scholarly journals Neutralizing Antibody Correlates Analysis of Tetravalent Dengue Vaccine Efficacy Trials in Asia and Latin America

2017 ◽  
Vol 217 (5) ◽  
pp. 742-753 ◽  
Author(s):  
Zoe Moodie ◽  
Michal Juraska ◽  
Ying Huang ◽  
Yingying Zhuang ◽  
Youyi Fong ◽  
...  
Keyword(s):  
Latin America ◽  
Vaccine Efficacy ◽  
Neutralizing Antibody ◽  
Dengue Vaccine ◽  
Efficacy Trials

scholarly journals Four-year safety follow-up of the tetravalent dengue vaccine efficacy randomized controlled trials in Asia and Latin America

2018 ◽  
Vol 24 (7) ◽  
pp. 755-763 ◽  
Author(s):  
J.L. Arredondo-García ◽  
S.R. Hadinegoro ◽  
H. Reynales ◽  
M.N. Chua ◽  
D.M. Rivera Medina ◽  
...  
Keyword(s):  
Latin America ◽  
Randomized Controlled Trials ◽  
Vaccine Efficacy ◽  
Controlled Trials ◽  
Dengue Vaccine ◽  
Randomized Controlled

scholarly journals Impact of Dengue Vaccination on Serological Diagnosis: Insights From Phase III Dengue Vaccine Efficacy Trials

2017 ◽  
Vol 66 (8) ◽  
pp. 1164-1172 ◽  
Author(s):  
Eric Plennevaux ◽  
Annick Moureau ◽  
José L Arredondo-García ◽  
Luis Villar ◽  
Punnee Pitisuttithum ◽  
...  
Keyword(s):  
Vaccine Efficacy ◽  
Serological Diagnosis ◽  
Phase Iii ◽  
Dengue Vaccine ◽  
Efficacy Trials

scholarly journals Magnitude and Breadth of the Neutralizing Antibody Response in the RV144 and Vax003 HIV-1 Vaccine Efficacy Trials

2012 ◽  
Vol 206 (3) ◽  
pp. 431-441 ◽  
Author(s):  
D. C. Montefiori ◽  
C. Karnasuta ◽  
Y. Huang ◽  
H. Ahmed ◽  
P. Gilbert ◽  
...  
Keyword(s):  
Antibody Response ◽  
Vaccine Efficacy ◽  
Neutralizing Antibody ◽  
Efficacy Trials ◽  
Hiv 1

OR23 HLA class II genes correlate with protective neutralizing antibody titers in a dengue vaccine efficacy trial

2018 ◽  
Vol 79 ◽  
pp. 29
Author(s):  
Aviva Geretz ◽  
Shida Shangguan ◽  
Chris Bryant ◽  
Philip Ehrenberg ◽  
Merlin Robb ◽  
...  
Keyword(s):  
Vaccine Efficacy ◽  
Neutralizing Antibody ◽  
Class Ii ◽  
Hla Class Ii ◽  
Efficacy Trial ◽  
Dengue Vaccine ◽  
Antibody Titers

Twenty Years of Outpatient Respiratory Syncytial Virus Infection: A Framework for Vaccine Efficacy Trials

PEDIATRICS ◽  
1997 ◽  
Vol 99 (2) ◽  
pp. e7-e7 ◽  
Author(s):  
R. G. Fisher ◽  
W. C. Gruber ◽  
K. M. Edwards ◽  
G. W. Reed ◽  
S. J. Tollefson ◽  
...  
Keyword(s):  
Respiratory Syncytial Virus ◽  
Virus Infection ◽  
Respiratory Syncytial Virus Infection ◽  
Vaccine Efficacy ◽  
Efficacy Trials ◽  
Syncytial Virus

scholarly journals Contrasting Adult and Infant Immune Responses to HIV Infection and Vaccination

2015 ◽  
Vol 23 (2) ◽  
pp. 84-94 ◽  
Author(s):  
David R. Martinez ◽  
Sallie R. Permar ◽  
Genevieve G. Fouda
Keyword(s):  
Immune Responses ◽  
Hiv Infection ◽  
Vaccine Efficacy ◽  
Neutralizing Antibody ◽  
Hiv Vaccine ◽  
Antibody Responses ◽  
Hiv Vaccines ◽  
Vaccine Candidates ◽  
Protective Antibodies ◽  
Pediatric Populations

ABSTRACTExtensive studies have demonstrated that infant immune responses are distinct from those of adults. Despite these differences, infant immunization can elicit protective immune responses at levels comparable to or, in some cases, higher than adult immune responses to many vaccines. To date, only a few HIV vaccine candidates have been tested in infant populations, and none of them evaluated vaccine efficacy. Recent exciting studies showing that HIV-infected infants can develop broad neutralizing antibody responses and that some HIV vaccine regimens can elicit high levels of potentially protective antibodies in infants provide support for the development and testing of HIV vaccines in pediatric populations. In this review, we discuss the differences in adult and infant immune responses in the setting of HIV infection and vaccination.

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