination ◽

Chromatographic Separation ◽

High Performance ◽

High Performance Liquid Chromatographic ◽

Acid Metabolite ◽

Liquid Chromatographic Separation ◽

Liquid Chromatographic

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Simultaneous Determination of Seven Components in Human Plasma by LC–ESI–MS/MS After Oral Administration of Danqi Tablets with Application to a Pharmacokinetic Study

Chromatographia ◽

10.1007/s10337-017-3365-4 ◽

2017 ◽

Vol 80 (9) ◽

pp. 1361-1369 ◽

Author(s):

Jiawei Shen ◽

Xiuqin Cao

Keyword(s):

Oral Administration ◽

Simultaneous Determination ◽

Human Plasma ◽

Pharmacokinetic Study ◽

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Capillary Zone Electrophoresis method for determination of (+)-S clopidogrel carboxylic acid metabolite in human plasma and urine designed for biopharmaceutic studies

Journal of Chromatography B ◽

10.1016/j.jchromb.2010.02.033 ◽

2010 ◽

Vol 878 (13-14) ◽

pp. 1013-1018 ◽

Author(s):

Marta Karaźniewicz-Łada ◽

Franciszek Główka ◽

Grzegorz Oszkinis

Keyword(s):

Carboxylic Acid ◽

Human Plasma ◽

Capillary Zone Electrophoresis ◽

Acid Metabolite ◽

Human Plasma And Urine ◽

Zone Electrophoresis ◽

Electrophoresis Method ◽

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Simultaneous determination of cyclophosphamide and carboxyethylphosphoramide mustard in human plasma using online extraction and electrospray tandem mass spectrometry (HTLC–ESI-MS/MS)

Journal of Chromatography B ◽

10.1016/j.jchromb.2009.04.025 ◽

2009 ◽

Vol 877 (18-19) ◽

pp. 1709-1715 ◽

Author(s):

Feng Bai ◽

Charles H. Fraga ◽

Michael Tagen ◽

Paula Schaiquevich ◽

Nikolaus Hagedorn ◽

...

Keyword(s):

Mass Spectrometry ◽

Tandem Mass Spectrometry ◽

Simultaneous Determination ◽

Human Plasma ◽

Tandem Mass ◽

Electrospray Tandem Mass Spectrometry ◽

Esi Ms ◽

Online Extraction

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Validation and clinical application of an LC-ESI-MS/MS method for simultaneous determination of tolmetin and MED5, the metabolites of amtolmetin guacil in human plasma

Biomedical Chromatography ◽

10.1002/bmc.1411 ◽

2010 ◽

Vol 24 (10) ◽

pp. 1100-1107 ◽

Author(s):

Kishore Kumar Hotha ◽

D. Vijaya Bharathi ◽

S. Sirish Kumar ◽

Y. Narsimha Reddy ◽

Pankaj Chatki ◽

...

Keyword(s):

Simultaneous Determination ◽

Human Plasma ◽

Clinical Application ◽

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HPLC–MS/MS method for the simultaneous determination of clopidogrel, its carboxylic acid metabolite and derivatized isomers of thiol metabolite in clinical samples

Journal of Chromatography B ◽

10.1016/j.jchromb.2012.11.005 ◽

2012 ◽

Vol 911 ◽

pp. 105-112 ◽

Author(s):

Marta Karaźniewicz-Łada ◽

Dorota Danielak ◽

Artur Teżyk ◽

Czesław Żaba ◽

Gilles Tuffal ◽

...

Keyword(s):

Carboxylic Acid ◽

Simultaneous Determination ◽

Clinical Samples ◽

Acid Metabolite

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Simultaneous determination of fourteen components of Gumiganghwal-tang tablet in human plasma by UPLC-ESI-MS/MS and its application to pharmacokinetic study

Journal of Pharmaceutical Analysis ◽

10.1016/j.jpha.2020.08.003 ◽

2020 ◽

Author(s):

Seung-Hyun Jeong ◽

Ji-Hun Jang ◽

Guk-Yeo Lee ◽

Seung-Jung Yang ◽

Hea-Young Cho ◽

...

Keyword(s):

Simultaneous Determination ◽

Human Plasma ◽

Pharmacokinetic Study ◽

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A quantitative LC-MS/MS method for simultaneous determination of deuvortioxetine, vortioxetine and their carboxylic acid metabolite in rat plasma, and its application to a toxicokinetic study

Analytical Methods ◽

10.1039/c7ay02642k ◽

2018 ◽

Vol 10 (9) ◽

pp. 1023-1031 ◽

Author(s):

Mei Qin ◽

Hong-qun Qiao ◽

Yan-juan Yuan ◽

Qing Shao

Keyword(s):

Carboxylic Acid ◽

Simultaneous Determination ◽

Stable Method ◽

Acid Metabolite

A rapid, simple, efficient and stable method based on LC-MS/MS for simultaneous determination of deuvortioxetine, vortioxetine and their carboxylic acid metabolite in rat plasma has been established and validated.

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