Rapid Gas-Chromatographic Determination of Amphetamine and Methamphetamine in Urine
1974 ◽
Vol 20
(11)
◽
pp. 1460-1462
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Keyword(s):
Abstract A simple, rapid procedure is described for measuring amphetamine and methamphetamine in urine by gas chromatography, with use of a flame ionization detector. This method is sensitive to subtherapeutic concentrations (0.1 µg/ml or less), and is especially useful in clinical situations where an accurate and quantitative result is needed in less than 30 min. With the method, amphetamine and methamphetamine can be determined as the free bases on a 10% Apiezon L-10% KOH column and as their trifluoroacetamide derivatives on a 3% OV-17 column. This dual analysis eliminates false positives and any interfering substances that may be present in the urine, and is thus a specific method for the two drugs.
1977 ◽
Vol 135
(1)
◽
pp. 141-148
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1981 ◽
Vol 64
(5)
◽
pp. 1122-1130
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1980 ◽
Vol 197
(2)
◽
pp. 263-266
◽
1993 ◽
Vol 642
(1-2)
◽
pp. 383-388
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