Characterization of Human Herpesvirus 6 Strains Isolated from Patients with Exanthem Subitum with or without Cutaneous Rash

1992 ◽  
Vol 166 (3) ◽  
pp. 689-689 ◽  
Author(s):  
D. Di Luca ◽  
P. Mirandola ◽  
P. Secchiero ◽  
C. Cermelli ◽  
A. Aleotti ◽  
...  
Keyword(s):  
Human Herpesvirus ◽  
Human Herpesvirus 6 ◽  
Exanthem Subitum ◽  
Cutaneous Rash ◽  
Herpesvirus 6

IDENTIFICATION OF HUMAN HERPESVIRUS-6 AS A CAUSAL AGENT FOR EXANTHEM SUBITUM

The Lancet ◽  
1988 ◽  
Vol 331 (8594) ◽  
pp. 1065-1067 ◽  
Author(s):  
Koichi Yamanishi ◽  
Kimiyasu Shiraki ◽  
Toshio Kondo ◽  
Toshiomi Okuno ◽  
Michiaki Takahashi ◽  
...  
Keyword(s):  
Human Herpesvirus ◽  
Causal Agent ◽  
Human Herpesvirus 6 ◽  
Exanthem Subitum ◽  
Herpesvirus 6

Selection and characterization of two specific monoclonal antibodies directed against the two variants of human herpesvirus-6

1998 ◽  
Vol 149 (6) ◽  
pp. 403-411 ◽  
Author(s):  
C. Robert ◽  
V. Massonneau ◽  
P. Pothier ◽  
A. Clément ◽  
G. Hejblum ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Human Herpesvirus ◽  
Human Herpesvirus 6 ◽  
Herpesvirus 6

Utilization of human hematopoietic cell lines for the propagation and characterization of HBLV (human herpesvirus 6)

1988 ◽  
Vol 42 (5) ◽  
pp. 787-791 ◽  
Author(s):  
Dharam V. Ablashi ◽  
Paolo Lusso ◽  
Chia-Ling Hung ◽  
S. Zaki Salahuddin ◽  
Steven F. Josephs ◽  
...  
Keyword(s):  
Cell Lines ◽  
Human Herpesvirus ◽  
Hematopoietic Cell ◽  
Human Herpesvirus 6 ◽  
Herpesvirus 6 ◽  
Hematopoietic Cell Lines

scholarly journals Association of human herpesvirus 6 infection with exanthem subitum in Belem, Brazil

1995 ◽  
Vol 37 (6) ◽  
pp. 489-492 ◽  
Author(s):  
R. B. de Freitas ◽  
A. C. Linhares ◽  
C. S. Oliveira ◽  
R. H. P. Gusmão ◽  
M. I. S. Linhares
Keyword(s):  
Lymph Node ◽  
Cervical Lymph Node ◽  
Human Herpesvirus ◽  
Human Herpesvirus 6 ◽  
Antibody Assay ◽  
Serum Samples ◽  
Exanthem Subitum ◽  
Lymph Node Swelling ◽  
Herpesvirus 6 ◽  
Immunofluorescence Antibody

Recent human herpesvirus 6 (HHV-6) infection was detected in cases of exanthem subitum (ES) involving four children, aged 10 to 24 months, between April and August 1994, in Belém, Brazil. By using the indirect immunofluorescence antibody assay (IFA), significant increases (at least eight times) in antibody concentrations were noted from the acute to the convalescent serum samples, with titers ranging from <1:10/1:80 to <1:10/1:640 (patients 3 and 2, respectively). All children had high fever (over 39ºC) for three days, followed by generalized, maculo-papular skin rash. A physical examination of the children also revealed concomitant, cervical lymph node swelling and tonsillar pharyngitis in two of them.

Distribution of Antibodies to a Causative Agent of Exanthem Subitum (Human Herpesvirus-6) in Healthy Individuals

PEDIATRICS ◽  
1989 ◽  
Vol 84 (4) ◽  
pp. 675-677
Author(s):  
Tetsushi Yoshikawa ◽  
Sadao Suga ◽  
Yoshizo Asano ◽  
Takehiko Yazaki ◽  
Hiroshi Kodama ◽  
...  
Keyword(s):  
Cord Blood ◽  
Causative Agent ◽  
Human Herpesvirus ◽  
Immunofluorescence Assay ◽  
Healthy Individuals ◽  
Human Herpesvirus 6 ◽  
Exanthem Subitum ◽  
Adolescents And Adults ◽  
Positive Rate ◽  
Herpesvirus 6

The transfer of IgG antibodies to a causative agent of exanthem subitum (human herpesvirus-6) from mother to infant was examined with an indirect immunofluorescence assay. Of 20 mothers, 85% had the antibody more than 1:10, and the significantly higher level of the antibody was found in the cord blood with a positive rate of 95%. A mean ratio of cord blood to maternal antibody titer was 1.63. A total of 301 sera from healthy individuals was examined for the age-specific prevalence of antibody to the virus. In the first 2 months of life, 87% of infants had the antibody; the positive rate and the level of antibody decreased during the first 6 months of life with the lowest positive rate of 6% at 4 to 5 months of age. After 6 months of age, they increased gradually and reached the highest level at 1 year of age with the positive rate of 86%. From 2 years of age, the prevalence of the antibody was almost stable (69% to 76%) and similar to those in adolescents and adults.

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