scholarly journals ASSESSING DIMENSIONS OF EXECUTIVE FUNCTION IN COMMUNITY-DWELLING OLDER ADULTS WHO SELF-NEGLECT

2015 ◽  
Vol 55 (Suppl_2) ◽  
pp. 154-154
2018 ◽  
Vol 4 ◽  
pp. 233372141881149 ◽  
Author(s):  
Shunsuke Murata ◽  
Sho Nakakubo ◽  
Tsunenori Isa ◽  
Yamato Tsuboi ◽  
Kohtaroh Torizawa ◽  
...  

Author(s):  
Jen-Hau Chen ◽  
Tsung-Yu Kuo ◽  
Hwa-Lung Yu ◽  
Charlene Wu ◽  
Su-Ling Yeh ◽  
...  

Background: Previous studies have assessed limited cognitive domains with relatively short exposure to air pollutants, and studies in Asia are limited. Objective: This study aims to explore the association between long-term exposure to air pollutants and cognition in community-dwelling older adults. Methods: This four-year prospective cohort study recruited 605 older adults at baseline (2011–2013) and 360 participants remained at four-year follow-up. Global and domain-specific cognition were assessed biennially. Data on PM2.5 (particulate matter ≤ 2.5 μm diameter, 2005–2015), PM10 (1993–2015), and nitrogen dioxide (NO2, 1993–2015) were obtained from Taiwan Environmental Protection Administration (TEPA). Bayesian Maximum Entropy was utilized to estimate the spatiotemporal distribution of levels of these pollutants. Results: Exposure to high-level PM2.5 (>29.98 μg/m3) was associated with an increased risk of global cognitive impairment (adjusted odds ratio = 4.56; β = −0.60). High-level PMcoarse exposure (>26.50 μg/m3) was associated with poor verbal fluency (β = −0.19). High-level PM10 exposure (>51.20 μg/m3) was associated with poor executive function (β = −0.24). Medium-level NO2 exposure (>28.62 ppb) was associated with better verbal fluency (β = 0.12). Co-exposure to high concentrations of PM2.5, PMcoarse or PM10 and high concentration of NO2 were associated with poor verbal fluency (PM2.5 and NO2: β = −0.17; PMcoarse and NO2: β = −0.23; PM10 and NO2: β = −0.21) and poor executive function (PM10 and NO2: β = −0.16). These associations became more evident in women, apolipoprotein ε4 non-carriers, and those with education > 12 years. Conclusion: Long-term exposure to PM2.5 (higher than TEPA guidelines), PM10 (lower than TEPA guidelines) or co-exposure to PMx and NO2 were associated with poor global, verbal fluency, and executive function over 4 years.


2017 ◽  
Vol 1 (suppl_1) ◽  
pp. 1051-1051
Author(s):  
C. Smith ◽  
C. Bula ◽  
H. Krief ◽  
L. Seematter-Bagnoud ◽  
B. Santos-Eggimann

2020 ◽  
Vol 78 (4) ◽  
pp. 1585-1600
Author(s):  
Jen-Hau Chen ◽  
Tsung-Yu Kuo ◽  
Hwa-Lung Yu ◽  
Charlene Wu ◽  
Su-Ling Yeh ◽  
...  

Background: Previous studies have assessed limited cognitive domains with relatively short exposure to air pollutants, and studies in Asia are limited. Objective: This study aims to explore the association between long-term exposure to air pollutants and cognition in community-dwelling older adults. Methods: This four-year prospective cohort study recruited 605 older adults at baseline (2011–2013) and 360 participants remained at four-year follow-up. Global and domain-specific cognition were assessed biennially. Data on PM2.5 (particulate matter≤2.5μm diameter, 2005–2015), PM10 (1993–2015), and nitrogen dioxide (NO2, 1993–2015) were obtained from Taiwan Environmental Protection Administration (TEPA). Bayesian Maximum Entropy was utilized to estimate the spatiotemporal distribution of levels of these pollutants. Results: Exposure to high-level PM2.5 (>29.98μg/m3) was associated with an increased risk of global cognitive impairment (adjusted odds ratio = 4.56; β= –0.60). High-level PMcoarse exposure (>26.50μg/m3) was associated with poor verbal fluency (β= –0.19). High-level PM10 exposure (>51.20μg/m3) was associated with poor executive function (β= –0.24). Medium-level NO2 exposure (>28.62 ppb) was associated with better verbal fluency (β= 0.12). Co-exposure to high concentrations of PM2.5, PMcoarse or PM10 and high concentration of NO2 were associated with poor verbal fluency (PM2.5 and NO2: β= –0.17; PMcoarse and NO2: β= –0.23; PM10 and NO2: β= –0.21) and poor executive function (PM10 and NO2: β= –0.16). These associations became more evident in women, apolipoprotein ɛ4 non-carriers, and those with education > 12 years. Conclusion: Long-term exposure to PM2.5 (higher than TEPA guidelines), PM10 (lower than TEPA guidelines) or co-exposure to PMx and NO2 were associated with poor global, verbal fluency, and executive function over 4 years.


2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 700-700
Author(s):  
Jennifer Blackwood ◽  
Reza Amini ◽  
Gerry Conti ◽  
Quinn Hanses ◽  
Rebekah Taylor ◽  
...  

Abstract Declines in Executive Function (EF) are associated with balance in community-dwelling older adults with Mild Cognitive Impairment (MCI). While this has been examined in cross-sectional studies, no longitudinal studies describe change over time. The purpose of this study was to examine how performance on the components of the Short Physical Performance Battery (SPPB) are associated with EF in community-dwelling older adults who transition into MCI. This secondary data analysis employed eight years of data from the National Health and Aging Trends Study dataset (2011 – 2018) with 1,225 participants in all eight waves (balanced). EF was measured with the Clock Drawing Test and SPPB balance tests included side-by-side, semi-tandem, full tandem, and single leg stance with eyes open or closed. Longitudinal ordered logistic regression was used to examine associations between each balance measure and EF while controlling for comorbidity, function, depression, gender, age, and ethnicity. EF was significantly associated with tandem, semi-tandem, and single leg stance after controlling for covariates. One point increase in SPPB can reduce the risk of EF impairment by 8.2% (Odds Ratio (OR)=0.918, p<0.001). Among SPPB components, semi-tandem (OR=0.468) and side-by-side (OR=0.472) were the strongest predictors of EF impairment. Declines in both EF and balance performance occurred over an eight-year period in adults. This may reflect common neural processes shared between the cognitive and motor areas of the central nervous system. Best practice suggests screening both balance (tandem, semi-tandem, or single leg stance) and EF in the clinical assessment of community-dwelling older adults.


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