scholarly journals 169-07: Long term changes in transmural dispersion of repolarisation in patients with heart failure after cardiac resynchronisation therapy- A prospective study

EP Europace ◽  
2016 ◽  
Vol 18 (suppl_1) ◽  
pp. i116-i116
Author(s):  
Bharatraj Banavalikar ◽  
V.k. Ajit Kumar ◽  
Anees Thajudeen ◽  
Narayanan Namboodiri ◽  
Krishna Kumar Nair ◽  
...  
2016 ◽  
Vol 23 (4) ◽  
pp. 470-475
Author(s):  
Francesco MA Brasca ◽  
Jessica Franzetti ◽  
Valeria Rella ◽  
Gabriella Malfatto ◽  
Roberto Brambilla ◽  
...  

Aim The Program to Access and Review Trending iNformation and Evaluate coRrelation to Symptoms in patients with Heart Failure (PARTNERS HF) trial elaborated a multiparametric model for prediction of acute decompensation in advanced heart failure patients, based on periodical in office data download from cardiac resynchronisation devices. In this study, we evaluated the ability of the PARTNERS HF criteria to detect initial decompensation in a population of moderate heart failure patients under remote monitoring. Methods We retrospectively applied the PARTNERS HF criteria to 1860 transmissions from 104 patients (median follow up 21 months; range 1–67 months), who were enrolled in our programme of telemedicine after cardiac resynchronisation therapy. We tested the ability of a score based on these criteria to predict any acute clinical decompensation occurring in the 15 days following a transmission. Results In 441 cases, acute heart failure was diagnosed after the index transmission. The area under the curve (AUC) of the score for the diagnosis of acute decompensation was 0.752 (confidence interval (CI) 95% 0.728–0.777). The best score cut-off was consistent with the results of PARTNERS HF: with a score ≥2, sensitivity was 75% and specificity 68%. The odds ratio for events was 6.24 (CI 95% 4.90–7.95; p < 0.001). Conclusions When retrospectively applied to remote monitoring transmissions and arranged in a score, PARTNERS HF criteria could identify HF patients who subsequently developed acute decompensation. These results warrant prospective studies applying PARTNERS HF criteria to remote monitoring.


Heart ◽  
2010 ◽  
Vol 96 (14) ◽  
pp. 1107-1113 ◽  
Author(s):  
R. J. van Bommel ◽  
J. Gorcsan ◽  
E. S. Chung ◽  
W. T. Abraham ◽  
F. T. Gjestvang ◽  
...  

2015 ◽  
Vol 1 (1) ◽  
pp. 35 ◽  
Author(s):  
Fang Fang ◽  
Zhou Yu Jie ◽  
Luo Xiu Xia ◽  
Liu Ming ◽  
Ma Zhan ◽  
...  

Chronic heart failure is still a major challenge for healthcare. Currently, cardiac resynchronisation therapy (CRT) has been incorporated into the updated guideline for patients with heart failure, left ventricular ejection fraction ≤35 % and prolonged QRS duration. With 20 years of development, the concept of ‘from bench to bedside’ has been illustrated in the field of CRT. Given the fact that the indications of CRT keep evolving, the role of CRT is not limited to the curative method for heart failure. We therefore summarise with the perspective of 5P medicine – preventive, personalised, predictive, participatory, promotive, to review the benefit of CRT in the prevention of heart failure in those with conventional pacemaker indications, the individualised assessment of patient’s selection, the predictor of responders of CRT, and the obstacles hindering the more application of CRT and the future development of this device therapy.


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