scholarly journals In vitro activity of new quinolones against Clostridium difficile

2001 ◽  
Vol 47 (2) ◽  
pp. 195-197 ◽  
Author(s):  
R. Alonso
Drugs ◽  
1995 ◽  
Vol 49 (Supplement 2) ◽  
pp. 233-234
Author(s):  
Carl Erik Nord ◽  
Ann Lindmark ◽  
Ingela Persson

Anaerobe ◽  
2013 ◽  
Vol 20 ◽  
pp. 32-35 ◽  
Author(s):  
Mamun-Ur Rashid ◽  
Helena Martinez Lozano ◽  
Andrej Weintraub ◽  
Carl Erik Nord

2004 ◽  
Vol 48 (6) ◽  
pp. 2280-2282 ◽  
Author(s):  
Grit Ackermann ◽  
Birgit Löffler ◽  
Daniela Adler ◽  
Arne C. Rodloff

ABSTRACT Clostridium difficile remains the major cause of nosocomial diarrhea. Reports on impaired susceptibility of C. difficile to metronidazole and vancomycin and frequent relapses of patients after therapy necessitate the search for new substances. With this study, the activity of OPT-80, a new macrocycle, against 207 C. difficile strains and against other obligately anaerobic bacteria was tested. OPT-80 showed high in vitro activity against all C. difficile strains tested.


2002 ◽  
Vol 46 (4) ◽  
pp. 1136-1140 ◽  
Author(s):  
Ellie J. C. Goldstein ◽  
Diane M. Citron ◽  
C. Vreni Merriam ◽  
Yumi A. Warren ◽  
Kerin L. Tyrrell ◽  
...  

ABSTRACT We studied the in vitro activity of ertapenem against 469 less frequently identified anaerobes from 11 genera and 52 species isolated from human infections. Ertapenem was uniformly active against 460 of 469 (98%) strains at concentrations of ≤4 μg/ml. Only 4 of 14 Clostridium difficile, 1 of 11 Clostridium innocuum, and 4 of 6 Lactobacillus sp. strains required ertapenem concentrations of ≥8 μg/ml for inhibition.


1987 ◽  
Vol 31 (3) ◽  
pp. 461-462 ◽  
Author(s):  
H Faruki ◽  
A C Niles ◽  
R L Heeren ◽  
P R Murray

2000 ◽  
Vol 6 (3) ◽  
pp. 148-150 ◽  
Author(s):  
Hideaki Ikejima ◽  
Hiroyuki Yamamoto ◽  
Kazuo Ishida ◽  
Mitsuo Kaku ◽  
Jingoro Shimada

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