A Novel Multivalent, Single-Domain Antibody Targeting TcdA and TcdB Prevents Fulminant Clostridium difficile Infection in Mice

The Journal of Infectious Diseases ◽

10.1093/infdis/jiu196 ◽

2014 ◽

Vol 210 (6) ◽

pp. 964-972 ◽

Author(s):

Zhiyong Yang ◽

Diane Schmidt ◽

Weilong Liu ◽

Shan Li ◽

Lianfa Shi ◽

...

Keyword(s):

Clostridium Difficile ◽

Clostridium Difficile Infection ◽

Single Domain ◽

Single Domain Antibody ◽

Domain Antibody ◽

Antibody Targeting

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Abstract 2451: A novel single domain antibody targeting TIGIT for cancer use in combination therapies

10.1158/1538-7445.am2021-2451 ◽

2021 ◽

Author(s):

Botong Hua ◽

Ming Yang ◽

Jie Xue ◽

Chen Dong ◽

Yi-Ting Mao ◽

...

Keyword(s):

Single Domain ◽

Combination Therapies ◽

Single Domain Antibody ◽

Domain Antibody ◽

Antibody Targeting

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The Molecular Mechanism of Shiga Toxin Stx2e Neutralization by a Single-domain Antibody Targeting the Cell Receptor-binding Domain

Journal of Biological Chemistry ◽

10.1074/jbc.m114.566257 ◽

2014 ◽

Vol 289 (36) ◽

pp. 25374-25381 ◽

Author(s):

Alvin W. H. Lo ◽

Kristof Moonens ◽

Maia De Kerpel ◽

Lea Brys ◽

Els Pardon ◽

...

Keyword(s):

Molecular Mechanism ◽

Receptor Binding ◽

Shiga Toxin ◽

Cell Receptor ◽

Binding Domain ◽

Single Domain ◽

Receptor Binding Domain ◽

Single Domain Antibody ◽

Domain Antibody ◽

Antibody Targeting

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An Intrabody Based on a Llama Single-domain Antibody Targeting the N-terminal α-Helical Multimerization Domain of HIV-1 Rev Prevents Viral Production

Journal of Biological Chemistry ◽

10.1074/jbc.m110.112490 ◽

2010 ◽

Vol 285 (28) ◽

pp. 21768-21780 ◽

Author(s):

Thomas Vercruysse ◽

Els Pardon ◽

Els Vanstreels ◽

Jan Steyaert ◽

Dirk Daelemans

Keyword(s):

Single Domain ◽

Viral Production ◽

Single Domain Antibody ◽

Domain Antibody ◽

Antibody Targeting ◽

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An Intrabody based on a Llama Single-domain Antibody Targeting the N-terminal α-Helical Multimerization Domain of HIV-1 Rev Inhibits Viral Replication

Antiviral Research ◽

10.1016/j.antiviral.2010.02.340 ◽

2010 ◽

Vol 86 (1) ◽

pp. A22

Author(s):

Dirk Daelemans ◽

Thomas Vercruysse ◽

Els Pardon ◽

Els Vanstreels ◽

Jan Steyaert

Keyword(s):

Viral Replication ◽

Single Domain ◽

Single Domain Antibody ◽

Domain Antibody ◽

Antibody Targeting ◽

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Single domain antibody coated gold nanoparticles as enhancer for Clostridium difficile toxin detection by electrochemical impedance immunosensors

Bioelectrochemistry ◽

10.1016/j.bioelechem.2014.10.003 ◽

2015 ◽

Vol 101 ◽

pp. 153-158 ◽

Author(s):

Zanzan Zhu ◽

Lianfa Shi ◽

Hanping Feng ◽

H. Susan Zhou

Keyword(s):

Gold Nanoparticles ◽

Clostridium Difficile ◽

Electrochemical Impedance ◽

Single Domain ◽

Single Domain Antibody ◽

Toxin Detection ◽

Domain Antibody ◽

Clostridium Difficile Toxin

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A Novel Single Domain Antibody Targeting FliC Flagellin of Salmonella enterica for Effective Inhibition of Host Cell Invasion

Frontiers in Microbiology ◽

10.3389/fmicb.2019.02665 ◽

2019 ◽

Vol 10 ◽

Author(s):

Jennifer Huen ◽

Zhun Yan ◽

Jeremy Iwashkiw ◽

Shraddha Dubey ◽

Maria C. Gimenez ◽

...

Keyword(s):

Host Cell ◽

Cell Invasion ◽

Salmonella Enterica ◽

Single Domain ◽

Host Cell Invasion ◽

Single Domain Antibody ◽

Domain Antibody ◽

Effective Inhibition ◽

Antibody Targeting

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A Single-Domain Antibody Targeting Complement Component C5 Acts as a Selective Inhibitor of the Terminal Pathway of the Complement System and Thus Functionally Mimicks the C-Terminal Domain of the Staphylococcus aureus SSL7 Protein

Frontiers in Immunology ◽

10.3389/fimmu.2018.02822 ◽

2018 ◽

Vol 9 ◽

Author(s):

Laure Yatime ◽

Nicolas S. Merle ◽

Annette G. Hansen ◽

Niels Anton Friis ◽

Jakob A. Østergaard ◽

...

Keyword(s):

Staphylococcus Aureus ◽

Complement System ◽

Selective Inhibitor ◽

Complement Component ◽

Single Domain ◽

Single Domain Antibody ◽

Terminal Domain ◽

Domain Antibody ◽

Antibody Targeting ◽

The Complement System

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Application of Assisted Design of Antibody and Protein Therapeutics (ADAPT) improves efficacy of a Clostridium difficile toxin A single-domain antibody

Scientific Reports ◽

10.1038/s41598-018-20599-4 ◽

2018 ◽

Vol 8 (1) ◽

Author(s):

Traian Sulea ◽

Greg Hussack ◽

Shannon Ryan ◽

Jamshid Tanha ◽

Enrico O. Purisima

Keyword(s):

Clostridium Difficile ◽

Protein Therapeutics ◽

Single Domain ◽

Single Domain Antibody ◽

Toxin A ◽

Domain Antibody ◽

Clostridium Difficile Toxin ◽

Clostridium Difficile Toxin A

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Production and Characterization of Novel Camel Single Domain Antibody Targeting Mouse Vascular Endothelial Growth Factor

Monoclonal Antibodies in Immunodiagnosis and Immunotherapy ◽

10.1089/mab.2016.0001 ◽

2016 ◽

Vol 35 (3) ◽

pp. 167-171 ◽

Author(s):

Fatemeh Kazemi-Lomedasht ◽

Mahdi Behdani ◽

Mahdi Habibi-Anbouhi ◽

Delavar Shahbazzadeh

Keyword(s):

Vascular Endothelial Growth Factor ◽

Growth Factor ◽

Single Domain ◽

Vascular Endothelial ◽

Single Domain Antibody ◽

Domain Antibody ◽

Antibody Targeting ◽

Endothelial Growth Factor

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Faculty Opinions recommendation of Crystal structure of a shark single-domain antibody V region in complex with lysozyme.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1024018.285841 ◽

2005 ◽

Author(s):

Christopher Garcia

Keyword(s):

Crystal Structure ◽

Single Domain ◽

Single Domain Antibody ◽

Domain Antibody ◽

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