scholarly journals Comparison of serological responses to single-dose azithromycin (2 g) versus benzathine penicillin G in the treatment of early syphilis in HIV-infected patients in an area of low prevalence of macrolide-resistantTreponema palliduminfection

2015 ◽  
Vol 71 (3) ◽  
pp. 775-782 ◽  
Author(s):  
Chia-Jui Yang ◽  
Hung-Jen Tang ◽  
Sui-Yuan Chang ◽  
Szu-Min Hsieh ◽  
Kuan-Yeh Lee ◽  
...  
2014 ◽  
Vol 60 (4) ◽  
pp. 653-660 ◽  
Author(s):  
Anuradha Ganesan ◽  
Octavio Mesner ◽  
Jason F. Okulicz ◽  
Thomas O'Bryan ◽  
Robert G. Deiss ◽  
...  

We examined treatment responses in >400 cases of early syphilis in human immunodeficiency virus-infected individuals. Serologic outcomes did not vary as a function of the treatment regimen. These results support the use of a single dose of benzathine penicillin as treatment.


2014 ◽  
Vol 17 (1) ◽  
pp. 18993 ◽  
Author(s):  
Mao-Song Tsai ◽  
Chia-Jui Yang ◽  
Nan-Yao Lee ◽  
Szu-Min Hsieh ◽  
Yu-Hui Lin ◽  
...  

2006 ◽  
Vol 17 (5) ◽  
pp. 344-348 ◽  
Author(s):  
Hugo McClean ◽  
David Daniels ◽  
Chris Carne ◽  
Paul Bunting ◽  
Rob Miller ◽  
...  

Data were provided by 131 clinics, and 56% of cases were managed in clinics in the London regions in 2003. Three clinics (2%) do not routinely screen new patients for syphilis, and 28 clinics (21%) do not routinely screen 'rebook' patients who have had a new partner. More than 80% of clinics routinely conduct cardiovascular and neurological examinations, although chest radiography is only performed by 50% of clinics and lumbar puncture by 13%. Only 19 (14%) clinics indicated not routinely using the recommended procaine penicillin G (PPG) regimen or one- or two-dose benzathine penicillin G (BPG) regimens for early syphilis, with 57% providing two doses of BPG 2.4 g, 40% providing PPG 750 mg for 10 days, and 15% providing one dose of BPG 2.4 g. Only seven clinics (5%) indicated that they provided treatment for early syphilis with PPG that is inferior to that recommended in the national guidelines. Only 18 clinics specified using the recommended dose and duration (or in excess of this) of PPG for neurosyphilis for cases with HIV infection. Provision for management of severe penicillin reaction is good, although few patients are desensitized. All clinics report that contact tracing for early syphilis is provided, and is mainly the responsibility of health advisers. Compared with auditing outcomes, audit of management policies overestimated performance in contact tracing and provision of dark ground microscopy.


2017 ◽  
Vol 65 (10) ◽  
pp. 1683-1688 ◽  
Author(s):  
Yuping Cao ◽  
Xiaohong Su ◽  
Qianqiu Wang ◽  
Huazhong Xue ◽  
Xiaofeng Zhu ◽  
...  

2015 ◽  
Vol 91 (Suppl 1) ◽  
pp. A11.3-A12 ◽  
Author(s):  
Andrew Tomkins ◽  
Shazaad Ahmad ◽  
Darren E Cousins ◽  
Francisco Javier Vilar ◽  
Stephen P Higgins

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