scholarly journals MULTIMORBIDITY IN OLDER ADULTS: CAN DISEASE CLUSTER PREDICT DEPRESSION SEVERITY?

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S393-S394
Author(s):  
Jacquelyn Minahan
Keyword(s):  
Older Adults ◽  
Depressive Symptom ◽  
Symptom Severity ◽  
Social Life ◽  
Chronic Conditions ◽  
Secondary Data ◽  
Depression Severity ◽  
Disease Clusters ◽  
Disease Cluster ◽  
Depressive Symptom Severity

Abstract Multimorbidity, defined as the co-occurrence of two or more chronic conditions, is positively correlated with depression severity among older adults. However, few studies have compared depression outcomes by disease cluster. To address this gap, secondary data analyses were performed using data from the National Social Life, Health, and Aging Project (NSHAP), Wave 2. For the purpose of this study, disease clusters are composed of conditions that implicate similar body systems (e.g., musculoskeletal system, cardiovascular system). Participants reported an average of 2.69 (+/- 1.97) chronic conditions. Multimorbidity and depressive symptom severity, as measured by the Center for Epidemiological Studies – Depression, Iowa Form (CES-D) were positively associated (p<0.001). Individual disease clusters, age, self-identifying as female, and lower educational attainment were predictive of depressive symptom severity (p<0.001). Findings support the necessary inclusion of social determinants (health status, gender, education, age) in the conceptualization of health and health outcomes within an aging population.

scholarly journals Depressive symptom severity is associated with increased cortical thickness in older adults

2015 ◽  
Vol 31 (4) ◽  
pp. 325-333 ◽  
Author(s):  
Sarah M. Szymkowicz ◽  
Molly E. McLaren ◽  
Joshua W. Kirton ◽  
Andrew O'Shea ◽  
Adam J. Woods ◽  
...  
Keyword(s):  
Older Adults ◽  
Depressive Symptom ◽  
Cortical Thickness ◽  
Symptom Severity ◽  
Depressive Symptom Severity

scholarly journals CAREGIVER DEPRESSIVE SYMPTOM SEVERITY AMONG OLDER ADULTS WITH COGNITIVE VULNERABILITY

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S385-S386
Author(s):  
Richard H Fortinsky ◽  
Dorothy Wakefield
Keyword(s):  
Older Adults ◽  
Depressive Symptoms ◽  
Depressive Symptom ◽  
Symptom Severity ◽  
Cognitive Vulnerability ◽  
Family Members ◽  
Depression Scale ◽  
Cognitive Status ◽  
Cognitive Symptom ◽  
Depressive Symptom Severity

Abstract While caregivers of older adults with dementia often report considerable levels of depressive symptoms, much less is known about depressive symptoms among family members of older adults with depression or recent delirium. As part of an ongoing randomized clinical trial testing an in-home multidisciplinary team intervention for older adults with cognitive vulnerability due to dementia, depression, and/or delirium (care recipients, or CR) and their caregivers, in this presentation we report baseline data from the first 211 dyads enrolled in the trial to determine how caregiver depressive symptom severity is related to: CR diagnoses; CR cognitive impairment severity; and CR depressive symptom severity. CR diagnostic groups: Depression Only (n=49); Dementia Only (n=61); Depression and Dementia Only (n=47); Delirium Plus (n=54). Depressive symptom severity was measured using the Center for Epidemiologic Studies Depression Scale; CR cognitive symptom severity was measured using the Telephone Interview for Cognitive Status. Among CR, 57% were female, mean/sd age=77/6.9, 93% White; among caregivers, 64% were female, mean/sd age=66/13.7, 91% White, 55% spouses, 25% daughters, 9% sons. In multivariate linear regression models, which included covariates caregiver gender, relationship to CR, and number of hours/week providing care, we found that caregiver depressive symptom severity was less severe among caregivers of CR with Dementia Only compared to CR with Depression Only (b=-3.32; p=0.06); not associated with CR cognitive symptom severity; and significantly associated with CR depressive symptom severity (b=0.14; p<0.01). We conclude that family members of older adults with depression deserve greater attention to address their own depressive symptoms.

scholarly journals Depressive symptom severity and mortality in older adults undergoing percutaneous coronary intervention

2016 ◽  
Vol 221 ◽  
pp. 521-523 ◽  
Author(s):  
S. Michael Gharacholou ◽  
Veronique L. Roger ◽  
Ryan J. Lennon ◽  
Mark A. Frye ◽  
Charanjit S. Rihal ◽  
...  
Keyword(s):  
Older Adults ◽  
Percutaneous Coronary Intervention ◽  
Depressive Symptom ◽  
Symptom Severity ◽  
Coronary Intervention ◽  
Percutaneous Coronary ◽  
Depressive Symptom Severity

scholarly journals The contribution of depressive ‘disorder characteristics’ to determinations of prognosis for adults with depression: an individual patient data meta-analysis

2021 ◽  
pp. 1-14
Author(s):  
Joshua E. J. Buckman ◽  
Rob Saunders ◽  
Zachary D. Cohen ◽  
Phoebe Barnett ◽  
Katherine Clarke ◽  
...  
Keyword(s):  
Primary Care ◽  
Depressive Symptoms ◽  
Depressive Symptom ◽  
Panic Disorder ◽  
Symptom Severity ◽  
Individual Patient Data ◽  
Antidepressant Treatment ◽  
Patient Data ◽  
History Of ◽  
Depressive Symptom Severity

Abstract Background This study aimed to investigate general factors associated with prognosis regardless of the type of treatment received, for adults with depression in primary care. Methods We searched Medline, Embase, PsycINFO and Cochrane Central (inception to 12/01/2020) for RCTs that included the most commonly used comprehensive measure of depressive and anxiety disorder symptoms and diagnoses, in primary care depression RCTs (the Revised Clinical Interview Schedule: CIS-R). Two-stage random-effects meta-analyses were conducted. Results Twelve (n = 6024) of thirteen eligible studies (n = 6175) provided individual patient data. There was a 31% (95%CI: 25 to 37) difference in depressive symptoms at 3–4 months per standard deviation increase in baseline depressive symptoms. Four additional factors: the duration of anxiety; duration of depression; comorbid panic disorder; and a history of antidepressant treatment were also independently associated with poorer prognosis. There was evidence that the difference in prognosis when these factors were combined could be of clinical importance. Adding these variables improved the amount of variance explained in 3–4 month depressive symptoms from 16% using depressive symptom severity alone to 27%. Risk of bias (assessed with QUIPS) was low in all studies and quality (assessed with GRADE) was high. Sensitivity analyses did not alter our conclusions. Conclusions When adults seek treatment for depression clinicians should routinely assess for the duration of anxiety, duration of depression, comorbid panic disorder, and a history of antidepressant treatment alongside depressive symptom severity. This could provide clinicians and patients with useful and desired information to elucidate prognosis and aid the clinical management of depression.

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