A polymorphic dinucleotide repeat in intron 1 of the human tissue plasminogen activator gene

1992 ◽  
Vol 1 (2) ◽  
pp. 138-138 ◽  
Author(s):  
W. Thomas ◽  
D. Drayna
Keyword(s):  
Plasminogen Activator ◽  
Tissue Plasminogen Activator ◽  
Human Tissue ◽  
Dinucleotide Repeat ◽  
Intron 1 ◽  
Polymorphic Dinucleotide Repeat ◽  
Tissue Plasminogen ◽  
Polymorphic Dinucleotide

Cloning and Expression of a Human Tissue Plasminogen Activator Variant:K2S in Escherichia coli

2007 ◽  
Vol 10 (6) ◽  
pp. 946-949 ◽  
Author(s):  
Hamid Mir Mohammad S ◽  
Kianoush Dormiani ◽  
Yahya Khazaie ◽  
Mohammad Rabbani ◽  
Fatemeh Moazen
Keyword(s):  
Escherichia Coli ◽  
Plasminogen Activator ◽  
Tissue Plasminogen Activator ◽  
Human Tissue ◽  
Cloning And Expression ◽  
Tissue Plasminogen

Inhibitors Interfering with the Quantitative Estimation of Tissue Plasminogen Activator

1975 ◽  
Author(s):  
G. Wijngaards ◽  
A. T. Potjer
Keyword(s):  
Plasminogen Activator ◽  
Tissue Plasminogen Activator ◽  
Human Tissue ◽  
Inhibitory Action ◽  
Human Lung ◽  
Quantitative Estimation ◽  
Plasminogen Activators ◽  
Tissue Extracts ◽  
Tissue Plasminogen ◽  
Inhibitory Components

The commonly used quantitative assay for plasminogen activator in tissues by Astrup and Albrechtsen (1957) was re-evaluated with special reference to the presence of inhibitors in tissue extracts at different stages of the procedure.Human lung, liver, and placenta tissues were chosen for their different activator and inhibitor content. Samples of the extracts were tested for inhibitory capacity against purified human tissue plasminogen activator, urokinase, and plasmin on different kinds of fibrin plates.The procedure for preparing the samples according to Astrup and Albrechtsen did not completely eliminate the inhibitory action against the plasminogen activators added. The presence of inhibitors was partly obscured by 2M KCNS in the sample. In order to quantitate the plasminogen activator content in tissues, the method should be revised with respect to the elimination of inhibiting material.Some interesting aspects of the inhibitory components extracted from liver and placenta were revealed by comparing urokinase inhibition to tissue activator inhibition as to the degree of denaturation during the procedure. It was suggested that, although they have much in common, urokinase and tissue activator inhibitors are separate entities.

Synthesis and Purification of Active Human Tissue Plasminogen Activator From Escherichia coli

1989 ◽  
Vol 7 (5) ◽  
pp. 495-501 ◽  
Author(s):  
Paolo Sarmientos ◽  
Marc Duchesne ◽  
Patrice Denèfle ◽  
Janine Boiziau ◽  
Nadine Fromage ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Plasminogen Activator ◽  
Tissue Plasminogen Activator ◽  
Human Tissue ◽  
Tissue Plasminogen

scholarly journals Isolation of cDNA sequences coding for a part of human tissue plasminogen activator.

1983 ◽  
Vol 80 (2) ◽  
pp. 349-352 ◽  
Author(s):  
T. Edlund ◽  
T. Ny ◽  
M. Ranby ◽  
L. O. Heden ◽  
G. Palm ◽  
...  
Keyword(s):  
Plasminogen Activator ◽  
Tissue Plasminogen Activator ◽  
Human Tissue ◽  
Cdna Sequences ◽  
Tissue Plasminogen

Cloning and Expression of Functional Full-Length Human Tissue Plasminogen Activator in Pichia pastoris

2010 ◽  
Vol 162 (7) ◽  
pp. 2037-2048 ◽  
Author(s):  
Keivan Majidzadeh-A ◽  
Vahid Khalaj ◽  
Davami Fatemeh ◽  
Hemayatkar Mahdi ◽  
Barkhordari Farzaneh ◽  
...  
Keyword(s):  
Pichia Pastoris ◽  
Plasminogen Activator ◽  
Tissue Plasminogen Activator ◽  
Human Tissue ◽  
Full Length ◽  
Cloning And Expression ◽  
Tissue Plasminogen
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